Found 63 hits with Last Name = 'nagaoka' and Initial = 'y' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
M-phase inducer phosphatase 2
(Homo sapiens (Human)) | BDBM50571956
(CHEMBL4874608)Show SMILES OC(=O)C[C@H](Nc1nc(NCCCCCNC(=O)CCCNc2nc(N[C@@H](CC(O)=O)C(O)=O)nc(N[C@@H](Cc3ccc(O)cc3)C(O)=O)n2)nc(N[C@@H](Cc2c[nH]c3ccccc23)C(O)=O)n1)C(O)=O |r| | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
Competitive inhibition of recombinant human Cdc25B (351 to 380 residues) assessed as hydrolysis of substrate O-methylfluorescein phosphate by Linewea... |
Citation and Details
Article DOI: 10.1016/j.bmcl.2021.128265
BindingDB Entry DOI: 10.7270/Q26M3BNG |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 9.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19130
((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50229194
(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)Show SMILES CCC(=O)NCc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C21H21N3O2S/c1-2-20(25)23-13-14-5-7-15(8-6-14)21(26)24-18-12-16(9-10-17(18)22)19-4-3-11-27-19/h3-12H,2,13,22H2,1H3,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50365501
(CHEMBL1957458)Show SMILES CCN1CCN(C(=O)NCc2ccc(cc2)C(=O)Nc2cc(ccc2N)-c2cccs2)C(=O)C1=O Show InChI InChI=1S/C25H25N5O4S/c1-2-29-11-12-30(24(33)23(29)32)25(34)27-15-16-5-7-17(8-6-16)22(31)28-20-14-18(9-10-19(20)26)21-4-3-13-35-21/h3-10,13-14H,2,11-12,15,26H2,1H3,(H,27,34)(H,28,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50365503
(CHEMBL1957463)Show SMILES Nc1ccc(cc1NC(=O)c1ccc(CN(CCO)Cc2ccc3OCOc3c2)cc1)-c1cccs1 Show InChI InChI=1S/C28H27N3O4S/c29-23-9-8-22(27-2-1-13-36-27)15-24(23)30-28(33)21-6-3-19(4-7-21)16-31(11-12-32)17-20-5-10-25-26(14-20)35-18-34-25/h1-10,13-15,32H,11-12,16-18,29H2,(H,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50365502
(CHEMBL1957459)Show SMILES CN1CCN(CC1)C(=O)NCc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C24H27N5O2S/c1-28-10-12-29(13-11-28)24(31)26-16-17-4-6-18(7-5-17)23(30)27-21-15-19(8-9-20(21)25)22-3-2-14-32-22/h2-9,14-15H,10-13,16,25H2,1H3,(H,26,31)(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50365505
(CHEMBL1957464)Show SMILES Nc1ccc(cc1NC(=O)c1ccc(CNC(=O)N2CCOCC2)cc1)-c1cccs1 Show InChI InChI=1S/C23H24N4O3S/c24-19-8-7-18(21-2-1-13-31-21)14-20(19)26-22(28)17-5-3-16(4-6-17)15-25-23(29)27-9-11-30-12-10-27/h1-8,13-14H,9-12,15,24H2,(H,25,29)(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594395
(CHEMBL5189146)Show SMILES ONC(=O)c1ccc(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594394
(CHEMBL5195750) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594401
(CHEMBL5192796) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594396
(CHEMBL5172611)Show SMILES ONC(=O)c1ccc(CCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594398
(CHEMBL5175813)Show SMILES ONC(=O)c1ccc(CCCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50229194
(CHEMBL251819 | N-(2-amino-5-(thiophen-2-yl)phenyl)...)Show SMILES CCC(=O)NCc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C21H21N3O2S/c1-2-20(25)23-13-14-5-7-15(8-6-14)21(26)24-18-12-16(9-10-17(18)22)19-4-3-11-27-19/h3-12H,2,13,22H2,1H3,(H,23,25)(H,24,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19410
(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM19410
(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594397
(CHEMBL5193136)Show SMILES ONC(=O)c1ccc(CCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 580 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50594395
(CHEMBL5189146)Show SMILES ONC(=O)c1ccc(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 660 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50365501
(CHEMBL1957458)Show SMILES CCN1CCN(C(=O)NCc2ccc(cc2)C(=O)Nc2cc(ccc2N)-c2cccs2)C(=O)C1=O Show InChI InChI=1S/C25H25N5O4S/c1-2-29-11-12-30(24(33)23(29)32)25(34)27-15-16-5-7-17(8-6-16)22(31)28-20-14-18(9-10-19(20)26)21-4-3-13-35-21/h3-10,13-14H,2,11-12,15,26H2,1H3,(H,27,34)(H,28,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 670 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320762
