Found 44 hits with Last Name = 'ong' and Initial = 'hw' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50589997
(CHEMBL5208060) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50589997
(CHEMBL5208060) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Calcium-dependent protein kinase 1
(Plasmodium Falciparum) | BDBM36336
(CID24762166 | Purfalcamine, 1)Show SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(Nc2ccc(cc2)C(=O)N2CCCCC2)c2ncn(-c3cccc(F)c3)c2n1 |r,wU:4.7,wD:1.0,(-8.67,.31,;-7.34,-.46,;-7.34,-2,;-6,-2.77,;-4.67,-2,;-4.67,-.46,;-6,.31,;-3.33,-2.77,;-2,-2,;-2,-.46,;-.67,.31,;-.67,1.85,;.67,2.62,;2,1.85,;3.33,2.62,;3.33,4.16,;2,4.93,;.67,4.16,;4.67,4.93,;4.67,6.47,;6,4.16,;6,2.62,;7.34,1.85,;8.67,2.62,;8.67,4.16,;7.34,4.93,;.67,-.46,;2.13,.02,;3.04,-1.23,;2.13,-2.47,;2.9,-3.81,;2.13,-5.14,;2.9,-6.47,;4.44,-6.47,;5.21,-5.14,;6.75,-5.14,;4.44,-3.81,;.67,-2,;-.67,-2.77,)| Show InChI InChI=1S/C29H33FN8O/c30-20-5-4-6-24(17-20)38-18-32-25-26(35-29(36-27(25)38)34-23-13-9-21(31)10-14-23)33-22-11-7-19(8-12-22)28(39)37-15-2-1-3-16-37/h4-8,11-12,17-18,21,23H,1-3,9-10,13-16,31H2,(H2,33,34,35,36)/t21-,23- | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50259155
((Z)-Hymenialdisine | Hymenialdisine)Show SMILES NC1=NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]c(Br)cc12 |t:1| Show InChI InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4- | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50259155
((Z)-Hymenialdisine | Hymenialdisine)Show SMILES NC1=NC(=O)\C(N1)=C1/CCNC(=O)c2[nH]c(Br)cc12 |t:1| Show InChI InChI=1S/C11H10BrN5O2/c12-6-3-5-4(7-10(19)17-11(13)16-7)1-2-14-9(18)8(5)15-6/h3,15H,1-2H2,(H,14,18)(H3,13,16,17,19)/b7-4- | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590019
(CHEMBL5176863)Show SMILES Cc1ccc(s1)-c1nc(Nc2ccc(cc2)C(=O)NCCCN2CCOCC2)ncc1Cl | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590018
(CHEMBL5186081)Show SMILES Clc1ccc(s1)-c1nc(Nc2ccc(cc2)C(=O)NCCCN2CCOCC2)ncc1Cl | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM5655
(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)Show SMILES CN1CC[C@@H]([C@H](O)C1)c1c(O)cc(O)c2c1oc(cc2=O)-c1ccccc1Cl |r| Show InChI InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1 | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590015
(CHEMBL5207951)Show SMILES Cc1ccc(s1)-c1nc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)ncc1Cl | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590014
(CHEMBL5180806)Show SMILES Brc1cnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)nc1-c1cc2ccccc2s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 165 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590017
(CHEMBL5173813)Show SMILES Clc1ccc(s1)-c1nc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)ncc1Cl | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590013
(CHEMBL5197512)Show SMILES Clc1cnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)nc1-c1cc2ccccc2s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590004
(CHEMBL5198648)Show SMILES CS(=O)(=O)CCCNC(=O)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 223 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590001
(CHEMBL5202515)Show SMILES CN1CCN(CCCNC(=O)c2ccc(Nc3nccc(n3)-c3cc4ccccc4s3)cc2)CC1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 226 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590002
(CHEMBL5179526)Show SMILES O=C(NCCCN1CCOCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 243 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590005
(CHEMBL5203707)Show SMILES O=C(NC1CC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 272 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590000
(CHEMBL5208765)Show SMILES CN1CCC(CC1)NC(=O)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 308 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590003
