Compile Data Set for Download or QSAR

Found 342 hits with Last Name = 'stansfield' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384714 (CHEMBL2037200) Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Reversible inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM283216 (4-[2-(4-amino-piperidin-1-yl)-5- (3-fluoro-4-metho...) Show SMILES COc1ccc(cc1F)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C24H23F2N5O2/c1-30-23(32)21(14-5-6-20(33-2)19(26)11-14)22(15-3-4-16(13-27)18(25)12-15)29-24(30)31-9-7-17(28)8-10-31/h3-6,11-12,17H,7-10,28H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM501809 (4-[6-(4-amino-piperidin-1-yl)-4- methyl-5-oxo-3-p...) Show SMILES Cc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)c(=O)n1C)-c1ccc(C#N)c(F)c1 Show InChI InChI=1S/C24H24FN5O/c1-15-3-5-16(6-4-15)22-21(17-7-8-18(14-26)20(25)13-17)28-23(24(31)29(22)2)30-11-9-19(27)10-12-30/h3-8,13,19H,9-12,27H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264020 (2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(cc1)C#N Show InChI InChI=1S/C17H12N4O3/c18-10-12-1-3-13(4-2-12)11-24-16-6-8-20-21(16)15-9-14(17(22)23)5-7-19-15/h1-9H,11H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503504 (CHEMBL4444902 | US10626103, Example 54) Show SMILES CN[C@H]1CCN(C1)C(=O)c1nc(-c2ccc(C#N)c(F)c2)n(c1C)-c1ccc2nn(C)c(Cl)c2c1 |r| Show InChI InChI=1S/C25H23ClFN7O/c1-14-22(25(35)33-9-8-17(13-33)29-2)30-24(15-4-5-16(12-28)20(27)10-15)34(14)18-6-7-21-19(11-18)23(26)32(3)31-21/h4-7,10-11,17,29H,8-9,13H2,1-3H3/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM283129 (4-[2-(4-amino-piperidin-1-yl)-5- (4-methoxyphenyl)...) Show SMILES COc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H25N5O2/c1-28-23(30)21(17-7-9-20(31-2)10-8-17)22(18-5-3-16(15-25)4-6-18)27-24(28)29-13-11-19(26)12-14-29/h3-10,19H,11-14,26H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM283200 (4-[2-(4-amino-piperidin-1-yl)-5-(4- methoxyphenyl)...) Show SMILES COc1ccc(cc1F)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H24FN5O2/c1-29-23(31)21(17-7-8-20(32-2)19(25)13-17)22(16-5-3-15(14-26)4-6-16)28-24(29)30-11-9-18(27)10-12-30/h3-8,13,18H,9-12,27H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264012 (2-[5-[(4-chloro-2- methoxyphenyl)methoxy]pyrazol- ...) Show SMILES COc1cc(Cl)ccc1COc1ccnn1-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C17H14ClN3O4/c1-24-14-9-13(18)3-2-12(14)10-25-16-5-7-20-21(16)15-8-11(17(22)23)4-6-19-15/h2-9H,10H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264025 (2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...) Show SMILES CN(C)CCc1cnn(c1OCc1ccc(F)cc1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C20H21FN4O3/c1-24(2)10-8-16-12-23-25(18-11-15(20(26)27)7-9-22-18)19(16)28-13-14-3-5-17(21)6-4-14/h3-7,9,11-12H,8,10,13H2,1-2H3,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant CK2alpha by radiometric assay				J Med Chem 54: 635-54 (2011) Article DOI: 10.1021/jm101251q BindingDB Entry DOI: 10.7270/Q2J67H7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50335638 (5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...) Show SMILES OC(=O)c1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc21 Show InChI