(CHEMBL1164063 | N-(2-Aminophenyl)-4-(((biphenyl-4-...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C29H29N3O2/c30-27-8-4-5-9-28(27)31-29(34)26-16-12-23(13-17-26)21-32(18-19-33)20-22-10-14-25(15-11-22)24-6-2-1-3-7-24/h1-17,33H,18-21,30H2,(H,31,34) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50365503
(CHEMBL1957463)Show SMILES Nc1ccc(cc1NC(=O)c1ccc(CN(CCO)Cc2ccc3OCOc3c2)cc1)-c1cccs1 Show InChI InChI=1S/C28H27N3O4S/c29-23-9-8-22(27-2-1-13-36-27)15-24(23)30-28(33)21-6-3-19(4-7-21)16-31(11-12-32)17-20-5-10-25-26(14-20)35-18-34-25/h1-10,13-15,32H,11-12,16-18,29H2,(H,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 740 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320761
(CHEMBL1163973 | N-(2-Aminophenyl)-4-(((2-hydroxyet...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc(cc2)-c2cccs2)cc1 Show InChI InChI=1S/C27H27N3O2S/c28-24-4-1-2-5-25(24)29-27(32)23-13-9-21(10-14-23)19-30(15-16-31)18-20-7-11-22(12-8-20)26-6-3-17-33-26/h1-14,17,31H,15-16,18-19,28H2,(H,29,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320760
(CHEMBL1165774 | N-(2-Aminophenyl)-4-((3,3-dimethyl...)Show SMILES CN(C)C(=O)N(Cc1ccc(cc1)C(=O)Nc1ccccc1N)Cc1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C28H28N4O2S/c1-31(2)28(34)32(18-20-9-13-22(14-10-20)26-8-5-17-35-26)19-21-11-15-23(16-12-21)27(33)30-25-7-4-3-6-24(25)29/h3-17H,18-19,29H2,1-2H3,(H,30,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50365502
(CHEMBL1957459)Show SMILES CN1CCN(CC1)C(=O)NCc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C24H27N5O2S/c1-28-10-12-29(13-11-28)24(31)26-16-17-4-6-18(7-5-17)23(30)27-21-15-19(8-9-20(21)25)22-3-2-14-32-22/h2-9,14-15H,10-13,16,25H2,1H3,(H,26,31)(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50365505
(CHEMBL1957464)Show SMILES Nc1ccc(cc1NC(=O)c1ccc(CNC(=O)N2CCOCC2)cc1)-c1cccs1 Show InChI InChI=1S/C23H24N4O3S/c24-19-8-7-18(21-2-1-13-31-21)14-20(19)26-22(28)17-5-3-16(4-6-17)15-25-23(29)27-9-11-30-12-10-27/h1-8,13-14H,9-12,15,24H2,(H,25,29)(H,26,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 880 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320757
(CHEMBL1165443 | N-(2-aminophenyl)-4-((biphenyl-4-y...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2ccc(cc2)-c2ccccc2)cc1 Show InChI InChI=1S/C27H25N3O/c28-25-8-4-5-9-26(25)30-27(31)24-16-12-21(13-17-24)19-29-18-20-10-14-23(15-11-20)22-6-2-1-3-7-22/h1-17,29H,18-19,28H2,(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320754
(CHEMBL1163887 | N-(2-aminophenyl)-4-((4-(thiophen-...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2ccc(cc2)-c2cccs2)cc1 Show InChI InChI=1S/C25H23N3OS/c26-22-4-1-2-5-23(22)28-25(29)21-13-9-19(10-14-21)17-27-16-18-7-11-20(12-8-18)24-6-3-15-30-24/h1-15,27H,16-17,26H2,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320755
(CHEMBL1165102 | N-(2-aminophenyl)-4-((benzo[b]thio...)Show InChI InChI=1S/C23H21N3OS/c24-20-6-2-3-7-21(20)26-23(27)17-11-9-16(10-12-17)14-25-15-19-13-18-5-1-4-8-22(18)28-19/h1-13,25H,14-15,24H2,(H,26,27) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50365504
(CHEMBL407420)Show SMILES Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C24H25N3O4/c25-20-3-1-2-4-21(20)26-24(29)19-8-5-17(6-9-19)14-27(11-12-28)15-18-7-10-22-23(13-18)31-16-30-22/h1-10,13,28H,11-12,14-16,25H2,(H,26,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320759
(CHEMBL1164440 | N-(2-Aminophenyl)-4-((N-(4-(thioph...)Show SMILES CS(=O)(=O)N(Cc1ccc(cc1)C(=O)Nc1ccccc1N)Cc1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C26H25N3O3S2/c1-34(31,32)29(17-19-8-12-21(13-9-19)25-7-4-16-33-25)18-20-10-14-22(15-11-20)26(30)28-24-6-3-2-5-23(24)27/h2-16H,17-18,27H2,1H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50459720
(CHEMBL4210305)Show SMILES COc1ccc(CN(CCN(C)C)c2ccc(cn2)C(=O)Nc2ccccc2N)cc1 Show InChI InChI=1S/C24H29N5O2/c1-28(2)14-15-29(17-18-8-11-20(31-3)12-9-18)23-13-10-19(16-26-23)24(30)27-22-7-5-4-6-21(22)25/h4-13,16H,14-15,17,25H2,1-3H3,(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 measured a... |
ACS Med Chem Lett 9: 884-888 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00099
BindingDB Entry DOI: 10.7270/Q2JH3PTX |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM19410
(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 1.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50594397
