Compile Data Set for Download or QSAR

Found 66 hits with Last Name = 'soloviev' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.150	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301220 (3-(2-Chloro-6-fluoro-3,5-dimethoxyphenyl)-1-methyl...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16ClFN4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.270	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301220 (3-(2-Chloro-6-fluoro-3,5-dimethoxyphenyl)-1-methyl...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16ClFN4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301220 (3-(2-Chloro-6-fluoro-3,5-dimethoxyphenyl)-1-methyl...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16ClFN4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301243 (3'-(2,6-Difluoro-3,5-dimethoxyphenyl)-1'-methyl-4'...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)C5(CC5)c4c3N(C)C2=O)c1F Show InChI InChI=1S/C20H18F2N4O4/c1-25-15-9(7-23-17-12(15)20(4-5-20)18(27)24-17)8-26(19(25)28)16-13(21)10(29-2)6-11(30-3)14(16)22/h6-7H,4-5,8H2,1-3H3,(H,23,24,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.790	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Homo sapiens (Human))	BDBM50566789 (CHEMBL4862283) Show SMILES COc1ccc2nc(sc2c1)N1CCC(CC1)C(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of JAK2 (unknown origin)				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM50566796 (CHEMBL4871581) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(cc4c3N(C)C2=O)-c2cnn(C)c2)c1F Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKA (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301192 (3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301192 (3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301216 (3-(2-Fluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(F)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17FN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301192 (3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50566796 (CHEMBL4871581) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(cc4c3N(C)C2=O)-c2cnn(C)c2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301216 (3-(2-Fluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(F)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17FN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301216 (3-(2-Fluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(F)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17FN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301191 (3-(2-Chloro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(Cl)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17ClN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301261 (3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-(2,3-difluo...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)Cc4c3N(C2=O)c2cccc(F)c2F)c1F Show InChI InChI=1S/C23H16F4N4O4/c1-34-14-7-15(35-2)19(27)21(18(14)26)30-9-10-8-28-22-11(6-16(32)29-22)20(10)31(23(30)33)13-5-3-4-12(24)17(13)25/h3-5,7-8H,6,9H2,1-2H3,(H,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301191 (3-(2-Chloro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(Cl)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17ClN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301191 (3-(2-Chloro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(Cl)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17ClN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50566796 (CHEMBL4871581) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(cc4c3N(C)C2=O)-c2cnn(C)c2)c1F Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of AURKB (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50566796 (CHEMBL4871581) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(cc4c3N(C)C2=O)-c2cnn(C)c2)c1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-KIT (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301023 (3-(3,5-Dimethoxyphenyl)-1-methyl-1,3,4,7-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H18N4O3/c1-21-16-11(9-20-17-15(16)4-5-19-17)10-22(18(21)23)12-6-13(24-2)8-14(7-12)25-3/h4-9H,10H2,1-3H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566791 (CHEMBL4874869) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)Cc4c3N(CCO)C2=O)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301023 (3-(3,5-Dimethoxyphenyl)-1-methyl-1,3,4,7-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H18N4O3/c1-21-16-11(9-20-17-15(16)4-5-19-17)10-22(18(21)23)12-6-13(24-2)8-14(7-12)25-3/h4-9H,10H2,1-3H3,(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50566796 (CHEMBL4871581) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]c(cc4c3N(C)C2=O)-c2cnn(C)c2)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFR-beta (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566789 (CHEMBL4862283) Show SMILES COc1ccc2nc(sc2c1)N1CCC(CC1)C(CC#N)n1cc(cn1)-c1ncnc2[nH]ccc12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301023 (3-(3,5-Dimethoxyphenyl)-1-methyl-1,3,4,7-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H18N4O3/c1-21-16-11(9-20-17-15(16)4-5-19-17)10-22(18(21)23)12-6-13(24-2)8-14(7-12)25-3/h4-9H,10H2,1-3H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301306 (4-[3-(2,6-difluoro-3,5-dimethoxyphenyl)-2,8-dioxo-...