InChI=1S/C19H12ClN3O2/c20-12-2-1-3-13(9-12)22-18-15-6-7-21-10-16(15)14-5-4-11(19(24)25)8-17(14)23-18/h1-10H,(H,22,23)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Cylene Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human recombinant CK2alpha at enzyme-substrate complex by radiometric assay				J Med Chem 54: 635-54 (2011) Article DOI: 10.1021/jm101251q BindingDB Entry DOI: 10.7270/Q2J67H7N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM263974 (2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccccc1 Show InChI InChI=1S/C16H13N3O3/c20-16(21)13-6-8-17-14(10-13)19-15(7-9-18-19)22-11-12-4-2-1-3-5-12/h1-10H,11H2,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503514 (CHEMBL4522607 | US10626103, Example 55) Show SMILES CN[C@@H]1CCCN(C1)C(=O)c1nc(-c2ccc(C#N)c(F)c2)n(c1C)-c1ccc2nn(C)c(Cl)c2c1 |r| Show InChI InChI=1S/C26H25ClFN7O/c1-15-23(26(36)34-10-4-5-18(14-34)30-2)31-25(16-6-7-17(13-29)21(28)11-16)35(15)19-8-9-22-20(12-19)24(27)33(3)32-22/h6-9,11-12,18,30H,4-5,10,14H2,1-3H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM501778 (4-[6-(4-aminopiperidin-1-yl)-4- methyl-3-(4-methy...) Show SMILES Cc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)c(=O)n1C)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H25N5O/c1-16-3-7-19(8-4-16)22-21(18-9-5-17(15-25)6-10-18)27-23(24(30)28(22)2)29-13-11-20(26)12-14-29/h3-10,20H,11-14,26H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM283128 (4-(2-(4-aminopiperidin-1-yl)- 1-methyl-6-oxo-5-p-t...) Show SMILES Cc1ccc(cc1)-c1c(nc(N2CCC(N)CC2)n(C)c1=O)-c1ccc(cc1)C#N Show InChI InChI=1S/C24H25N5O/c1-16-3-7-18(8-4-16)21-22(19-9-5-17(15-25)6-10-19)27-24(28(2)23(21)30)29-13-11-20(26)12-14-29/h3-10,20H,11-14,26H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50554230 (CHEMBL4748670) Show SMILES [H][C@]12CCN[C@@]1([H])CCN(C2)c1ncc(-c2ccc(C)cc2)c(n1)-c1ccc(cc1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM285038 (4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1...) Show SMILES CCCOc1ccc(cc1-c1cn(C)c(=O)c2ccc(cc12)-c1cnn(C)c1)S(=O)(=O)CC Show InChI InChI=1S/C25H27N3O4S/c1-5-11-32-24-10-8-19(33(30,31)6-2)13-22(24)23-16-27(3)25(29)20-9-7-17(12-21(20)23)18-14-26-28(4)15-18/h7-10,12-16H,5-6,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Curated by ChEMBL					Assay Description Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR method				Bioorg Med Chem Lett 28: 1811-1816 (2018) Article DOI: 10.1016/j.bmcl.2018.04.016 BindingDB Entry DOI: 10.7270/Q20Z75WN
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM191600 (2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl...) Show SMILES Cc1cc(Cl)ccc1COc1ccnn1-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C17H14ClN3O3/c1-11-8-14(18)3-2-13(11)10-24-16-5-7-20-21(16)15-9-12(17(22)23)4-6-19-15/h2-9H,10H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503507 (CHEMBL4451607 | US10626103, Example 53) Show SMILES Cc1c(nc(-c2ccc(C#N)c(F)c2)n1-c1ccc2nn(C)c(Cl)c2c1)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H23ClFN7O/c1-14-22(25(35)33-9-3-4-17(29)13-33)30-24(15-5-6-16(12-28)20(27)10-15)34(14)18-7-8-21-19(11-18)23(26)32(2)31-21/h5-8,10-11,17H,3-4,9,13,29H2,1-2H3/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM263992 (2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridin...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Br)cc1 Show InChI InChI=1S/C16H12BrN3O3/c17-13-3-1-11(2-4-13)10-23-15-6-8-19-20(15)14-9-12(16(21)22)5-7-18-14/h1-9H,10H2,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50158627 (CHEMBL3787482 | US10023592, Example 81) Show SMILES CCOc1ccc(cc1-c1cn(C)c(=O)c2ccc(cc12)-c1cnn(C)c1)S(=O)(=O)CC Show InChI InChI=1S/C24H25N3O4S/c1-5-31-23-10-8-18(32(29,30)6-2)12-21(23)22-15-26(3)24(28)19-9-7-16(11-20(19)22)17-13-25-27(4)14-17/h7-15H,5-6H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Curated by ChEMBL					Assay Description Inhibition of BRD4-BD1 in human Raji cells assessed as downregulation of MYC gene expression by PCR method				Bioorg Med Chem Lett 28: 1811-1816 (2018) Article DOI: 10.1016/j.bmcl.2018.04.016 BindingDB Entry DOI: 10.7270/Q20Z75WN
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50554231 (CHEMBL4796870) Show SMILES Cc1ccc(cc1)-c1cnc(C[C@H]2CCNC2)nc1-c1ccc(cc1)C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503503 (CHEMBL4548929 | US10626103, Example 22) Show SMILES Cc1c(nc(-c2ccc(C#N)c(F)c2)n1-c1ccc2nn(C)cc2c1)C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C24H22FN7O/c1-14-22(24(33)31-8-7-18(27)13-31)28-23(15-3-4-16(11-26)20(25)10-15)32(14)19-5-6-21-17(9-19)12-30(2)29-21/h3-6,9-10,12,18H,7-8,13,27H2,1-2H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384706 (CHEMBL2037204) Show SMILES CN1CCCN(CC1)C(=O)c1ccc(F)c(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H23ClFN3O3/c1-30-9-2-10-31(12-11-30)26(33)16-3-6-22(28)21(13-16)24-8-5-18(34-24)15-20-19-14-17(27)4-7-23(19)29-25(20)32/h3-8,13-15H,2,9-12H2,1H3,(H,29,32)/b20-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM263991 (2-{5-[(4-ethylbenzyl)oxy]- 1H-pyrazol-1-yl}pyridin...) Show SMILES CCc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)cc1 Show InChI InChI=1S/C18H17N3O3/c1-2-13-3-5-14(6-4-13)12-24-17-8-10-20-21(17)16-11-15(18(22)23)7-9-19-16/h3-11H,2,12H2,1H3,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM285038 (4-(5-ethylsulfonyl-2-propoxyphenyl)-2-methyl- 6-(1...) Show SMILES CCCOc1ccc(cc1-c1cn(C)c(=O)c2ccc(cc12)-c1cnn(C)c1)S(=O)(=O)CC Show InChI InChI=1S/C25H27N3O4S/c1-5-11-32-24-10-8-19(33(30,31)6-2)13-22(24)23-16-27(3)25(29)20-9-7-17(12-21(20)23)18-14-26-28(4)15-18/h7-10,12-16H,5-6,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Curated by ChEMBL					Assay Description Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...				Bioorg Med Chem Lett 28: 1811-1816 (2018) Article DOI: 10.1016/j.bmcl.2018.04.016 BindingDB Entry DOI: 10.7270/Q20Z75WN
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503493 (CHEMBL4448358 | US10626103, Example 23) Show SMILES Cc1c(nc(-c2ccc(C#N)c(F)c2)n1-c1ccc2n(C)ncc2c1)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C25H24FN7O/c1-15-23(25(34)32-9-3-4-19(28)14-32)30-24(16-5-6-17(12-27)21(26)11-16)33(15)20-7-8-22-18(10-20)13-29-31(22)2/h5-8,10-11,13,19H,3-4,9,14,28H2,1-2H3/t19-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM301089 (4-[2-(4-aminopiperidin-1-yl)-5-(4- methylphenyl)py...) Show SMILES Cc1ccc(cc1)-c1cnc(nc1-c1ccc(cc1)C#N)N1CCC(N)CC1 Show InChI InChI=1S/C23H23N5/c1-16-2-6-18(7-3-16)21-15-26-23(28-12-10-20(25)11-13-28)27-22(21)19-8-4-17(14-24)5-9-19/h2-9,15,20H,10-13,25H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of LSD1 (unknown origin) using H3K4me1 substrate by TR-FRET assay				Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00978 BindingDB Entry DOI: 10.7270/Q2RJ4P33
