Compile Data Set for Download or QSAR

Found 62 hits with Last Name = 'sanders-bush' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50001775 ((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...) Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033872 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C22H29N3O/c1-4-5-7-14(2)24-22(26)16-10-18-17-8-6-9-19-21(17)15(12-23-19)11-20(18)25(3)13-16/h6,8-10,12,14,16,20,23H,4-5,7,11,13H2,1-3H3,(H,24,26)/t14-,16-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033869 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-6-13(2)23-21(25)15-9-17-16-7-5-8-18-20(16)14(11-22-18)10-19(17)24(3)12-15/h5,7-9,11,13,15,19,22H,4,6,10,12H2,1-3H3,(H,23,25)/t13-,15-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50024204 (1H-imidazo[4,5-c]pyridine derivative | 2N-[4,7-dim...) Show SMILES CN(C)S(=O)(=O)N[C@H]1C[C@H]2[C@@H](Cc3cn(C)c4cccc2c34)N(C)C1 Show InChI InChI=1S/C18H26N4O2S/c1-20(2)25(23,24)19-13-9-15-14-6-5-7-16-18(14)12(10-21(16)3)8-17(15)22(4)11-13/h5-7,10,13,15,17,19H,8-9,11H2,1-4H3/t13-,15+,17+/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50008224 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22| Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12-,14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM35256 ((S)-mianserin | Lerivon | MIANSERIN | MIANSERIN (+...) Show SMILES [H][C@]12CN(C)CCN1c1ccccc1Cc1ccccc21 |r| Show InChI InChI=1S/C18H20N2/c1-19-10-11-20-17-9-5-3-7-15(17)12-14-6-2-4-8-16(14)18(20)13-19/h2-9,18H,10-13H2,1H3/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033874 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC(CC)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-15(5-2)23-21(25)14-9-17-16-7-6-8-18-20(16)13(11-22-18)10-19(17)24(3)12-14/h6-9,11,14-15,19,22H,4-5,10,12H2,1-3H3,(H,23,25)/t14-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033873 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:25| Show InChI InChI=1S/C23H31N3O/c1-4-5-6-8-15(2)25-23(27)17-11-19-18-9-7-10-20-22(18)16(13-24-20)12-21(19)26(3)14-17/h7,9-11,13,15,17,21,24H,4-6,8,12,14H2,1-3H3,(H,25,27)/t15-,17-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033869 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-6-13(2)23-21(25)15-9-17-16-7-5-8-18-20(16)14(11-22-18)10-19(17)24(3)12-15/h5,7-9,11,13,15,19,22H,4,6,10,12H2,1-3H3,(H,23,25)/t13-,15-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033868 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22| Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12?,14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033870 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C22H29N3O/c1-4-5-7-14(2)24-22(26)16-10-18-17-8-6-9-19-21(17)15(12-23-19)11-20(18)25(3)13-16/h6,8-10,12,14,16,20,23H,4-5,7,11,13H2,1-3H3,(H,24,26)/t14?,16-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM21342 ((4R,7R)-N,N-diethyl-6-methyl-6,11-diazatetracyclo[...) Show SMILES [H][C@@]12Cc3c[nH]c4cccc(C1=C[C@H](CN2C)C(=O)N(CC)CC)c34 |c:12| Show InChI InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	5.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033874 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC(CC)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-15(5-2)23-21(25)14-9-17-16-7-6-8-18-20(16)13(11-22-18)10-19(17)24(3)12-14/h6-9,11,14-15,19,22H,4-5,10,12H2,1-3H3,(H,23,25)/t14-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033867 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-6-13(2)23-21(25)15-9-17-16-7-5-8-18-20(16)14(11-22-18)10-19(17)24(3)12-15/h5,7-9,11,13,15,19,22H,4,6,10,12H2,1-3H3,(H,23,25)/t13?,15-,19-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50008224 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22| Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12-,14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50033871 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:25| Show InChI InChI=1S/C23H31N3O/c1-4-5-6-8-15(2)25-23(27)17-11-19-18-9-7-10-20-22(18)16(13-24-20)12-21(19)26(3)14-17/h7,9-11,13,15,17,21,24H,4-6,8,12,14H2,1-3H3,(H,25,27)/t15?,17-,21-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 1A receptor by displacement of [3H]-8-OH-DPAT by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033872 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C22H29N3O/c1-4-5-7-14(2)24-22(26)16-10-18-17-8-6-9-19-21(17)15(12-23-19)11-20(18)25(3)13-16/h6,8-10,12,14,16,20,23H,4-5,7,11,13H2,1-3H3,(H,24,26)/t14-,16-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM21395 (3-(2-(4-(4-Fluorobenzoyl)piperidinol)ethyl)-2,4(1H...) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCn2c(=O)[nH]c3ccccc3c2=O)CC1 Show InChI InChI=1S/C22H22FN3O3/c23-17-7-5-15(6-8-17)20(27)16-9-11-25(12-10-16)13-14-26-21(28)18-3-1-2-4-19(18)24-22(26)29/h1-8,16H,9-14H2,(H,24,29)	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033868 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:22| Show InChI InChI=1S/C20H25N3O/c1-4-12(2)22-20(24)14-8-16-15-6-5-7-17-19(15)13(10-21-17)9-18(16)23(3)11-14/h5-8,10,12,14,18,21H,4,9,11H2,1-3H3,(H,22,24)/t12?,14-,18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033870 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:24| Show InChI InChI=1S/C22H29N3O/c1-4-5-7-14(2)24-22(26)16-10-18-17-8-6-9-19-21(17)15(12-23-19)11-20(18)25(3)13-16/h6,8-10,12,14,16,20,23H,4-5,7,11,13H2,1-3H3,(H,24,26)/t14?,16-,20-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50059890 (2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...) Show SMILES COc1c2OCCc2c(CCN)c2CCOc12 Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033873 