Compile Data Set for Download or QSAR

Found 33 hits with Last Name = 'pacheco' and Initial = 'la'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysis				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysis				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Non-competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysis				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Competitive inhibition of Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate by Michaelis-Menten plot analysis				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase YopH (Yersinia enterocolitica)	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Yersinia enterocolitica YopH using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addi...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase YopH (Yersinia enterocolitica)	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Yersinia enterocolitica YopH using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addi...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase YopH (Yersinia enterocolitica)	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Yersinia enterocolitica YopH using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addi...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase YopH (Yersinia enterocolitica)	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Yersinia enterocolitica YopH using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addi...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human Ptp1B using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466476 (CHEMBL4279400) Show SMILES Clc1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1Cl Show InChI InChI=1S/C18H13Cl2N3S/c19-15-9-8-12(10-16(15)20)11-21-23-18(24)22-17-7-3-5-13-4-1-2-6-14(13)17/h1-11H,(H2,22,23,24)/b21-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.34E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466477 (CHEMBL4294511) Show SMILES COc1ccc(NC(=S)N\N=C\c2ccc(cc2)[N+]([O-])=O)cc1 Show InChI InChI=1S/C15H14N4O3S/c1-22-14-8-4-12(5-9-14)17-15(23)18-16-10-11-2-6-13(7-3-11)19(20)21/h2-10H,1H3,(H2,17,18,23)/b16-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.51E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 12 (Homo sapiens (Human))	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.57E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP-PEST using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measu...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human Ptp1B using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466480 (CHEMBL4280931) Show SMILES S=C(N\N=C\c1ccc2OCOc2c1)Nc1cccc2ccccc12 Show InChI InChI=1S/C19H15N3O2S/c25-19(21-16-7-3-5-14-4-1-2-6-15(14)16)22-20-11-13-8-9-17-18(10-13)24-12-23-17/h1-11H,12H2,(H2,21,22,25)/b20-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466481 (CHEMBL4285399) Show SMILES COc1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1OC Show InChI InChI=1S/C20H19N3O2S/c1-24-18-11-10-14(12-19(18)25-2)13-21-23-20(26)22-17-9-5-7-15-6-3-4-8-16(15)17/h3-13H,1-2H3,(H2,22,23,26)/b21-13+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Low molecular weight protein-tyrosine phosphatase A (Mycobacterium tuberculosis)	BDBM50466483 (CHEMBL4287324) Show SMILES S=C(N\N=C\c1ccc2ccccc2c1)Nc1cccc2ccccc12 Show InChI InChI=1S/C22H17N3S/c26-22(24-21-11-5-9-18-7-3-4-10-20(18)21)25-23-15-16-12-13-17-6-1-2-8-19(17)14-16/h1-15H,(H2,24,25,26)/b23-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpA using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
TYR_PHOSPHATASE_2 domain-containing protein (Mycobacterium tuberculosis)	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant Mycobacterium tuberculosis PtpB using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate a...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human Ptp1B using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 12 (Homo sapiens (Human))	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP-PEST using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measu...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 1 (Homo sapiens (Human))	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human Ptp1B using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human LYP using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured e...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human LYP using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured e...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM50466482 (CHEMBL4282817) Show SMILES Cc1ccc(NC(=S)N\N=C\c2ccc(o2)-c2cc(ccc2Cl)C(F)(F)F)cc1 Show InChI InChI=1S/C20H15ClF3N3OS/c1-12-2-5-14(6-3-12)26-19(29)27-25-11-15-7-9-18(28-15)16-10-13(20(22,23)24)4-8-17(16)21/h2-11H,1H3,(H2,26,27,29)/b25-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human LYP using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured e...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Homo sapiens (Human))	BDBM50466478 (CHEMBL4288744) Show SMILES FC(F)(F)c1ccc(Cl)c(c1)-c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)o1 Show InChI InChI=1S/C23H15ClF3N3OS/c24-19-10-8-15(23(25,26)27)12-18(19)21-11-9-16(31-21)13-28-30-22(32)29-20-7-3-5-14-4-1-2-6-17(14)20/h1-13H,(H2,29,30,32)/b28-13+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human LYP using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measured e...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 12 (Homo sapiens (Human))	BDBM50466479 (CHEMBL4280516) Show SMILES S=C(N\N=C\c1ccc(cc1)-c1ccccc1)Nc1cccc2ccccc12 Show InChI InChI=1S/C24H19N3S/c28-24(26-23-12-6-10-21-9-4-5-11-22(21)23)27-25-17-18-13-15-20(16-14-18)19-7-2-1-3-8-19/h1-17H,(H2,26,27,28)/b25-17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP-PEST using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measu...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 12 (Homo sapiens (Human))	BDBM50466475 (CHEMBL4292242) Show SMILES [O-][N+](=O)c1ccc(\C=N\NC(=S)Nc2cccc3ccccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-22(24)15-10-8-13(9-11-15)12-19-21-18(25)20-17-7-3-5-14-4-1-2-6-16(14)17/h1-12H,(H2,20,21,25)/b19-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidade Federal de Santa Catarina Curated by ChEMBL					Assay Description Inhibition of recombinant human PTP-PEST using p-nitrophenyl phosphate as substrate preincubated for 10 mins followed by substrate addition and measu...				Bioorg Med Chem 26: 5742-5750 (2018) Article DOI: 10.1016/j.bmc.2018.10.030 BindingDB Entry DOI: 10.7270/Q26T0QBX
					More data for this Ligand-Target Pair