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM264025 (2-(4-[2-(dimethylamino)ethyl]- 5-[(4- fluorophenyl...) Show SMILES CN(C)CCc1cnn(c1OCc1ccc(F)cc1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C20H21FN4O3/c1-24(2)10-8-16-12-23-25(18-11-15(20(26)27)7-9-22-18)19(16)28-13-14-3-5-17(21)6-4-14/h3-7,9,11-12H,8,10,13H2,1-2H3,(H,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5A (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264001 (2-{5-[(4-chloro-2- fluorobenzyl)oxy]-1H-pyrazol-1-...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Cl)cc1F Show InChI InChI=1S/C16H11ClFN3O3/c17-12-2-1-11(13(18)8-12)9-24-15-4-6-20-21(15)14-7-10(16(22)23)3-5-19-14/h1-8H,9H2,(H,22,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264030 (2-[5-[(4-chloro-2- ethoxyphenyl)methoxy]pyrazol-1-...) Show SMILES CCOc1cc(Cl)ccc1COc1ccnn1-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C18H16ClN3O4/c1-2-25-15-10-14(19)4-3-13(15)11-26-17-6-8-21-22(17)16-9-12(18(23)24)5-7-20-16/h3-10H,2,11H2,1H3,(H,23,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM50158703 (CHEMBL3785832 | US10173996, Example 53 | US9604961...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Cl)cc1 Show InChI InChI=1S/C16H12ClN3O3/c17-13-3-1-11(2-4-13)10-23-15-6-8-19-20(15)14-9-12(16(21)22)5-7-18-14/h1-9H,10H2,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM263978 (2-{5-[(4-methoxybenzyl)oxy]-1H- pyrazol-1-yl}pyrid...) Show SMILES COc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)cc1 Show InChI InChI=1S/C17H15N3O4/c1-23-14-4-2-12(3-5-14)11-24-16-7-9-19-20(16)15-10-13(17(21)22)6-8-18-15/h2-10H,11H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM264020 (2-[5-[(4- cyanophenyl)methoxy]pyrazol-1- yl]pyridi...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(cc1)C#N Show InChI InChI=1S/C17H12N4O3/c18-10-12-1-3-13(4-2-12)11-24-16-6-8-20-21(16)15-9-14(17(22)23)5-7-19-15/h1-9H,11H2,(H,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5A (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503516 (CHEMBL4447527 | US10626103, Example 12) Show SMILES COc1ccc(cc1)-n1c(C)c(nc1-c1ccc(C#N)c(F)c1)C(=O)N1CCC[C@@H](N)C1 |r| Show InChI InChI=1S/C24H24FN5O2/c1-15-22(24(31)29-11-3-4-18(27)14-29)28-23(16-5-6-17(13-26)21(25)12-16)30(15)19-7-9-20(32-2)10-8-19/h5-10,12,18H,3-4,11,14,27H2,1-2H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503505 (CHEMBL4516248 | US10626103, Example 49) Show SMILES CN[C@H]1CCN(C1)C(=O)c1nc(-c2ccc(C#N)c(F)c2)n(c1C)-c1cc2cn(C)nc2cc1F |r,wU:2.1,(54.64,-1.99,;53.31,-2.77,;53.32,-4.31,;54.65,-5.08,;54.33,-6.59,;52.81,-6.75,;52.17,-5.35,;52.04,-8.09,;52.81,-9.42,;50.5,-8.09,;49.63,-6.81,;48.16,-7.25,;46.82,-6.48,;45.49,-7.25,;44.16,-6.49,;44.15,-4.94,;42.82,-4.18,;41.48,-3.41,;45.49,-4.16,;45.49,-2.62,;46.82,-4.93,;48.11,-8.79,;49.56,-9.31,;49.99,-10.78,;46.78,-9.56,;45.45,-8.8,;44.11,-9.57,;42.65,-9.1,;41.75,-10.35,;40.21,-10.36,;42.66,-11.59,;44.12,-11.11,;45.45,-11.88,;46.79,-11.11,;48.12,-11.88,)| Show