Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'storustovu' and Initial = 'si'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182527 (4-(3,3-diphenyl-1-propyl)-5-(4-piperidyl)isothiazo...) Show SMILES O=c1[nH]sc(C2CCNCC2)c1CCC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H26N2OS/c26-23-21(22(27-25-23)19-13-15-24-16-14-19)12-11-20(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,19-20,24H,11-16H2,(H,25,26)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182520 (4-((1-bromo-2-naphthyl)methyl)-5-(4-piperidyl)isot...) Show SMILES Brc1c(Cc2c(s[nH]c2=O)C2CCNCC2)ccc2ccccc12 Show InChI InChI=1S/C19H19BrN2OS/c20-17-14(6-5-12-3-1-2-4-15(12)17)11-16-18(24-22-19(16)23)13-7-9-21-10-8-13/h1-6,13,21H,7-11H2,(H,22,23)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370912 (CHEMBL1202309) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C20H20N2O3/c23-20-18(19(25-22-20)15-10-12-21-13-11-15)14-6-8-17(9-7-14)24-16-4-2-1-3-5-16/h1-9,15,21H,10-13H2,(H,22,23)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370916 (CHEMBL1202310) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1csc(c1)-c1ccccc1 Show InChI InChI=1S/C18H18N2O2S/c21-18-16(17(22-20-18)13-6-8-19-9-7-13)14-10-15(23-11-14)12-4-2-1-3-5-12/h1-5,10-11,13,19H,6-9H2,(H,20,21)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50208721 (4-(biphenyl-3-yl)-5-(piperidin-4-yl)isoxazol-3-ol ...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1cccc(c1)-c1ccccc1 Show InChI InChI=1S/C20H20N2O2/c23-20-18(19(24-22-20)15-9-11-21-12-10-15)17-8-4-7-16(13-17)14-5-2-1-3-6-14/h1-8,13,15,21H,9-12H2,(H,22,23)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50113806 (4-(3,3-Diphenyl-propyl)-5-piperidin-4-yl-isoxazol-...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1CCC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C23H26N2O2/c26-23-21(22(27-25-23)19-13-15-24-16-14-19)12-11-20(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-10,19-20,24H,11-16H2,(H,25,26)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182524 (4-(2-naphthylmethyl)-5-(4-piperidyl)isothiazol-3-o...) Show SMILES O=c1[nH]sc(C2CCNCC2)c1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C19H20N2OS/c22-19-17(18(23-21-19)15-7-9-20-10-8-15)12-13-5-6-14-3-1-2-4-16(14)11-13/h1-6,11,15,20H,7-10,12H2,(H,21,22)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50208717 (4-(bromo(naphthalen-2-yl)methyl)-5-(piperidin-4-yl...) Show SMILES BrC(c1c(o[nH]c1=O)C1CCNCC1)c1ccc2ccccc2c1 Show InChI InChI=1S/C19H19BrN2O2/c20-17(15-6-5-12-3-1-2-4-14(12)11-15)16-18(24-22-19(16)23)13-7-9-21-10-8-13/h1-6,11,13,17,21H,7-10H2,(H,22,23)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370917 (CHEMBL1202300) Show SMILES Clc1cccc(c1)-c1c(o[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C14H15ClN2O2/c15-11-3-1-2-10(8-11)12-13(19-17-14(12)18)9-4-6-16-7-5-9/h1-3,8-9,16H,4-7H2,(H,17,18)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370918 (CHEMBL1202304) Show SMILES Nc1cccc(c1)-c1c(o[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C14H17N3O2/c15-11-3-1-2-10(8-11)12-13(19-17-14(12)18)9-4-6-16-7-5-9/h1-3,8-9,16H,4-7,15H2,(H,17,18)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370915 (CHEMBL1202302) Show SMILES Clc1cc(Cl)cc(c1)-c1c(o[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C14H14Cl2N2O2/c15-10-5-9(6-11(16)7-10)12-13(20-18-14(12)19)8-1-3-17-4-2-8/h5-8,17H,1-4H2,(H,18,19)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370911 (CHEMBL1202308) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H20N2O2/c23-20-18(19(24-22-20)17-10-12-21-13-11-17)16-8-6-15(7-9-16)14-4-2-1-3-5-14/h1-9,17,21H,10-13H2,(H,22,23)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370913 (CHEMBL1202306) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1ccsc1 Show InChI InChI=1S/C12H14N2O2S/c15-12-10(9-3-6-17-7-9)11(16-14-12)8-1-4-13-5-2-8/h3,6-8,13H,1-2,4-5H2,(H,14,15)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370914 (CHEMBL1202299) Show SMILES Clc1ccccc1-c1c(o[nH]c1=O)C1CCNCC1 |(2.11,1.42,;3.31,1.71,;3.74,3.19,;5.24,3.56,;6.3,2.44,;5.87,.96,;4.37,.6,;4.06,-.9,;2.67,-1.54,;2.81,-3.06,;4.31,-3.38,;5.09,-2.05,;6.31,-1.92,;1.33,-.77,;1.33,.77,;,1.54,;-1.33,.77,;-1.33,-.77,;,-1.54,)| Show InChI InChI=1S/C14H15ClN2O2/c15-11-4-2-1-3-10(11)12-13(19-17-14(12)18)9-5-7-16-8-6-9/h1-4,9,16H,5-8H2,(H,17,18)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370921 (CHEMBL1202303) Show SMILES [O-][N+](=O)c1cccc(c1)-c1c(o[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C14H15N3O4/c18-14-12(10-2-1-3-11(8-10)17(19)20)13(21-16-14)9-4-6-15-7-5-9/h1-3,8-9,15H,4-7H2,(H,16,18)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50159237 (4-(naphthalen-2-yl)-5-(piperidin-4-yl)isoxazol-3-o...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1ccc2ccccc2c1 Show InChI InChI=1S/C18H18N2O2/c21-18-16(17(22-20-18)13-7-9-19-10-8-13)15-6-5-12-3-1-2-4-14(12)11-15/h1-6,11,13,19H,7-10H2,(H,20,21)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50159235 (4-Phenyl-5-piperidin-4-yl-isoxazol-3-ol | 4-phenyl...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1ccccc1 Show InChI InChI=1S/C14H16N2O2/c17-14-12(10-4-2-1-3-5-10)13(18-16-14)11-6-8-15-9-7-11/h1-5,11,15H,6-9H2,(H,16,17)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	159	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50159239 (4-((1-phenylnaphthalen-2-yl)methyl)-5-(piperidin-4...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1Cc1ccc2ccccc2c1-c1ccccc1 Show InChI InChI=1S/C25H24N2O2/c28-25-22(24(29-27-25)19-12-14-26-15-13-19)16-20-11-10-17-6-4-5-9-21(17)23(20)18-7-2-1-3-8-18/h1-11,19,26H,12-16H2,(H,27,28)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370910 (CHEMBL1202301) Show SMILES Clc1ccc(cc1)-c1c(o[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C14H15ClN2O2/c15-11-3-1-9(2-4-11)12-13(19-17-14(12)18)10-5-7-16-8-6-10/h1-4,10,16H,5-8H2,(H,17,18)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182521 (5-(4-piperidyl)-4-propylisothiazol-3-ol | CHEMBL38...) Show SMILES CCCc1c(s[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C11H18N2OS/c1-2-3-9-10(15-13-11(9)14)8-4-6-12-7-5-8/h8,12H,2-7H2,1H3,(H,13,14)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50001572 ((gabazine)4-[6-Imino-3-(4-methoxy-phenyl)-6H-pyrid...) Show SMILES COc1ccc(cc1)-c1ccc(=N)n(CCCC(O)=O)n1 Show InChI InChI=1S/C15H17N3O3/c1-21-12-6-4-11(5-7-12)13-8-9-14(16)18(17-13)10-2-3-15(19)20/h4-9,16H,2-3,10H2,1H3,(H,19,20)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370919 (CHEMBL1202307) Show SMILES CC(C)(C)c1ccc(cc1)-c1c(o[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C18H24N2O2/c1-18(2,3)14-6-4-12(5-7-14)15-16(22-20-17(15)21)13-8-10-19-11-9-13/h4-7,13,19H,8-11H2,1-3H3,(H,20,21)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	257	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50159229 (4-(naphthalen-1-yl)-5-(piperidin-4-yl)isoxazol-3-o...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1cccc2ccccc12 |(3.22,1.3,;2.59,-.12,;3.35,-1.45,;2.31,-2.59,;.89,-1.96,;-.43,-2.72,;-1.76,-1.96,;-3.1,-2.72,;-3.1,-4.28,;-1.76,-5.03,;-.43,-4.28,;1.08,-.43,;-.06,.61,;-1.53,.14,;-2.67,1.18,;-2.34,2.7,;-.88,3.17,;-.53,4.66,;.92,5.12,;2.08,4.09,;1.73,2.58,;.26,2.12,)| Show InChI InChI=1S/C18H18N2O2/c21-18-16(17(22-20-18)13-8-10-19-11-9-13)15-7-3-5-12-4-1-2-6-14(12)15/h1-7,13,19H,8-11H2,(H,20,21)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	334	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50095533 (4-(naphthalen-2-ylmethyl)-5-(piperidin-4-yl)isoxaz...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C19H20N2O2/c22-19-17(18(23-21-19)15-7-9-20-10-8-15)12-13-5-6-14-3-1-2-4-16(14)11-13/h1-6,11,15,20H,7-10,12H2,(H,21,22)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50095533 (4-(naphthalen-2-ylmethyl)-5-(piperidin-4-yl)isoxaz...) Show SMILES O=c1[nH]oc(C2CCNCC2)c1Cc1ccc2ccccc2c1 Show InChI InChI=1S/C19H20N2O2/c22-19-17(18(23-21-19)15-7-9-20-10-8-15)12-13-5-6-14-3-1-2-4-16(14)11-13/h1-6,11,15,20H,7-10,12H2,(H,21,22)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50370909 (CHEMBL1202305) Show SMILES O=c1[nH]oc(C2CCNCC2)c1-c1cccnc1 Show InChI InChI=1S/C13H15N3O2/c17-13-11(10-2-1-5-15-8-10)12(18-16-13)9-3-6-14-7-4-9/h1-2,5,8-9,14H,3-4,6-7H2,(H,16,17)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	427	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182526 (4-benzyl-5-(4-piperidyl)isothiazol-3-ol | CHEMBL20...) Show SMILES O=c1[nH]sc(C2CCNCC2)c1Cc1ccccc1 Show InChI InChI=1S/C15H18N2OS/c18-15-13(10-11-4-2-1-3-5-11)14(19-17-15)12-6-8-16-9-7-12/h1-5,12,16H,6-10H2,(H,17,18)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	465	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182525 (4-(2,2-diphenyl-1-ethyl)-5-(4-piperidyl)isothiazol...) Show SMILES O=c1[nH]sc(C2CCNCC2)c1CC(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H24N2OS/c25-22-20(21(26-24-22)18-11-13-23-14-12-18)15-19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-10,18-19,23H,11-15H2,(H,24,25)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50182522 (4-Methyl-5-(4-piperidyl)isothiazol-3-ol | CHEMBL20...) Show SMILES Cc1c(s[nH]c1=O)C1CCNCC1 Show InChI InChI=1S/C9H14N2OS/c1-6-8(13-11-9(6)12)7-2-4-10-5-3-7/h7,10H,2-5H2,1H3,(H,11,12)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.88E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50032954 (5-(piperidin-4-yl)isoxazol-3-ol | 5-Piperidin-4-yl...) Show SMILES O=c1cc(o[nH]1)C1CCNCC1 Show InChI InChI=1S/C8H12N2O2/c11-8-5-7(12-10-8)6-1-3-9-4-2-6/h5-6,9H,1-4H2,(H,10,11)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Copenhagen Curated by ChEMBL					Assay Description Antagonist activity at human GABAA alpha-1-beta-3-gamma-2S expressed in Xenopus oocytes by two-electrode voltage-clamp electrophysiology				J Med Chem 50: 1988-92 (2007) Article DOI: 10.1021/jm070038n BindingDB Entry DOI: 10.7270/Q2D21ZDC
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50032951 (5-(piperidin-4-yl)isothiazol-3-ol | 5-Piperidin-4-...) Show SMILES O=c1cc(s[nH]1)C1CCNCC1 Show InChI InChI=1S/C8H12N2OS/c11-8-5-7(12-10-8)6-1-3-9-4-2-6/h5-6,9H,1-4H2,(H,10,11)	UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.57E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Danish University of Pharmaceutical Sciences Curated by ChEMBL					Assay Description Binding affinity at human GABAA alpha1beta3gamma2S expressed in Xenopus oocytes by voltage-clamp electrophysiology				J Med Chem 49: 1388-96 (2006) Article DOI: 10.1021/jm050987l BindingDB Entry DOI: 10.7270/Q2VD6Z1T
					More data for this Ligand-Target Pair