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCC[C@@H](C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:25| Show InChI InChI=1S/C23H31N3O/c1-4-5-6-8-15(2)25-23(27)17-11-19-18-9-7-10-20-22(18)16(13-24-20)12-21(19)26(3)14-17/h7,9-11,13,15,17,21,24H,4-6,8,12,14H2,1-3H3,(H,25,27)/t15-,17-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50010859 (CHEMBL11 | IMIPRAMINE HYDROCHLORIDE | IMIPRAMINE P...) Show SMILES CN(C)CCCN1c2ccccc2CCc2ccccc12 Show InChI InChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033867 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:23| Show InChI InChI=1S/C21H27N3O/c1-4-6-13(2)23-21(25)15-9-17-16-7-5-8-18-20(16)14(11-22-18)10-19(17)24(3)12-15/h5,7-9,11,13,15,19,22H,4,6,10,12H2,1-3H3,(H,23,25)/t13?,15-,19-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50059893 (2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...) Show SMILES CCOc1c(OC)cc(CCN)cc1OC Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	177	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50059890 (2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...) Show SMILES COc1c2OCCc2c(CCN)c2CCOc12 Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	205	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]- rauwolscine radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059893 (2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...) Show SMILES CCOc1c(OC)cc(CCN)cc1OC Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	216	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50059890 (2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...) Show SMILES COc1c2OCCc2c(CCN)c2CCOc12 Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	302	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	303	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	311	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-rauwolscine radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059890 (2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...) Show SMILES COc1c2OCCc2c(CCN)c2CCOc12 Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	335	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50033871 ((6aR,9R)-7-Methyl-4,6,6a,7,8,9-hexahydro-indolo[4,...) Show SMILES CCCCCC(C)NC(=O)[C@H]1CN(C)[C@@H]2Cc3c[nH]c4cccc(C2=C1)c34 |c:25| Show InChI InChI=1S/C23H31N3O/c1-4-5-6-8-15(2)25-23(27)17-11-19-18-9-7-10-20-22(18)16(13-24-20)12-21(19)26(3)14-17/h7,9-11,13,15,17,21,24H,4-6,8,12,14H2,1-3H3,(H,25,27)/t15?,17-,21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	357	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Binding affinity was measured against 5-hydroxytryptamine 2A receptor by displacement of [3H]- ketanserin by lysergic acid amides				J Med Chem 38: 958-66 (1995) BindingDB Entry DOI: 10.7270/Q2NZ86N6
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	368	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	523	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	551	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50059893 (2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...) Show SMILES CCOc1c(OC)cc(CCN)cc1OC Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	555	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50059890 (2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...) Show SMILES COc1c2OCCc2c(CCN)c2CCOc12 Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	654	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	795	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2B receptor using [3H]-5-HT radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.11E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonist activity at cloned human 5-hydroxytryptamine 2C receptor using [3H]-mesulergine radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM25761 (Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...) Show SMILES CC(C)NCC(O)COc1cccc2ccccc12 Show InChI InChI=1S/C16H21NO2/c1-12(2)17-10-14(18)11-19-16-9-5-7-13-6-3-4-8-15(13)16/h3-9,12,14,17-18H,10-11H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059893 (2-(4-Ethoxy-3,5-dimethoxy-phenyl)-ethylamine | CHE...) Show SMILES CCOc1c(OC)cc(CCN)cc1OC Show InChI InChI=1S/C12H19NO3/c1-4-16-12-10(14-2)7-9(5-6-13)8-11(12)15-3/h7-8H,4-6,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059892 (2-(6,7-Dimethoxy-2,3-dihydro-benzofuran-4-yl)-ethy...) Show SMILES COc1cc(CCN)c2CCOc2c1OC Show InChI InChI=1S/C12H17NO3/c1-14-10-7-8(3-5-13)9-4-6-16-11(9)12(10)15-2/h7H,3-6,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM50001859 ((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM35938 (1-(p-chlorophenyl)-1-(2-pyridyl)-3-N,N-dimethylpro...) Show SMILES CN(C)CCC(c1ccc(Cl)cc1)c1ccccn1 Show InChI InChI=1S/C16H19ClN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	3.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059890 (2-(8-Methoxy-2,3,5,6-tetrahydro-benzo[1,2-b;5,4-b'...) Show SMILES COc1c2OCCc2c(CCN)c2CCOc12 Show InChI InChI=1S/C13H17NO3/c1-15-13-11-9(3-6-16-11)8(2-5-14)10-4-7-17-12(10)13/h2-7,14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Antagonist activity at cloned human 5-hydroxytryptamine 2A receptor using [3H]-Ketanserin radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Curated by PDSP Ki Database									J Pharmacol Exp Ther 247: 169-73 (1988) BindingDB Entry DOI: 10.7270/Q2ZS2V0B
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane | 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI InChI=1S/C11H17NO3/c1-13-9-6-8(4-5-12)7-10(14-2)11(9)15-3/h6-7H,4-5,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
					More data for this Ligand-Target Pair

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