BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 353 hits with Last Name = 'srinivas' and Initial = 'r'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581348
PNG
(US11504381, Compound 31 | US11548866, Compound 31)
Show SMILES Nc1cc(Cl)cnc1N1[C@@H](CC2CCCC2)CN(C[C@H]1c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
300n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581348
PNG
(US11504381, Compound 31 | US11548866, Compound 31)
Show SMILES Nc1cc(Cl)cnc1N1[C@@H](CC2CCCC2)CN(C[C@H]1c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
300n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581346
PNG
(US11504381, Compound 29)
Show SMILES CC(C)C[C@H]1CN(CC(N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
500n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM582884
PNG
(US11548866, Compound 29)
Show SMILES CC(C)C[C@H]1CN(C[C@H](N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
500n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581347
PNG
(US11504381, Compound 30 | US11548866, Compound 30)
Show SMILES CC(C)(C)C[C@H]1CN(C[C@H](N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
800n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581347
PNG
(US11504381, Compound 30 | US11548866, Compound 30)
Show SMILES CC(C)(C)C[C@H]1CN(C[C@H](N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
800n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581338
PNG
(US11504381, Compound 21 | US11548866, Compound 21)
Show SMILES CC(C)C[C@H]1CN(C[C@H](N1c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.50E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581338
PNG
(US11504381, Compound 21 | US11548866, Compound 21)
Show SMILES CC(C)C[C@H]1CN(C[C@H](N1c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.50E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581333
PNG
(US11504381, Compound 16 | US11548866, Compound 16)
Show SMILES CC[C@H]1CN(C[C@H](N1c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581333
PNG
(US11504381, Compound 16 | US11548866, Compound 16)
Show SMILES CC[C@H]1CN(C[C@H](N1c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
4.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581337
PNG
(US11504381, Compound 20 | US11548866, Compound 20)
Show SMILES OC(=O)CC(=O)N1C[C@H](C2CC2)N([C@@H](C1)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581337
PNG
(US11504381, Compound 20 | US11548866, Compound 20)
Show SMILES OC(=O)CC(=O)N1C[C@H](C2CC2)N([C@@H](C1)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581332
PNG
(US11504381, Compound 15 | US11548866, Compound 15)
Show SMILES C[C@H]1CN(C[C@H](N1c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581332
PNG
(US11504381, Compound 15 | US11548866, Compound 15)
Show SMILES C[C@H]1CN(C[C@H](N1c1ccc(Cl)cc1)c1ccc(Cl)cc1)C(=O)CC(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9.00E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581325
PNG
(US11504381, Compound 8 | US11548866, Compound 8)
Show SMILES CC(C)C1CN(C(CN1C(=O)CC(O)=O)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581325
PNG
(US11504381, Compound 8 | US11548866, Compound 8)
Show SMILES CC(C)C1CN(C(CN1C(=O)CC(O)=O)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581330
PNG
(US11504381, Compound 13 | US11548866, Compound 13)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)c1cnccc1C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.30E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581330
PNG
(US11504381, Compound 13 | US11548866, Compound 13)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)c1cnccc1C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.30E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581328
PNG
(US11504381, Compound 11 | US11548866, Compound 11)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)NCC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581328
PNG
(US11504381, Compound 11 | US11548866, Compound 11)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)NCC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581324
PNG
(US11504381, Compound 7 | US11548866, Compound 7)
Show SMILES Nc1cc(Cl)ccc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581324
PNG
(US11504381, Compound 7 | US11548866, Compound 7)
Show SMILES Nc1cc(Cl)ccc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
1.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581343
PNG
(US11504381, Compound 26 | US11548866, Compound 26)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1CC(C1)C(O)=O |(-4.67,-3.21,;-3.33,-3.98,;-3.33,-5.52,;-2,-6.29,;-2,-7.83,;-.67,-5.52,;-.67,-3.98,;-2,-3.21,;-2,-1.67,;-3.33,-.9,;-3.33,.64,;-2,1.41,;-.67,.64,;-.67,-.9,;.67,-1.67,;.67,-3.21,;2,-3.98,;3.33,-3.21,;4.67,-3.98,;3.33,-1.67,;2,-.9,;-2,2.95,;-3.33,3.72,;-.67,3.72,;.87,3.72,;.87,5.26,;-.67,5.26,;1.96,6.35,;3.45,5.95,;1.56,7.83,)|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.20E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581343
PNG
(US11504381, Compound 26 | US11548866, Compound 26)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1CC(C1)C(O)=O |(-4.67,-3.21,;-3.33,-3.98,;-3.33,-5.52,;-2,-6.29,;-2,-7.83,;-.67,-5.52,;-.67,-3.98,;-2,-3.21,;-2,-1.67,;-3.33,-.9,;-3.33,.64,;-2,1.41,;-.67,.64,;-.67,-.9,;.67,-1.67,;.67,-3.21,;2,-3.98,;3.33,-3.21,;4.67,-3.98,;3.33,-1.67,;2,-.9,;-2,2.95,;-3.33,3.72,;-.67,3.72,;.87,3.72,;.87,5.26,;-.67,5.26,;1.96,6.35,;3.45,5.95,;1.56,7.83,)|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.20E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581331
PNG
(US11504381, Compound 14 | US11548866, Compound 14)