InChI InChI=1S/C25H23F2N7O/c1-14-23(25(35)33-7-6-18(13-33)29-2)30-24(15-4-5-16(11-28)19(26)8-15)34(14)22-9-17-12-32(3)31-21(17)10-20(22)27/h4-5,8-10,12,18,29H,6-7,13H2,1-3H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503499 (CHEMBL4454128 | US10626103, Example 18) Show SMILES COc1ccc(cc1F)-n1c(C)c(nc1-c1ccc(C#N)c(F)c1)C(=O)N1CC[C@H](N)C1 |r| Show InChI InChI=1S/C23H21F2N5O2/c1-13-21(23(31)29-8-7-16(27)12-29)28-22(14-3-4-15(11-26)18(24)9-14)30(13)17-5-6-20(32-2)19(25)10-17/h3-6,9-10,16H,7-8,12,27H2,1-2H3/t16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM263990 (2-{5-[(4-methylbenzyl)oxy]-1H- pyrazol-1-yl}pyridi...) Show SMILES Cc1ccc(COc2ccnn2-c2cc(ccn2)C(O)=O)cc1 Show InChI InChI=1S/C17H15N3O3/c1-12-2-4-13(5-3-12)11-23-16-7-9-19-20(16)15-10-14(17(21)22)6-8-18-15/h2-10H,11H2,1H3,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264021 (2-[5-[(4-chloro-2- phenylmethoxyphenyl)methoxy] py...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Cl)cc1OCc1ccccc1 Show InChI InChI=1S/C23H18ClN3O4/c24-19-7-6-18(20(13-19)30-14-16-4-2-1-3-5-16)15-31-22-9-11-26-27(22)21-12-17(23(28)29)8-10-25-21/h1-13H,14-15H2,(H,28,29)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM263975 (2-{5-[(4-fluorobenzyl)oxy]-1H- pyrazol-1-yl}pyridi...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(F)cc1 Show InChI InChI=1S/C16H12FN3O3/c17-13-3-1-11(2-4-13)10-23-15-6-8-19-20(15)14-9-12(16(21)22)5-7-18-14/h1-9H,10H2,(H,21,22)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM50158627 (CHEMBL3787482 | US10023592, Example 81) Show SMILES CCOc1ccc(cc1-c1cn(C)c(=O)c2ccc(cc12)-c1cnn(C)c1)S(=O)(=O)CC Show InChI InChI=1S/C24H25N3O4S/c1-5-31-23-10-8-18(32(29,30)6-2)12-21(23)22-15-26(3)24(28)19-9-7-16(11-20(19)22)17-13-25-27(4)14-17/h7-15H,5-6H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Curated by ChEMBL					Assay Description Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...				Bioorg Med Chem Lett 28: 1811-1816 (2018) Article DOI: 10.1016/j.bmcl.2018.04.016 BindingDB Entry DOI: 10.7270/Q20Z75WN
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Homo sapiens (Human))	BDBM263974 (2-(5-(benzyloxy)-1H-pyrazol-1- yl)isonicotinic aci...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccccc1 Show InChI InChI=1S/C16H13N3O3/c20-16(21)13-6-8-17-14(10-13)19-15(7-9-18-19)22-11-12-4-2-1-3-5-12/h1-10H,11H2,(H,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM4C (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM285167 (2-methyl-6-(1-methylpyrazol-4-yl)-4-(5- methylsulf...) Show SMILES CCCOc1ccc(cc1-c1cn(C)c(=O)c2ccc(cc12)-c1cnn(C)c1)S(C)(=O)=O Show InChI InChI=1S/C24H25N3O4S/c1-5-10-31-23-9-7-18(32(4,29)30)12-21(23)22-15-26(2)24(28)19-8-6-16(11-20(19)22)17-13-25-27(3)14-17/h6-9,11-15H,5,10H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Quanticel Research Curated by ChEMBL					Assay Description Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...				Bioorg Med Chem Lett 28: 1811-1816 (2018) Article DOI: 10.1016/j.bmcl.2018.04.016 BindingDB Entry DOI: 10.7270/Q20Z75WN
					More data for this Ligand-Target Pair