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)Cc4c3N(C2=O)c2ccc(cc2)C#N)c1F Show InChI InChI=1S/C24H17F2N5O4/c1-34-16-8-17(35-2)20(26)22(19(16)25)30-11-13-10-28-23-15(7-18(32)29-23)21(13)31(24(30)33)14-5-3-12(9-27)4-6-14/h3-6,8,10H,7,11H2,1-2H3,(H,28,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566794 (CHEMBL4858423) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)C(C)(C)c4c3N(C)C2=O)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-KIT (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566793 (CHEMBL4848530) Show SMILES CCN1C(=O)N(Cc2cnc3NC(=O)C4(CC4)c3c12)c1c(F)c(OC)cc(OC)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566795 (CHEMBL4873003) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)C5(CCN(C)CC5)c4c3N(C)C2=O)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Mus musculus)	BDBM301310 (3-(2,6-difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(mo...) Show SMILES CCN1C(=O)N(Cc2cnc3[nH]c(CN4CCOCC4)cc3c12)c1c(F)c(OC)cc(OC)c1F Show InChI InChI=1S/C24H27F2N5O4/c1-4-30-21-14(11-27-23-16(21)9-15(28-23)13-29-5-7-35-8-6-29)12-31(24(30)32)22-19(25)17(33-2)10-18(34-3)20(22)26/h9-11H,4-8,12-13H2,1-3H3,(H,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In vivo inhibition of FGFR2 in po dosed SCID mouse xenografted with human KATO III stomach cancer cell line administered as single dose and measured ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566792 (CHEMBL4866178) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4NC(=O)Cc4c3N(CCN3CCOCC3)C2=O)c1F Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301220 (3-(2-Chloro-6-fluoro-3,5-dimethoxyphenyl)-1-methyl...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16ClFN4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM301193 (3-(2,4-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c(Cl)c(OC)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)11-6-12(26-2)14(20)16(27-3)13(11)19/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 1 (Homo sapiens (Human))	BDBM50566790 (CHEMBL4861534) Show SMILES COc1cc(CCc2cnc3[nH]ccc3c2)cc(OC)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR1 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301216 (3-(2-Fluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(F)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17FN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 2 (Homo sapiens (Human))	BDBM301193 (3-(2,4-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c(Cl)c(OC)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)11-6-12(26-2)14(20)16(27-3)13(11)19/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR2 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Fibroblast growth factor receptor 3 (Homo sapiens (Human))	BDBM301193 (3-(2,4-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c(Cl)c(OC)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)11-6-12(26-2)14(20)16(27-3)13(11)19/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	108	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human FGFR3 using biotinylated-EQEDEPEGDYFEWLE peptide as substrate incubated for 1 hr in presence of ATP by FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301191 (3-(2-Chloro-3,5-dimethoxyphenyl)-1-methyl-1,3,4,7-...) Show SMILES COc1cc(OC)c(Cl)c(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H17ClN4O3/c1-22-16-10(8-21-17-12(16)4-5-20-17)9-23(18(22)24)13-6-11(25-2)7-14(26-3)15(13)19/h4-8H,9H2,1-3H3,(H,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	131	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301192 (3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(Cl)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1Cl Show InChI InChI=1S/C18H16Cl2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301233 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-3,4,7...) Show SMILES CCN1C(=O)N(Cc2cnc3NC(=O)Cc3c12)c1c(F)c(OC)cc(OC)c1F Show InChI InChI=1S/C19H18F2N4O4/c1-4-24-16-9(7-22-18-10(16)5-13(26)23-18)8-25(19(24)27)17-14(20)11(28-2)6-12(29-3)15(17)21/h6-7H,4-5,8H2,1-3H3,(H,22,23,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	288	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of VEGFR2 (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	406	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of PDGFR-beta (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM301233 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-3,4,7...) Show SMILES CCN1C(=O)N(Cc2cnc3NC(=O)Cc3c12)c1c(F)c(OC)cc(OC)c1F Show InChI InChI=1S/C19H18F2N4O4/c1-4-24-16-9(7-22-18-10(16)5-13(26)23-18)8-25(19(24)27)17-14(20)11(28-2)6-12(29-3)15(17)21/h6-7H,4-5,8H2,1-3H3,(H,22,23,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-KIT (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM301023 (3-(3,5-Dimethoxyphenyl)-1-methyl-1,3,4,7-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)N1Cc2cnc3[nH]ccc3c2N(C)C1=O Show InChI InChI=1S/C18H18N4O3/c1-21-16-11(9-20-17-15(16)4-5-19-17)10-22(18(21)23)12-6-13(24-2)8-14(7-12)25-3/h4-9H,10H2,1-3H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	452	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Homo sapiens (Human))	BDBM301217 (3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-methyl-1,3,...) Show SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ccc4c3N(C)C2=O)c1F Show InChI InChI=1S/C18H16F2N4O3/c1-23-15-9(7-22-17-10(15)4-5-21-17)8-24(18(23)25)16-13(19)11(26-2)6-12(27-3)14(16)20/h4-7H,8H2,1-3H3,(H,21,22)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	458	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of TRKA (unknown origin) incubated for 90 mins in presence of ATP by HTRF assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50566790 (CHEMBL4861534) Show SMILES COc1cc(CCc2cnc3[nH]ccc3c2)cc(OC)c1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human recombinant N-terminal His6-tagged VEGFR2 expressed in baculovirus infected Sf21insect cells using biotin-labeled EQEDEPEGDYFEWLE...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00713 BindingDB Entry DOI: 10.7270/Q2S1867R
					More data for this Ligand-Target Pair

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