(CHEMBL5178028)Show SMILES CN(C)CCCNC(=O)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 328 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590012
(CHEMBL5191618)Show SMILES Fc1cnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)nc1-c1cc2ccccc2s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 456 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50424223
(CHEMBL2313853)Show SMILES Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3Cl)c12)C(=O)c1cccc(Cl)c1 |(27.03,-4.45,;26.56,-5.91,;27.47,-7.17,;26.56,-8.42,;25.08,-7.94,;23.75,-8.72,;22.42,-7.94,;21.08,-8.71,;22.42,-6.4,;21.08,-5.62,;19.75,-4.85,;23.75,-5.63,;23.74,-4.1,;25.07,-3.32,;25.07,-1.78,;23.73,-1.02,;22.4,-1.8,;22.41,-3.33,;21.08,-4.11,;25.08,-6.39,;29.01,-7.17,;29.78,-5.83,;29.78,-8.5,;29,-9.83,;29.77,-11.17,;31.32,-11.17,;32.08,-9.82,;33.62,-9.82,;31.31,-8.5,)| Show InChI InChI=1S/C21H12Cl2N4OS/c22-11-5-3-4-10(8-11)18(28)19-17(25)16-15(12-6-1-2-7-14(12)23)13(9-24)20(26)27-21(16)29-19/h1-8H,25H2,(H2,26,27) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50424223
(CHEMBL2313853)Show SMILES Nc1c(sc2nc(N)c(C#N)c(-c3ccccc3Cl)c12)C(=O)c1cccc(Cl)c1 |(27.03,-4.45,;26.56,-5.91,;27.47,-7.17,;26.56,-8.42,;25.08,-7.94,;23.75,-8.72,;22.42,-7.94,;21.08,-8.71,;22.42,-6.4,;21.08,-5.62,;19.75,-4.85,;23.75,-5.63,;23.74,-4.1,;25.07,-3.32,;25.07,-1.78,;23.73,-1.02,;22.4,-1.8,;22.41,-3.33,;21.08,-4.11,;25.08,-6.39,;29.01,-7.17,;29.78,-5.83,;29.78,-8.5,;29,-9.83,;29.77,-11.17,;31.32,-11.17,;32.08,-9.82,;33.62,-9.82,;31.31,-8.5,)| Show InChI InChI=1S/C21H12Cl2N4OS/c22-11-5-3-4-10(8-11)18(28)19-17(25)16-15(12-6-1-2-7-14(12)23)13(9-24)20(26)27-21(16)29-19/h1-8H,25H2,(H2,26,27) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 480 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590010
(CHEMBL5177833)Show SMILES FC(F)(F)COCc1ccc(s1)-c1ccnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)n1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 490 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590009
(CHEMBL5172803)Show SMILES Clc1ccc(s1)-c1ccnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)n1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 550 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50175688
((4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)p...)Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 Show InChI InChI=1S/C28H29N5OS/c34-27(33-17-12-23(13-18-33)32-15-3-4-16-32)20-7-9-22(10-8-20)30-28-29-14-11-24(31-28)26-19-21-5-1-2-6-25(21)35-26/h1-2,5-11,14,19,23H,3-4,12-13,15-18H2,(H,29,30,31) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 570 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50589998
(CHEMBL5185763)Show SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 695 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590007
(CHEMBL5203977)Show SMILES Clc1ccc(cc1Cl)-c1ccnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)n1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 698 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590011
(CHEMBL5201703)Show SMILES Cc1cnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)nc1-c1cc2ccccc2s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50175689
((4-(4-(benzo[b]thiophen-2-yl)pyrimidin-2-ylamino)p...)Show SMILES CN(C)C1CCN(CC1)C(=O)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 Show InChI InChI=1S/C26H27N5OS/c1-30(2)21-12-15-31(16-13-21)25(32)18-7-9-20(10-8-18)28-26-27-14-11-22(29-26)24-17-19-5-3-4-6-23(19)33-24/h3-11,14,17,21H,12-13,15-16H2,1-2H3,(H,27,28,29) | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 752 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50589999
(CHEMBL5195159)Show SMILES CN1CCN(CC1)C(=O)c1ccc(Nc2nccc(n2)-c2cc3ccccc3s2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 810 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590006
(CHEMBL5206250)Show SMILES O=C(N1CCC(CC1)N1CCCC1)c1ccc(Nc2nccc(n2)-c2cc3ccccc3o2)cc1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590008