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50503500 (CHEMBL4451430 | US10626103, Example 62) Show SMILES COc1ccc(cc1F)-n1c(C)c(nc1-c1ccc(C#N)c(F)c1)C(=O)N[C@@H]1CCCNC1 |r| Show InChI InChI=1S/C24H23F2N5O2/c1-14-22(24(32)29-17-4-3-9-28-13-17)30-23(15-5-6-16(12-27)19(25)10-15)31(14)18-7-8-21(33-2)20(26)11-18/h5-8,10-11,17,28H,3-4,9,13H2,1-2H3,(H,29,32)/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of LSD1 (unknown origin)				Bioorg Med Chem Lett 29: 103-106 (2019) Article DOI: 10.1016/j.bmcl.2018.11.001 BindingDB Entry DOI: 10.7270/Q2W95DFG
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-2 (Homo sapiens (Human))	BDBM50384706 (CHEMBL2037204) Show SMILES CN1CCCN(CC1)C(=O)c1ccc(F)c(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H23ClFN3O3/c1-30-9-2-10-31(12-11-30)26(33)16-3-6-22(28)21(13-16)24-8-5-18(34-24)15-20-19-14-17(27)4-7-23(19)29-25(20)32/h3-8,13-15H,2,9-12H2,1H3,(H,29,32)/b20-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim2 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384714 (CHEMBL2037200) Show SMILES CN1CCCN(CC1)C(=O)c1cccc(c1)-c1ccc(\C=C2\C(=O)Nc3ccc(Cl)cc23)o1 Show InChI InChI=1S/C26H24ClN3O3/c1-29-10-3-11-30(13-12-29)26(32)18-5-2-4-17(14-18)24-9-7-20(33-24)16-22-21-15-19(27)6-8-23(21)28-25(22)31/h2,4-9,14-16H,3,10-13H2,1H3,(H,28,31)/b22-16+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM50384715 (CHEMBL2037201) Show SMILES Clc1ccc2NC(=O)\C(=C\c3ccc(o3)-c3cccc(c3)C(=O)N3CCCNCC3)c2c1 Show InChI InChI=1S/C25H22ClN3O3/c26-18-5-7-22-20(14-18)21(24(30)28-22)15-19-6-8-23(32-19)16-3-1-4-17(13-16)25(31)29-11-2-9-27-10-12-29/h1,3-8,13-15,27H,2,9-12H2,(H,28,30)/b21-15+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of human recombinant Pim1 using RSRHSSYPAGT as substrate by radiometric assay				ACS Med Chem Lett 3: 135-139 (2012) Article DOI: 10.1021/ml200259q BindingDB Entry DOI: 10.7270/Q2X92CBW
					More data for this Ligand-Target Pair
NACHT, LRR and PYD domains-containing protein 3 (Homo sapiens (Human))	BDBM50607509 (CHEMBL5219789) Show SMILES CN[C@@H]1COc2c(cnn2C1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01250 BindingDB Entry DOI: 10.7270/Q2WD44PZ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysine-specific demethylase 5A (Homo sapiens (Human))	BDBM263992 (2-{5-[(4-bromobenzyl)oxy]-1H- pyrazol-1-yl}pyridin...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Br)cc1 Show InChI InChI=1S/C16H12BrN3O3/c17-13-3-1-11(2-4-13)10-23-15-6-8-19-20(15)14-9-12(16(21)22)5-7-18-14/h1-9H,10H2,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5A (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Homo sapiens (Human))	BDBM264022 (2-[5-[[4-chloro-2- (cyclopropylmethoxy(phenyl] met...) Show SMILES OC(=O)c1ccnc(c1)-n1nccc1OCc1ccc(Cl)cc1OCC1CC1 Show InChI InChI=1S/C20H18ClN3O4/c21-16-4-3-15(17(10-16)27-11-13-1-2-13)12-28-19-6-8-23-24(19)18-9-14(20(25)26)5-7-22-18/h3-10,13H,1-2,11-12H2,(H,25,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) preincubated with enzyme				Bioorg Med Chem Lett 28: 1490-1494 (2018) Article DOI: 10.1016/j.bmcl.2018.03.083 BindingDB Entry DOI: 10.7270/Q26Q20W4
					More data for this Ligand-Target Pair

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