Show SMILES CC(C)CC1CN(C(CN1C(=O)CC(O)=O)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.30E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581331
PNG
(US11504381, Compound 14 | US11548866, Compound 14)
Show SMILES CC(C)CC1CN(C(CN1C(=O)CC(O)=O)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.30E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581322
PNG
(US11504381, Compound 5)
Show SMILES Nc1cc(cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CC(O)=O)C(F)(F)F
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM582720
PNG
(US11548866, Compound 5)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581320
PNG
(US11504381, Compound 3 | US11548866, Compound 3)
Show SMILES Nc1cc(ccc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CC(O)=O)C(F)(F)F
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.90E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581320
PNG
(US11504381, Compound 3 | US11548866, Compound 3)
Show SMILES Nc1cc(ccc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CC(O)=O)C(F)(F)F
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
2.90E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM582878
PNG
(US11548866, Compound 24)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1C[C@@H]1C(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.40E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581335
PNG
(US11504381, Compound 18 | US11504381, Compound 24 ...)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1CC1C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.40E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581344
PNG
(US11504381, Compound 27 | US11548866, Compound 27)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)c1cccc(c1)C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581344
PNG
(US11504381, Compound 27 | US11548866, Compound 27)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)c1cccc(c1)C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581327
PNG
(US11504381, Compound 10 | US11548866, Compound 10)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CCC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.90E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581327
PNG
(US11504381, Compound 10 | US11548866, Compound 10)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CCC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
3.90E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581345
PNG
(US11504381, Compound 28 | US11548866, Compound 28)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)c1ccc(cc1)C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
4.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581345
PNG
(US11504381, Compound 28 | US11548866, Compound 28)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)c1ccc(cc1)C(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
4.60E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581334
PNG
(US11504381, Compound 17 | US11548866, Compound 17)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CCCC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.00E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581334
PNG
(US11504381, Compound 17 | US11548866, Compound 17)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)CCCC(O)=O
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.00E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581342
PNG
(US11504381, Compound 25 | US11548866, Compound 25)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1CC[C@@H]1C(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581342
PNG
(US11504381, Compound 25 | US11548866, Compound 25)
Show SMILES Nc1cc(Cl)cnc1N1CCN(CC1c1ccc(Cl)cc1)C(=O)C1CC[C@@H]1C(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581339
PNG
(US11504381, Compound 22 | US11548866, Compound 22)
Show SMILES CNC(=O)CC(=O)N1CCN(C(C1)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581339
PNG
(US11504381, Compound 22 | US11548866, Compound 22)
Show SMILES CNC(=O)CC(=O)N1CCN(C(C1)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.10E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581323
PNG
(US11504381, Compound 6 | US11548866, Compound 6)
Show SMILES CC1CN(C(CN1C(=O)CC(O)=O)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581323
PNG
(US11504381, Compound 6 | US11548866, Compound 6)
Show SMILES CC1CN(C(CN1C(=O)CC(O)=O)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
6.80E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581340
PNG
(US11504381, Compound 23 | US11548866, Compound 23)
Show SMILES CNC(=O)CN1CCN(C(C1)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
7.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581340
PNG
(US11504381, Compound 23 | US11548866, Compound 23)
Show SMILES CNC(=O)CN1CCN(C(C1)c1ccc(Cl)cc1)c1ncc(Cl)cc1N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
7.50E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581318
PNG
(US11504381, Compound 1 | US11548866, Compound 1)
Show SMILES Nc1cc(cnc1N1CCN(CC(O)=O)CC1c1ccc(Cl)cc1)C(F)(F)F
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9.20E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2JM2FG6
More data for this
Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2


(Homo sapiens (Human))
BDBM581318
PNG
(US11504381, Compound 1 | US11548866, Compound 1)
Show SMILES Nc1cc(cnc1N1CCN(CC(O)=O)CC1c1ccc(Cl)cc1)C(F)(F)F
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
9.20E+4n/an/an/an/an/an/an/an/a


TBA

Assay Description
The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2PN99GS
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 353 total )  |  Next  |  Last  >>
Jump to: