BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2A' and Ligand = 'BDBM50059891'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by PDSP K_i Database									J Neurosci 9: 3482-90 (1989) BindingDB Entry DOI: 10.7270/Q2FX77Z2
Stanford University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [125I]DOI from rat 5HT2A receptor				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	551	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Agonist activity at cloned human 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopy				Bioorg Med Chem 16: 4661-9 (2008) Article DOI: 10.1016/j.bmc.2008.02.033 BindingDB Entry DOI: 10.7270/Q25D8RNZ
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Ability to displace [3H]-ketanserin from rat cortical homogenate 5-hydroxytryptamine 2A receptor				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Tested for its ability to activate phospholipase c by quantification of IP3 at cloned rat 5-hydroxytryptamine 2A receptor				J Med Chem 46: 3526-35 (2003) Article DOI: 10.1021/jm030064v BindingDB Entry DOI: 10.7270/Q20P0ZC1
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+4	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Activity at rat 5HT2A receptor assessed as 5HT-stimulated IP3 accumulation				J Med Chem 49: 4269-74 (2006) Article DOI: 10.1021/jm060272y BindingDB Entry DOI: 10.7270/Q2PC320K
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50059891 (1-amino-2-(3,4,5-trimethoxyphenyl)ethane \| 2-(3,4,...) Show SMILES COc1cc(CCN)cc(OC)c1OC Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Effect on phosphoinositide hydrolysis in NIH 3T3 fibroblast 5-hydroxytryptamine 2A receptor				J Med Chem 40: 2997-3008 (1997) Article DOI: 10.1021/jm970219x BindingDB Entry DOI: 10.7270/Q2RF5T50
Purdue University Curated by ChEMBL					More data for this Ligand-Target Pair