(CHEMBL5194800)Show SMILES Cc1ccc(s1)-c1ccnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)n1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase 3
(Plasmodium falciparum (isolate 3D7)) | BDBM50590016
(CHEMBL5194982)Show SMILES Cc1cnc(Nc2ccc(cc2)C(=O)N2CCC(CC2)N2CCCC2)nc1-c1ccc(Cl)s1 | KEGG
UniProtKB/TrEMBL
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Schering-Plough Research Institute
Curated by ChEMBL
| |
Bioorg Med Chem Lett 15: 1333-6 (2005)
Article DOI: 10.1021/acs.jmedchem.2c00996 BindingDB Entry DOI: 10.7270/Q2445RF2 |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM7586
((2E)-3-[3-(benzyloxy)phenyl]prop-2-enal | Cinnamal...)Show InChI InChI=1S/C16H14O2/c17-11-5-9-14-8-4-10-16(12-14)18-13-15-6-2-1-3-7-15/h1-12H,13H2/b9-5+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM7570
((2E)-3-[2-(benzyloxy)phenyl]prop-2-enal | Cinnamal...)Show InChI InChI=1S/C16H14O2/c17-12-6-10-15-9-4-5-11-16(15)18-13-14-7-2-1-3-8-14/h1-12H,13H2/b10-6+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM7587
((2E)-3-{3-[(2-methylphenyl)methoxy]phenyl}prop-2-e...)Show InChI InChI=1S/C17H16O2/c1-14-6-2-3-9-16(14)13-19-17-10-4-7-15(12-17)8-5-11-18/h2-12H,13H2,1H3/b8-5+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM7571
((2E)-3-{2-[(2-methylphenyl)methoxy]phenyl}prop-2-e...)Show InChI InChI=1S/C17H16O2/c1-14-7-2-3-9-16(14)13-19-17-11-5-4-8-15(17)10-6-12-18/h2-12H,13H2,1H3/b10-6+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish)) | BDBM7569
((2E)-3-(3-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)Show InChI InChI=1S/C9H8O2/c10-6-2-4-8-3-1-5-9(11)7-8/h1-7,11H/b4-2+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 3.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM7568
((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)Show InChI InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 3.50E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D1
(Homo sapiens (Human)) | BDBM7569
((2E)-3-(3-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)Show InChI InChI=1S/C9H8O2/c10-6-2-4-8-3-1-5-9(11)7-8/h1-7,11H/b4-2+ | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 4.50E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 100 uM ATP/ [gamma-33P] ATP. 3... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish)) | BDBM7586
((2E)-3-[3-(benzyloxy)phenyl]prop-2-enal | Cinnamal...)Show InChI InChI=1S/C16H14O2/c17-11-5-9-14-8-4-10-16(12-14)18-13-15-6-2-1-3-7-15/h1-12H,13H2/b9-5+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish)) | BDBM7570
((2E)-3-[2-(benzyloxy)phenyl]prop-2-enal | Cinnamal...)Show InChI InChI=1S/C16H14O2/c17-12-6-10-15-9-4-5-11-16(15)18-13-14-7-2-1-3-8-14/h1-12H,13H2/b10-6+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish)) | BDBM7587
((2E)-3-{3-[(2-methylphenyl)methoxy]phenyl}prop-2-e...)Show InChI InChI=1S/C17H16O2/c1-14-6-2-3-9-16(14)13-19-17-10-4-7-15(12-17)8-5-11-18/h2-12H,13H2,1H3/b8-5+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish)) | BDBM7568
((2E)-3-(2-hydroxyphenyl)prop-2-enal | Cinnamaldehy...)Show InChI InChI=1S/C9H8O2/c10-7-3-5-8-4-1-2-6-9(8)11/h1-7,11H/b5-3+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 1.30E+5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 1/G2/mitotic-specific cyclin-B
(Marthasterias glacialis (starfish)) | BDBM7571
((2E)-3-{2-[(2-methylphenyl)methoxy]phenyl}prop-2-e...)Show InChI InChI=1S/C17H16O2/c1-14-7-2-3-9-16(14)13-19-17-11-5-4-8-15(17)10-6-12-18/h2-12H,13H2,1H3/b10-6+ | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 2.00E+5 | n/a | n/a | n/a | n/a | 7.2 | 30 |
Korea Research Institute of Bioscience and Biotechnology
| Assay Description Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32... |
Bioorg Med Chem Lett 10: 1819-22 (2000)
Article DOI: 10.1016/s0960-894x(00)00357-7 BindingDB Entry DOI: 10.7270/Q2Q23XFZ |
More data for this Ligand-Target Pair | |