Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50385393 (CHEMBL2036415) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]A585539 from alpha7 nAChR from rat brain membrane with no cerebellum/cortex | Bioorg Med Chem 20: 3698-702 (2012) Article DOI: 10.1016/j.bmc.2012.04.056 BindingDB Entry DOI: 10.7270/Q22R3SQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat)) | BDBM50385392 (CHEMBL2036416) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]A585539 from alpha7 nAChR from rat brain membrane with no cerebellum/cortex | Bioorg Med Chem 20: 3698-702 (2012) Article DOI: 10.1016/j.bmc.2012.04.056 BindingDB Entry DOI: 10.7270/Q22R3SQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Growth hormone secretagogue receptor type 1 (Homo sapiens (Human)) | BDBM50341518 ((S)-6-(4-Fluorophenoxy)-3-((1-methylpiperidin-3-yl...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Inhibition of [125I]Ghrelin binding to human Ghrelin receptor expressed in CHO-K1 cells after 60 mins by liquid scintillation spectrometry | Bioorg Med Chem 19: 2368-72 (2011) Article DOI: 10.1016/j.bmc.2011.02.021 BindingDB Entry DOI: 10.7270/Q2Q81DDM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50385393 (CHEMBL2036415) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Johns Hopkins University School of Medicine Curated by ChEMBL | Assay Description Displacement of [3H]dofetilide from human ERG | Bioorg Med Chem 20: 3698-702 (2012) Article DOI: 10.1016/j.bmc.2012.04.056 BindingDB Entry DOI: 10.7270/Q22R3SQW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.620 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50061203 ((R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 0.690 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]PIPAG to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Transporter (Rattus norvegicus) | BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]NANM of sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50046732 ((R)-3-(4-Chloro-phenyl)-8-aza-bicyclo[3.2.1]octane...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50053648 ((R)-3-(4-Ethyl-phenyl)-8-aza-bicyclo[3.2.1]octane-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50451132 (CHEMBL2079586 | WIN-35428) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]NANM of sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50366564 (CHEMBL1790051 | CHEMBL83729 | WIN-35065-2) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50046736 ((R)-3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50053655 ((R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2....) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50046736 ((R)-3-(3-Iodo-phenyl)-8-methyl-8-aza-bicyclo[3.2.1...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50053655 ((R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50035738 ((R)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50367061 (NALORPHINE | NALORPHINE HYDROCHLORIDE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50053648 ((R)-3-(4-Ethyl-phenyl)-8-aza-bicyclo[3.2.1]octane-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM81982 (CAS_97-39-2 | DITOLYLGUANIDINE | DTG | Di-o-tolylg...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50053655 ((R)-3-(4-Ethyl-phenyl)-8-methyl-8-aza-bicyclo[3.2....) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50002238 ((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]PIPAG to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50367061 (NALORPHINE | NALORPHINE HYDROCHLORIDE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 93 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50002238 ((R)1-(4-Fluoro-phenyl)-4-[4-(5-fluoro-pyrimidin-2-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]3-PPP to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50053648 ((R)-3-(4-Ethyl-phenyl)-8-aza-bicyclo[3.2.1]octane-...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50061203 ((R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Rattus norvegicus (rat)) | BDBM50061203 ((R)-3-(4-Ethyl-3-iodo-phenyl)-8-aza-bicyclo[3.2.1]...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 329 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-WN 35,428 binding to dopamine transporter (DAT) in rat striatal tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 450 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 560 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50367061 (NALORPHINE | NALORPHINE HYDROCHLORIDE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 625 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]3-PPP to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50451132 (CHEMBL2079586 | WIN-35428) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 692 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50367061 (NALORPHINE | NALORPHINE HYDROCHLORIDE) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 735 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]PIPAG to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 780 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]PIPAG to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50451132 (CHEMBL2079586 | WIN-35428) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 835 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 868 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [125I]-PIPAG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Transporter (Rattus norvegicus) | BDBM50366564 (CHEMBL1790051 | CHEMBL83729 | WIN-35065-2) | Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 920 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]-nisoxatine binding to norepinephrine transporter (NET) in rat cortical tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]DTG to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Rattus norvegicus (rat)) | BDBM50084717 ((+)-(1R,2R,3S,5S)-methyl 3-(benzoyloxy)-8-methyl-8...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Research Triangle Institute Curated by ChEMBL | Assay Description In vitro inhibitory activity against radioligand [3H]paroxetine binding to serotonin transporter (5-HTT) in rat midbrain tissue | J Med Chem 40: 3861-4 (1998) Article DOI: 10.1021/jm970492z BindingDB Entry DOI: 10.7270/Q2GX4C7G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM83449 (1-(1-phenylcyclohexyl)piperidine;hydrochloride | M...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PubMed | n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]DTG to sigma binding site in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50004107 (1-(1-Thiophen-2-yl-cyclohexyl)-piperidine | CHEMBL...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]NANM of sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human)) | BDBM50019742 (9-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)-9...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse Curated by ChEMBL | Assay Description Inhibition of specific binding of [3H]DTG to sigma receptor in Guinea pig brain membranes | J Med Chem 35: 4683-9 (1993) BindingDB Entry DOI: 10.7270/Q20865XT | |||||||||||
More data for this Ligand-Target Pair |
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