Compile Data Set for Download or QSAR

Found 73 hits with Last Name = 'peet' and Initial = 'c'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	7.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Thromboxane A2 receptor (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of TP receptor				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259613 (CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl3NO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259612 (CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-5-7-19(27-11-12-4-6-15(23)10-17(12)22)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Antagonist activity at human recombinant EP1 receptor expressed in CHO cells assessed as inhibition of PGE2-mediated intracellular calcium mobilizati...				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414022 (CHEMBL2110364 | GSK-180100B) Show SMILES Cc1cc(nn1Cc1cc(Br)ccc1OCc1ccc(Cl)cc1Cl)C([O-])=O Show InChI InChI=1S/C19H15BrCl2N2O3/c1-11-6-17(19(25)26)23-24(11)9-13-7-14(20)3-5-18(13)27-10-12-2-4-15(21)8-16(12)22/h2-8H,9-10H2,1H3,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.129	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50197898 (6-(2-(2-(2,4-difluorobenzyloxy)-5-chlorophenyl)cyc...) Show SMILES OC(=O)c1cccc(n1)C1=C(CCC1)c1cc(Cl)ccc1OCc1ccc(F)cc1F |t:10| Show InChI InChI=1S/C24H18ClF2NO3/c25-15-8-10-23(31-13-14-7-9-16(26)12-20(14)27)19(11-15)17-3-1-4-18(17)21-5-2-6-22(28-21)24(29)30/h2,5-12H,1,3-4,13H2,(H,29,30)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.51	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121279 (2-Amino-1-[2-(5-ethyl-1H-imidazol-2-yl)-2,3-dihydr...) Show SMILES CCC[C@H](N)C(=O)N1[C@@H](Cc2ccccc12)c1ncc(CC)[nH]1 Show InChI InChI=1S/C18H24N4O/c1-3-7-14(19)18(23)22-15-9-6-5-8-12(15)10-16(22)17-20-11-13(4-2)21-17/h5-6,8-9,11,14,16H,3-4,7,10,19H2,1-2H3,(H,20,21)/t14-,16-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liver				J Med Chem 45: 5303-10 (2002) BindingDB Entry DOI: 10.7270/Q2736Q7X
					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121284 (2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...) Show SMILES CCC[C@H](N)C(=O)N1[C@@H](Cc2ccccc12)c1ncc(C)[nH]1 Show InChI InChI=1S/C17H22N4O/c1-3-6-13(18)17(22)21-14-8-5-4-7-12(14)9-15(21)16-19-10-11(2)20-16/h4-5,7-8,10,13,15H,3,6,9,18H2,1-2H3,(H,19,20)/t13-,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liver				J Med Chem 45: 5303-10 (2002) BindingDB Entry DOI: 10.7270/Q2736Q7X
					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121282 ((S)-1-((S)-2-aminobutanoyl)-N-butylindoline-2-carb...) Show SMILES CCCCNC(=O)[C@@H]1Cc2ccccc2N1C(=O)[C@@H](N)CC Show InChI InChI=1S/C17H25N3O2/c1-3-5-10-19-16(21)15-11-12-8-6-7-9-14(12)20(15)17(22)13(18)4-2/h6-9,13,15H,3-5,10-11,18H2,1-2H3,(H,19,21)/t13-,15-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liver				J Med Chem 45: 5303-10 (2002) BindingDB Entry DOI: 10.7270/Q2736Q7X
