Compile Data Set for Download or QSAR

Found 177 hits with Last Name = 'somers' and Initial = 'f'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547789 (CHEMBL4794209) Show SMILES C[C@@H]1CCN(C[C@H]1c1cc(nc2ncnn12)C(F)F)C(=O)c1ccc2occc2c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547752 (CHEMBL4797113) Show SMILES CC1CCN(CC1c1cc(nc2ncnn12)C(F)F)C(=O)c1ccc2occc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547793 (CHEMBL4741218) Show SMILES C[C@@H]1CCN(C[C@H]1c1cc(nc2ncnn12)C(F)F)c1cc(ccn1)-c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547769 (CHEMBL4758144) Show SMILES CS(=O)(=O)n1ccc2cc(ccc12)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547790 (CHEMBL4754478) Show SMILES COc1ccc(cc1OC)C(=O)N1CC[C@@H](C)[C@@H](C1)c1cc(nc2ncnn12)C(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547765 (CHEMBL4783572) Show SMILES CC(=O)n1ccc2cc(ccc12)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547766 (CHEMBL4788385) Show SMILES CS(=O)(=O)n1ccc2cc(ccc12)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547751 (CHEMBL4755779) Show SMILES FC(F)c1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547775 (CHEMBL4742646) Show SMILES Cc1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547767 (CHEMBL4761967) Show SMILES O=C(N1CCC[C@@H](C1)c1ccnc2ncnn12)c1cc2CCCCc2s1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547778 (CHEMBL4761452) Show SMILES O=C(N1CCCC(C1)c1cc(nc2ncnn12)C#N)c1cc2CCCCc2s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547764 (CHEMBL4740457) Show SMILES O=C(N1CCCC(C1)c1ccnc2ncnn12)c1ccc2occc2c1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547787 (CHEMBL4797527) Show SMILES Cc1cc(CN2CCC[C@@H](C2)c2cc(nc3ncnn23)C(F)F)cc(Cl)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547780 (CHEMBL4751598) Show SMILES FC(F)c1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2nccc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547782 (CHEMBL4745282) Show SMILES O=C(N1CCCC(C1)c1ccnc2[nH]ccc12)c1cc2CCCCc2s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547753 (CHEMBL4744076) Show SMILES COc1ccc(cc1OC)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547763 (CHEMBL4793775) Show SMILES O=C(N1CCC[C@@H](C1)c1ccnc2ncnn12)c1ccc2OCCOc2c1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547779 (CHEMBL4793092) Show SMILES FC(F)(F)c1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547760 (CHEMBL4763230) Show SMILES COc1ccc(cc1)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM50547769 (CHEMBL4758144) Show SMILES CS(=O)(=O)n1ccc2cc(ccc12)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547751 (CHEMBL4755779) Show SMILES FC(F)c1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547750 (CHEMBL4800314) Show SMILES COc1cc(cc(OC)c1OC)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547788 (CHEMBL4785227) Show SMILES Cc1cc(CN2CCC[C@@H](C2)c2cc(nc3ncnn23)C(F)F)cc(C)n1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547759 (CHEMBL4761206) Show SMILES COc1cccc(c1)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50547780 (CHEMBL4751598) Show SMILES FC(F)c1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2nccc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3B expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547772 (CHEMBL4758400) Show SMILES CN1CCN(CC1c1ccnc2ncnn12)C(=O)c1cc2CCCCc2s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547768 (CHEMBL4786145) Show SMILES CS(=O)(=O)n1ccc2cc(ccc12)C(=O)N1CCC[C@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547776 (CHEMBL4764406) Show SMILES CC(C)c1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547767 (CHEMBL4761967) Show SMILES O=C(N1CCC[C@@H](C1)c1ccnc2ncnn12)c1cc2CCCCc2s1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547770 (CHEMBL4796896) Show SMILES O=C(N1CCO[C@@H](C1)c1ccnc2ncnn12)c1cc2CCCCc2s1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	91	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM50547765 (CHEMBL4783572) Show SMILES CC(=O)n1ccc2cc(ccc12)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM50547783 (CHEMBL4757440) Show SMILES Cc1nc2nc(C)cc(C3CCCN(C3)C(=O)c3cc4CCCCc4s3)n2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM50547766 (CHEMBL4788385) Show SMILES CS(=O)(=O)n1ccc2cc(ccc12)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547791 (CHEMBL4798804) Show SMILES CNC(=O)c1ccnc(c1)N1CCC(C)C(C1)c1cc(nc2ncnn12)C(F)F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547775 (CHEMBL4742646) Show SMILES Cc1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	112	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (Homo sapiens (Human))	BDBM50547777 (CHEMBL4746828) Show SMILES COc1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3B expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547792 (CHEMBL4796661) Show SMILES C[C@@H]1CCN(C[C@H]1c1cc(nc2ncnn12)C(F)F)c1cc(ccn1)C(C)(C)C |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	155	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547770 (CHEMBL4796896) Show SMILES O=C(N1CCO[C@@H](C1)c1ccnc2ncnn12)c1cc2CCCCc2s1 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547777 (CHEMBL4746828) Show SMILES COc1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Rattus norvegicus)	BDBM50363009 (CHEMBL1946412) Show SMILES CC(C)NC1=Nc2cc(Br)ccc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C10H12BrN3O2S/c1-6(2)12-10-13-8-5-7(11)3-4-9(8)17(15,16)14-10/h3-6H,1-2H3,(H2,12,13,14)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Li£ge Curated by ChEMBL					Assay Description Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretion				J Med Chem 54: 8353-61 (2011) Article DOI: 10.1021/jm200786z BindingDB Entry DOI: 10.7270/Q2WQ047Q
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM50547775 (CHEMBL4742646) Show SMILES Cc1cc(C2CCCN(C2)C(=O)c2cc3CCCCc3s2)n2ncnc2n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Rattus norvegicus)	BDBM50363013 (CHEMBL191539) Show SMILES COc1cc2c(cc1Cl)N=C(NC(C)C)NS2(=O)=O |t:10| Show InChI InChI=1S/C11H14ClN3O3S/c1-6(2)13-11-14-8-4-7(12)9(18-3)5-10(8)19(16,17)15-11/h4-6H,1-3H3,(H2,13,14,15)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Li£ge Curated by ChEMBL					Assay Description Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretion				J Med Chem 54: 8353-61 (2011) Article DOI: 10.1021/jm200786z BindingDB Entry DOI: 10.7270/Q2WQ047Q
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547756 (CHEMBL4746465) Show SMILES O=C(C1CC1)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547774 (CHEMBL4762723) Show SMILES O=C(N1CCCCC(C1)c1ccnc2ncnn12)c1cc2CCCCc2s1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8 (Rattus norvegicus)	BDBM50363006 (CHEMBL363989) Show SMILES CC(C)NC1=Nc2cc(Cl)c(Cl)cc2S(=O)(=O)N1 |t:4| Show InChI InChI=1S/C10H11Cl2N3O2S/c1-5(2)13-10-14-8-3-6(11)7(12)4-9(8)18(16,17)15-10/h3-5H,1-2H3,(H2,13,14,15)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Li£ge Curated by ChEMBL					Assay Description Activation of SUR1 in rat pancreatic islets assessed as inhibition of glucose-induced insulin secretion				J Med Chem 54: 8353-61 (2011) Article DOI: 10.1021/jm200786z BindingDB Entry DOI: 10.7270/Q2WQ047Q
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547769 (CHEMBL4758144) Show SMILES CS(=O)(=O)n1ccc2cc(ccc12)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	282	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Rattus norvegicus (rat))	BDBM50547767 (CHEMBL4761967) Show SMILES O=C(N1CCC[C@@H](C1)c1ccnc2ncnn12)c1cc2CCCCc2s1 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	288	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged rat recombinant PDE10A2 expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547762 (CHEMBL4799257) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)N1CCC[C@@H](C1)c1ccnc2ncnn12 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	324	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A (Homo sapiens (Human))	BDBM50547765 (CHEMBL4783572) Show SMILES CC(=O)n1ccc2cc(ccc12)C(=O)N1CCCC(C1)c1ccnc2ncnn12 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	331	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE3A expressed in Sf9 cells in presence of [3H]-cAMP and cAMP incubated for 60 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50547755 (CHEMBL4777378) Show SMILES O=C(N1CCC[C@@H](C1)c1ccnc2ncnn12)c1ccccc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	339	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of 6xHis-tagged human recombinant PDE2A expressed in Sf9 cells in presence of [3H]-cGMP and cGMP incubated for 40 mins by scintillation co...				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01272 BindingDB Entry DOI: 10.7270/Q22Z194S
					More data for this Ligand-Target Pair

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