(CHEMBL5193136)Show SMILES ONC(=O)c1ccc(CCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50594396
(CHEMBL5172611)Show SMILES ONC(=O)c1ccc(CCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320756
(CHEMBL1164335 | N-(2-aminophenyl)-4-((3-(thiophen-...)Show SMILES Nc1ccccc1NC(=O)c1ccc(CNCc2cccc(c2)-c2cccs2)cc1 Show InChI InChI=1S/C25H23N3OS/c26-22-7-1-2-8-23(22)28-25(29)20-12-10-18(11-13-20)16-27-17-19-5-3-6-21(15-19)24-9-4-14-30-24/h1-15,27H,16-17,26H2,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50365504
(CHEMBL407420)Show SMILES Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc3OCOc3c2)cc1 Show InChI InChI=1S/C24H25N3O4/c25-20-3-1-2-4-21(20)26-24(29)19-8-5-17(6-9-19)14-27(11-12-28)15-18-7-10-22-23(13-18)31-16-30-22/h1-10,13,28H,11-12,14-16,25H2,(H,26,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC2 |
Bioorg Med Chem Lett 22: 1926-30 (2012)
Article DOI: 10.1016/j.bmcl.2012.01.053
BindingDB Entry DOI: 10.7270/Q2FQ9X48 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50594397
(CHEMBL5193136)Show SMILES ONC(=O)c1ccc(CCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50594395
(CHEMBL5189146)Show SMILES ONC(=O)c1ccc(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50594395
(CHEMBL5189146)Show SMILES ONC(=O)c1ccc(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50594396
(CHEMBL5172611)Show SMILES ONC(=O)c1ccc(CCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50594398
(CHEMBL5175813)Show SMILES ONC(=O)c1ccc(CCCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50459720
(CHEMBL4210305)Show SMILES COc1ccc(CN(CCN(C)C)c2ccc(cn2)C(=O)Nc2ccccc2N)cc1 Show InChI InChI=1S/C24H29N5O2/c1-28(2)14-15-29(17-18-8-11-20(31-3)12-9-18)23-13-10-19(16-26-23)24(30)27-22-7-5-4-6-21(22)25/h4-13,16H,14-15,17,25H2,1-3H3,(H,27,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of recombinant human C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using HDAC substrate 3 measured after... |
ACS Med Chem Lett 9: 884-888 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00099
BindingDB Entry DOI: 10.7270/Q2JH3PTX |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50594398
(CHEMBL5175813)Show SMILES ONC(=O)c1ccc(CCCCN2CCN(CC2)C(c2ccccc2)c2ccccc2)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 6
(Mus musculus) | BDBM50594400
(CHEMBL5205202)Show SMILES ONC(=O)c1cccc(CN2CCN(CC2)C(c2ccccc2)c2ccccc2)c1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50594394
(CHEMBL5195750) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
MCE
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50594401
(CHEMBL5192796) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50320758
(CHEMBL1165580 | N-(2-Aminophenyl)-4-((methyl(4-(th...)Show SMILES CN(Cc1ccc(cc1)C(=O)Nc1ccccc1N)Cc1ccc(cc1)-c1cccs1 Show InChI InChI=1S/C26H25N3OS/c1-29(17-19-8-12-21(13-9-19)25-7-4-16-31-25)18-20-10-14-22(15-11-20)26(30)28-24-6-3-2-5-23(24)27/h2-16H,17-18,27H2,1H3,(H,28,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of HDAC1 |
Bioorg Med Chem 18: 3925-33 (2010)
Article DOI: 10.1016/j.bmc.2010.04.033
BindingDB Entry DOI: 10.7270/Q29S1R6H |
More data for this
Ligand-Target Pair | |
Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50594401
(CHEMBL5192796) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1021/acsmedchemlett.2c00081
BindingDB Entry DOI: 10.7270/Q2NG4VP5 |
More data for this
Ligand-Target Pair | |
Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
(Homo sapiens (Human)) | BDBM50459720
(CHEMBL4210305)Show SMILES COc1ccc(CN(CCN(C)C)c2ccc(cn2)C(=O)Nc2ccccc2N)cc1 Show InChI InChI=1S/C24H29N5O2/c1-28(2)14-15-29(17-18-8-11-20(31-3)12-9-18)23-13-10-19(16-26-23)24(30)27-22-7-5-4-6-21(22)25/h4-13,16H,14-15,17,25H2,1-3H3,(H,27,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Kansai University
Curated by ChEMBL
| Assay Description
Inhibition of human full length C-terminal His-tagged HDAC3/N-terminal GST-tagged human NCOR2 (395 to 489 residues) co-expressed in baculovirus infec... |
ACS Med Chem Lett 9: 884-888 (2018)
Article DOI: 10.1021/acsmedchemlett.8b00099
BindingDB Entry DOI: 10.7270/Q2JH3PTX |
More data for this
Ligand-Target Pair | |
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