Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of binding of the compound to GnRH receptor in human | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of gonadotropin-releasing hormone receptor in rhesus monkey | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Functional antagonism at the human GnRH receptor (PI turnover) | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Rattus norvegicus) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of binding of the compound to GnRH receptor in rat | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Functional antagonism at the rhesus monkey gonadotropin-releasing hormone receptor | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description In vitro inhibition of binding of the compound to gonadotropin-releasing hormone receptor in dog | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Rattus norvegicus) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Functional antagonism at GnRH receptor in rat (PI turnover) | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Gonadotropin-releasing hormone receptor (Homo sapiens (Human)) | BDBM50098391 ((S)-4-(2-(azetidin-2-yl)ethoxy)-7-chloro-2-oxo-N-(...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Functional antagonism at gonadotropin-releasing hormone receptor in dog (PI turnover) | J Med Chem 44: 917-22 (2001) BindingDB Entry DOI: 10.7270/Q2H70F3D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Estrogen receptor (Homo sapiens (Human)) | BDBM23420 (7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
Xavier University of Louisiana Curated by ChEMBL | Assay Description Displacement of fluorescent labeled ES2 from recombinant ERalpha | J Med Chem 53: 6153-63 (2010) Article DOI: 10.1021/jm100610w BindingDB Entry DOI: 10.7270/Q26973RB | |||||||||||
More data for this Ligand-Target Pair |