BindingDB PrimarySearch

Found 491 hits with Last Name = 'schoenen' and Initial = 'fj'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029954 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470745 (CHEMBL286840) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	PDB Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Competitive inhibition of GST-tagged DYRK1A (unknown origin) expressed in Escherichia coli BL21(DE3) by Lineweaver-Burk plot analysis in presence of ...				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470752 (CHEMBL38328) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50097699 (CHEMBL3590195) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Displacement of radio-labeled U69,593 from rat kappa opioid receptor expressed in HEK293 cell membranes				Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470756 (CHEMBL37453) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM54817 (4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Displacement of radio-labeled U69,593 from rat kappa opioid receptor expressed in HEK293 cell membranes				Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50097703 (CHEMBL3590199) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Displacement of radio-labeled U69,593 from rat kappa opioid receptor expressed in HEK293 cell membranes				Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470750 (CHEMBL286291) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470731 (CHEMBL146946) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470736 (CHEMBL37029) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029955 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470740 (CHEMBL264851) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470754 (CHEMBL288928) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029951 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470743 (CHEMBL422578) Show SMILES CCOC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470725 (CHEMBL36318) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Rattus norvegicus (rat))	BDBM50097697 (CHEMBL3590193) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Displacement of radio-labeled U69,593 from rat kappa opioid receptor expressed in HEK293 cell membranes				Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470735 (CHEMBL287687) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(C)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470748 (CHEMBL36724 \| TCMDC-131880) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C#N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470739 (CHEMBL413274) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470727 (CHEMBL2093097) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470755 (CHEMBL36626) Show SMILES COC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470749 (CHEMBL34846) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)N(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	145	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470729 (CHEMBL284970) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(S)=N Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470751 (CHEMBL286391) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470730 (CHEMBL35213) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Dual specificity tyrosine-phosphorylation-regulated kinase 1B (Homo sapiens (Human))	BDBM100152 (7-methoxy-1-methyl-9H-beta-carboline;hydrochloride...) Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	166	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Competitive inhibition of GST-tagged DYRK1B (unknown origin) expressed in Escherichia coli BL21(DE3) by Lineweaver-Burk plot analysis in presence of ...				Bioorg Med Chem Lett 23: 3654-61 (2013) Article DOI: 10.1016/j.bmcl.2013.02.096 BindingDB Entry DOI: 10.7270/Q2M90B2B
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470738 (CHEMBL36728) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(N)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470737 (CHEMBL290191) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470726 (CHEMBL1169563) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	186	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470747 (CHEMBL38219) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)C#CC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	195	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	221	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM14361 ((R,S)-Rolipram \| 4-(3-cyclopentyloxy-4-methoxy-phe...) Show SMILES COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	224	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Sigma intracellular receptor 2 (Homo sapiens (Human))	BDBM50606398 (ML-246 \| Metarrestin \| Ml-246) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00204 BindingDB Entry DOI: 10.7270/Q2FN1B9R
TBA					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470728 (CHEMBL285532) Show SMILES CCCC(=O)N1CCC(C1)c1ccc(OC)c(OC2CCCC2)c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470733 (CHEMBL290805) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)S(C)(=O)=O Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029953 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-tet...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	282	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM54817 (4-[[(4-methylphenyl)sulfonylamino]methyl]-N-[2-[(p...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	306	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kansas Specialized Chemistry Center Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor (unknown origin)				Bioorg Med Chem 23: 3948-56 (2015) Article DOI: 10.1016/j.bmc.2014.12.033 BindingDB Entry DOI: 10.7270/Q2R49SJX
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470734 (CHEMBL287226) Show SMILES COc1ccc(cc1OC1CCCC1)C1CCN(C1)C(=O)C(C)C Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029957 ((7R,7aS)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	338	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257088 (CHEMBL4066784) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	415	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT2B receptor expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 60: 6364-6383 (2017) Article DOI: 10.1021/acs.jmedchem.7b00561 BindingDB Entry DOI: 10.7270/Q2DR2XXZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470746 (CHEMBL37386) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470732 (CHEMBL1169562) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H2 receptor (Homo sapiens (Human))	BDBM50257088 (CHEMBL4066784) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	443	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States. Curated by ChEMBL					Assay Description Displacement of [3H]Cimetidine from human H2 receptor expressed in HEK cell membranes after 90 mins by scintillation counting method				J Med Chem 60: 6364-6383 (2017) Article DOI: 10.1021/acs.jmedchem.7b00561 BindingDB Entry DOI: 10.7270/Q2DR2XXZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029956 (4-(3-Cyclopentyloxy-4-methoxy-benzyl)-imidazolidin...) Show SMILES COc1ccc(CC2CNC(=O)N2)cc1OC1CCCC1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	447	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50257088 (CHEMBL4066784) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	575	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health , 10 Center Drive, Bethesda, Maryland 20892-1800, United States. Curated by ChEMBL					Assay Description Displacement of [3H]Rauwolscine from human alpha2C receptor expressed in MDCK cell membranes after 90 mins by scintillation counting method				J Med Chem 60: 6364-6383 (2017) Article DOI: 10.1021/acs.jmedchem.7b00561 BindingDB Entry DOI: 10.7270/Q2DR2XXZ
					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50029952 ((7R,7aR)-7-(3-Cyclopentyloxy-4-methoxy-phenyl)-hex...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	583	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Wellcome Research Curated by ChEMBL					Assay Description Inhibition of human Phosphodiesterase 4B				J Med Chem 38: 4848-54 (1996) BindingDB Entry DOI: 10.7270/Q2DZ079X
Glaxo Wellcome Research Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470742 (CHEMBL35486) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM50470744 (CHEMBL36109) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	741	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Glaxo Research Institute Curated by ChEMBL					Assay Description Inhibition of cAMP hydrolysis by the human phosphodiesterase 4B enzyme				J Med Chem 38: 1505-10 (1995) Article DOI: 10.1021/jm00009a011 BindingDB Entry DOI: 10.7270/Q2833VRG
Glaxo Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair

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