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50197899 (5-(2-(2-(benzyloxy)-5-(trifluoromethyl)phenyl)cycl...) Show SMILES OC(=O)c1cncc(c1)C1=C(CCC1)c1cc(ccc1OCc1ccccc1)C(F)(F)F |t:10| Show InChI InChI=1S/C25H20F3NO3/c26-25(27,28)19-9-10-23(32-15-16-5-2-1-3-6-16)22(12-19)21-8-4-7-20(21)17-11-18(24(30)31)14-29-13-17/h1-3,5-6,9-14H,4,7-8,15H2,(H,30,31)	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259613 (CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl3NO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259612 (CHEMBL513491 | sodium 6-(5-chloro-2-(2-chloro-4-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-5-7-19(27-11-12-4-6-15(23)10-17(12)22)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50259548 (6-(5'-chloro-2'-isobutoxy-biphenyl-2-yl)-pyridine-...) Show SMILES CC(C)COc1ccc(Cl)cc1-c1ccccc1-c1cccc(n1)C([O-])=O Show InChI InChI=1S/C22H20ClNO3/c1-14(2)13-27-21-11-10-15(23)12-18(21)16-6-3-4-7-17(16)19-8-5-9-20(24-19)22(25)26/h3-12,14H,13H2,1-2H3,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121280 (2-Amino-1-[2-(5-methyl-1H-imidazol-2-yl)-2,3-dihyd...) Show SMILES CC[C@H](N)C(=O)N1[C@@H](Cc2ccccc12)c1ncc(C)[nH]1 Show InChI InChI=1S/C16H20N4O/c1-3-12(17)16(21)20-13-7-5-4-6-11(13)8-14(20)15-18-9-10(2)19-15/h4-7,9,12,14H,3,8,17H2,1-2H3,(H,18,19)/t12-,14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liver				J Med Chem 45: 5303-10 (2002) BindingDB Entry DOI: 10.7270/Q2736Q7X
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414026 (CHEMBL466101) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2F)n1 Show InChI InChI=1S/C20H14ClF2NO3/c21-14-5-7-19(27-11-12-4-6-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.1	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414032 (CHEMBL511252) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCC2CCCC2)n1 Show InChI InChI=1S/C19H20ClNO3/c20-15-8-9-18(24-12-13-4-1-2-5-13)14(10-15)11-16-6-3-7-17(21-16)19(22)23/h3,6-10,13H,1-2,4-5,11-12H2,(H,22,23)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121283 (2-Amino-1-[2-(1H-imidazol-2-yl)-2,3-dihydro-indol-...) Show SMILES CCC[C@H](N)C(=O)N1[C@@H](Cc2ccccc12)c1ncc[nH]1 Show InChI InChI=1S/C16H20N4O/c1-2-5-12(17)16(21)20-13-7-4-3-6-11(13)10-14(20)15-18-8-9-19-15/h3-4,6-9,12,14H,2,5,10,17H2,1H3,(H,18,19)/t12-,14-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liver				J Med Chem 45: 5303-10 (2002) BindingDB Entry DOI: 10.7270/Q2736Q7X
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414028 (CHEMBL466103) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2Cl)n1 Show InChI InChI=1S/C20H15Cl2NO3/c21-15-8-9-19(26-12-13-4-1-2-6-17(13)22)14(10-15)11-16-5-3-7-18(23-16)20(24)25/h1-10H,11-12H2,(H,24,25)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414030 (CHEMBL257998) Show SMILES CC(C)COc1ccc(Cl)cc1Cc1cccc(n1)C([O-])=O Show InChI InChI=1S/C17H18ClNO3/c1-11(2)10-22-16-7-6-13(18)8-12(16)9-14-4-3-5-15(19-14)17(20)21/h3-8,11H,9-10H2,1-2H3,(H,20,21)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414029 (CHEMBL467113) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2)n1 Show InChI InChI=1S/C20H15Cl2NO3/c21-15-6-4-13(5-7-15)12-26-19-9-8-16(22)10-14(19)11-17-2-1-3-18(23-17)20(24)25/h1-10H,11-12H2,(H,24,25)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	39.8	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414027 (CHEMBL466102) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2c(F)cc(F)cc2F)n1 Show InChI InChI=1S/C20H13ClF3NO3/c21-12-4-5-19(28-10-15-16(23)8-13(22)9-17(15)24)11(6-12)7-14-2-1-3-18(25-14)20(26)27/h1-6,8-9H,7,10H2,(H,26,27)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414024 (CHEMBL508276) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2F)n1 Show InChI InChI=1S/C20H15ClFNO3/c21-15-8-9-19(26-12-13-4-1-2-6-17(13)22)14(10-15)11-16-5-3-7-18(23-16)20(24)25/h1-10H,11-12H2,(H,24,25)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79.4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414025 (CHEMBL511733) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2)n1 Show InChI InChI=1S/C20H15ClFNO3/c21-15-6-9-19(26-12-13-4-7-16(22)8-5-13)14(10-15)11-17-2-1-3-18(23-17)20(24)25/h1-10H,11-12H2,(H,24,25)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414031 (CHEMBL468723) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCC2CCCCC2)n1 Show InChI InChI=1S/C20H22ClNO3/c21-16-9-10-19(25-13-14-5-2-1-3-6-14)15(11-16)12-17-7-4-8-18(22-17)20(23)24/h4,7-11,14H,1-3,5-6,12-13H2,(H,23,24)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414023 (CHEMBL258041) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccccc2)n1 Show InChI InChI=1S/C20H16ClNO3/c21-16-9-10-19(25-13-14-5-2-1-3-6-14)15(11-16)12-17-7-4-8-18(22-17)20(23)24/h1-11H,12-13H2,(H,23,24)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP1 subtype (Homo sapiens (Human))	BDBM50414033 (CHEMBL511919) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCC2CC2)n1 Show InChI InChI=1S/C17H16ClNO3/c18-13-6-7-16(22-10-11-4-5-11)12(8-13)9-14-2-1-3-15(19-14)17(20)21/h1-3,6-8,11H,4-5,9-10H2,(H,20,21)/p-1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP1 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177043 (CHEMBL3814671) Show SMILES [H][C@@]12CC[C@@]([H])(C1)[C@H](C2)n1ncc2cnc(Nc3ccc(CNC4CCN(C)CC4)cc3)nc12 |r| Show InChI InChI=1S/C25H33N7/c1-31-10-8-21(9-11-31)26-14-17-3-6-22(7-4-17)29-25-27-15-20-16-28-32(24(20)30-25)23-13-18-2-5-19(23)12-18/h3-4,6-7,15-16,18-19,21,23,26H,2,5,8-14H2,1H3,(H,27,29,30)/t18-,19+,23+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177042 (CHEMBL3730906) Show SMILES Cn1ccc2cc(ccc12)-c1cnc2cnc(cn12)-c1cccc(c1)C(N)=O Show InChI InChI=1S/C22H17N5O/c1-26-8-7-16-10-15(5-6-19(16)26)20-11-25-21-12-24-18(13-27(20)21)14-3-2-4-17(9-14)22(23)28/h2-13H,1H3,(H2,23,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	427	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Prostacyclin receptor (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of IP receptor				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of EP3 receptor by FLIPR assay				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP2 subtype (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.58E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of EP2 receptor				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50177033 (CHEMBL3813839) Show SMILES COc1cc(ccc1O)-c1cnn2ccc(Nc3ccc(cc3)C(C)C)nc12 Show InChI InChI=1S/C22H22N4O2/c1-14(2)15-4-7-17(8-5-15)24-21-10-11-26-22(25-21)18(13-23-26)16-6-9-19(27)20(12-16)28-3/h4-14,27H,1-3H3,(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177041 (CHEMBL3814491) Show SMILES NC(=O)c1nc(nc2n(CCc3ccccc3)c(=O)[nH]c12)-c1ccc2ncccc2c1 Show InChI InChI=1S/C23H18N6O2/c24-20(30)18-19-22(29(23(31)27-19)12-10-14-5-2-1-3-6-14)28-21(26-18)16-8-9-17-15(13-16)7-4-11-25-17/h1-9,11,13H,10,12H2,(H2,24,30)(H,27,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50429613 (CHEMBL2334590) Show SMILES Cc1nc2ccc(Cl)cn2c1-c1ccnc(N)n1 Show InChI InChI=1S/C12H10ClN5/c1-7-11(9-4-5-15-12(14)17-9)18-6-8(13)2-3-10(18)16-7/h2-6H,1H3,(H2,14,15,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.57E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177040 (CHEMBL3814642) Show SMILES Clc1ccc2ncnc(NCCCc3ccccc3)c2c1 Show InChI InChI=1S/C17H16ClN3/c18-14-8-9-16-15(11-14)17(21-12-20-16)19-10-4-7-13-5-2-1-3-6-13/h1-3,5-6,8-9,11-12H,4,7,10H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177039 (CHEMBL3814308) Show SMILES C(Sc1nc(N2CCOCC2)c2sccc2n1)c1ccccc1 Show InChI InChI=1S/C17H17N3OS2/c1-2-4-13(5-3-1)12-23-17-18-14-6-11-22-15(14)16(19-17)20-7-9-21-10-8-20/h1-6,11H,7-10,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50259613 (CHEMBL467720 | sodium 6-(5-chloro-2-(2,4-dichlorob...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2Cl)n1 Show InChI InChI=1S/C20H14Cl3NO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human CYP2C9				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177038 (CHEMBL3814655) Show SMILES Clc1ccc2ncnc(NCCOc3ccccc3)c2c1 Show InChI InChI=1S/C16H14ClN3O/c17-12-6-7-15-14(10-12)16(20-11-19-15)18-8-9-21-13-4-2-1-3-5-13/h1-7,10-11H,8-9H2,(H,18,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50177032 (CHEMBL3814407) Show SMILES FC(F)(F)c1cc(Nc2nc3ccccc3s2)cc(c1)C(F)(F)F Show InChI InChI=1S/C15H8F6N2S/c16-14(17,18)8-5-9(15(19,20)21)7-10(6-8)22-13-23-11-3-1-2-4-12(11)24-13/h1-7H,(H,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50177031 (CHEMBL3814969) Show SMILES COc1cncc(c1)-c1cnn2ccc(NC3CCC(O)CC3)nc12 |(5.87,-6.24,;5.57,-5.05,;4.09,-4.62,;2.98,-5.68,;1.5,-5.26,;1.13,-3.76,;2.24,-2.7,;3.72,-3.12,;1.76,-1.24,;2.66,.02,;1.76,1.24,;.3,.77,;-1.03,1.55,;-2.38,.77,;-2.38,-.77,;-3.72,-1.53,;-3.72,-3.07,;-5.06,-3.84,;-5.06,-5.38,;-3.73,-6.15,;-3.74,-7.38,;-2.4,-5.39,;-2.39,-3.85,;-1.03,-1.55,;.3,-.77,)| Show InChI InChI=1S/C18H21N5O2/c1-25-15-8-12(9-19-10-15)16-11-20-23-7-6-17(22-18(16)23)21-13-2-4-14(24)5-3-13/h6-11,13-14,24H,2-5H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50177044 (CHEMBL3814695) Show SMILES COc1cc(Nc2ccn3ncc(-c4cccc(c4)C(N)=O)c3n2)cc(OC)c1OC Show InChI InChI=1S/C22H21N5O4/c1-29-17-10-15(11-18(30-2)20(17)31-3)25-19-7-8-27-22(26-19)16(12-24-27)13-5-4-6-14(9-13)21(23)28/h4-12H,1-3H3,(H2,23,28)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.17E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177037 (CHEMBL3814438) Show SMILES C(Cc1cccnc1)Nc1ccc2ncc(-c3cc4ccccc4s3)n2n1 