Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'E3 ubiquitin-protein ligase Mdm2' and Ligand = 'BDBM582884'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM582884 (US11548866, Compound 29) Show SMILES CC(C)C[C@H]1CN(C[C@H](N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The compounds binding to MDM2 were determined by a quantitative fluorescence polarization binding assay using a recombinant MDM2 protein and fluoresc...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN99GS
					More data for this Ligand-Target Pair
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human))	BDBM582884 (US11548866, Compound 29) Show SMILES CC(C)C[C@H]1CN(C[C@H](N1c1ncc(Cl)cc1N)c1ccc(Cl)cc1)C(=O)CC(O)=O |r| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description ITC experiments were run on a Malvern MicroCal Auto-ITC200 or ITC200 machine. Titration experiments were run in 20 mM Phosphate, 150 mM NaCl and 1 mM...				Citation and Details BindingDB Entry DOI: 10.7270/Q2PN99GS
					More data for this Ligand-Target Pair