Show InChI InChI=1S/C21H17N5S/c1-2-6-18-16(5-1)12-19(27-18)17-14-24-21-8-7-20(25-26(17)21)23-11-9-15-4-3-10-22-13-15/h1-8,10,12-14H,9,11H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM50177045 (CHEMBL3814733) Show SMILES COc1cc(ccc1O)-c1cnc2ccc(NCc3ccco3)nn12 Show InChI InChI=1S/C18H16N4O3/c1-24-16-9-12(4-5-15(16)23)14-11-20-18-7-6-17(21-22(14)18)19-10-13-3-2-8-25-13/h2-9,11,23H,10H2,1H3,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human PI3Kgamma using PIP2 as substrate by HTRF assay in presence of biotin-PIP3				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177036 (CHEMBL1528007) Show SMILES CN(Cc1ccccc1)c1ncnc2ccc(Br)cc12 Show InChI InChI=1S/C16H14BrN3/c1-20(10-12-5-3-2-4-6-12)16-14-9-13(17)7-8-15(14)18-11-19-16/h2-9,11H,10H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human CYP2C9				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177035 (CHEMBL3814774) Show SMILES Cc1nn(c2CCc3cnc(N)nc3-c12)-c1ccccc1 Show InChI InChI=1S/C16H15N5/c1-10-14-13(21(20-10)12-5-3-2-4-6-12)8-7-11-9-18-16(17)19-15(11)14/h2-6,9H,7-8H2,1H3,(H2,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50177034 (CHEMBL3813732) Show SMILES O=C(C1CCC=CC1)N1CCCC(C1)c1n[nH]c2ncccc12 |c:5| Show InChI InChI=1S/C18H22N4O/c23-18(13-6-2-1-3-7-13)22-11-5-8-14(12-22)16-15-9-4-10-19-17(15)21-20-16/h1-2,4,9-10,13-14H,3,5-8,11-12H2,(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.51E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development Curated by ChEMBL					Assay Description Inhibition of human full length recombinant His-tagged PIK3CD/PIK3R1 expressed in baculovirus expression system after 60 mins by LanthaScreen Eu bind...				J Med Chem 59: 4302-13 (2016) Article DOI: 10.1021/acs.jmedchem.5b01974 BindingDB Entry DOI: 10.7270/Q2DN46ZF
					More data for this Ligand-Target Pair
Tripeptidyl-peptidase 2 (Rattus norvegicus)	BDBM50121278 (3-Ethyl-2,3,10,10a-tetrahydro-pyrazino[1,2-a]indol...) Show SMILES CC[C@@H]1NC(=O)[C@@H]2Cc3ccccc3N2C1=O Show InChI InChI=1S/C13H14N2O2/c1-2-9-13(17)15-10-6-4-3-5-8(10)7-11(15)12(16)14-9/h3-6,9,11H,2,7H2,1H3,(H,14,16)/t9-,11-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research & Development Curated by ChEMBL					Assay Description Inhibitory activity of the compound against tripeptidyl peptidase II purified from rat liver				J Med Chem 45: 5303-10 (2002) BindingDB Entry DOI: 10.7270/Q2736Q7X
					More data for this Ligand-Target Pair
Prostaglandin F2-alpha receptor (Homo sapiens (Human))	BDBM50259611 (CHEMBL467114 | sodium 6-(5-chloro-2-(4-chloro-2-fl...) Show SMILES [O-]C(=O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1 Show InChI InChI=1S/C20H14Cl2FNO3/c21-14-6-7-19(27-11-12-4-5-15(22)10-17(12)23)13(8-14)9-16-2-1-3-18(24-16)20(25)26/h1-8,10H,9,11H2,(H,25,26)/p-1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of FP receptor				Bioorg Med Chem Lett 19: 2599-603 (2009) Article DOI: 10.1016/j.bmcl.2009.02.112 BindingDB Entry DOI: 10.7270/Q2HT2P68
					More data for this Ligand-Target Pair

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