Found 50 hits with Last Name = 'sturis' and Initial = 'j' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109540
(3-{4-[3-(5,7-Dioxa-12-aza-dibenzo[a,d]cycloocten-1...)Show SMILES CCOC(Cc1ccc(OCCCN2c3ccccc3OCOc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C27H29NO6/c1-2-31-26(27(29)30)18-20-12-14-21(15-13-20)32-17-7-16-28-22-8-3-5-10-24(22)33-19-34-25-11-6-4-9-23(25)28/h3-6,8-15,26H,2,7,16-19H2,1H3,(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087746
(CHEMBL428139 | GLP-1(7-37) | Glucagon like peptide...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O Show InChI InChI=1S/C151H228N40O47/c1-17-77(10)121(148(236)169-81(14)127(215)177-105(60-87-63-160-92-36-25-24-35-90(87)92)138(226)179-101(56-74(4)5)139(227)188-119(75(6)7)146(234)176-94(37-26-28-52-152)130(218)161-65-111(199)170-93(39-30-54-159-151(156)157)129(217)164-68-118(210)211)190-140(228)103(57-84-31-20-18-21-32-84)180-135(223)99(47-51-116(206)207)175-134(222)95(38-27-29-53-153)172-125(213)79(12)166-124(212)78(11)168-133(221)98(44-48-110(155)198)171-112(200)66-162-132(220)97(46-50-115(204)205)174-136(224)100(55-73(2)3)178-137(225)102(59-86-40-42-89(197)43-41-86)181-143(231)107(69-192)184-145(233)109(71-194)185-147(235)120(76(8)9)189-142(230)106(62-117(208)209)182-144(232)108(70-193)186-150(238)123(83(16)196)191-141(229)104(58-85-33-22-19-23-34-85)183-149(237)122(82(15)195)187-113(201)67-163-131(219)96(45-49-114(202)203)173-126(214)80(13)167-128(216)91(154)61-88-64-158-72-165-88/h18-25,31-36,40-43,63-64,72-83,91,93-109,119-123,160,192-197H,17,26-30,37-39,44-62,65-71,152-154H2,1-16H3,(H2,155,198)(H,158,165)(H,161,218)(H,162,220)(H,163,219)(H,164,217)(H,166,212)(H,167,216)(H,168,221)(H,169,236)(H,170,199)(H,171,200)(H,172,213)(H,173,214)(H,174,224)(H,175,222)(H,176,234)(H,177,215)(H,178,225)(H,179,226)(H,180,223)(H,181,231)(H,182,232)(H,183,237)(H,184,233)(H,185,235)(H,186,238)(H,187,201)(H,188,227)(H,189,230)(H,190,228)(H,191,229)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H4,156,157,159)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | n/a |
Novo Nordisk Als
Curated by ChEMBL
| Assay Description
Binding affinity to human GLP1 receptor expressed in BHK cells |
Proc Natl Acad Sci USA 104: 937-42 (2007)
Article DOI: 10.1073/pnas.0605701104
BindingDB Entry DOI: 10.7270/Q21R6RD8 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109542
(2-Ethoxy-3-{4-[2-(9H-fluoren-9-yl)-ethoxy]-phenyl}...)Show SMILES CCOC(Cc1ccc(OCCC2c3ccccc3-c3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C26H26O4/c1-2-29-25(26(27)28)17-18-11-13-19(14-12-18)30-16-15-24-22-9-5-3-7-20(22)21-8-4-6-10-23(21)24/h3-14,24-25H,2,15-17H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109544
(3-[4-(2-beta-Carbolin-9-yl-ethoxy)-phenyl]-2-ethox...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccccc3c3ccncc23)cc1)C(O)=O Show InChI InChI=1S/C24H24N2O4/c1-2-29-23(24(27)28)15-17-7-9-18(10-8-17)30-14-13-26-21-6-4-3-5-19(21)20-11-12-25-16-22(20)26/h3-12,16,23H,2,13-15H2,1H3,(H,27,28)/t23-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 11 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109543
(3-{4-[2-(10,11-Dihydro-dibenzo[b,f]azepin-5-yl)-et...)Show SMILES CCOC(Cc1ccc(OCCN2c3ccccc3CCc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C27H29NO4/c1-2-31-26(27(29)30)19-20-11-15-23(16-12-20)32-18-17-28-24-9-5-3-7-21(24)13-14-22-8-4-6-10-25(22)28/h3-12,15-16,26H,2,13-14,17-19H2,1H3,(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 750 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109545
(3-[4-(2-beta-Carbolin-9-yl-ethoxy)-phenyl]-2-ethox...)Show SMILES CCOC(Cc1ccc(OCCn2c3ccccc3c3ccncc23)cc1)C(O)=O Show InChI InChI=1S/C24H24N2O4/c1-2-29-23(24(27)28)15-17-7-9-18(10-8-17)30-14-13-26-21-6-4-3-5-19(21)20-11-12-25-16-22(20)26/h3-12,16,23H,2,13-15H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 670 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50109546
(5-[(3aS,4R,5R,6aS)-5-Hydroxy-4-((S)-3-hydroxy-oct-...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2C\C(C[C@H]12)=C\CCCC(O)=O Show InChI InChI=1S/C21H34O4/c1-2-3-4-8-17(22)10-11-18-19-13-15(7-5-6-9-21(24)25)12-16(19)14-20(18)23/h7,10-11,16-20,22-23H,2-6,8-9,12-14H2,1H3,(H,24,25)/b11-10+,15-7-/t16-,17-,18+,19-,20+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.41E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transcriptional activation of hPPAR delta |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109547
((S)-3-(4-(2-CARBAZOL-9-YL-ETHOXY)-PHENYL)-2-ETHOXY...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccccc3c3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C25H25NO4/c1-2-29-24(25(27)28)17-18-11-13-19(14-12-18)30-16-15-26-22-9-5-3-7-20(22)21-8-4-6-10-23(21)26/h3-14,24H,2,15-17H2,1H3,(H,27,28)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 360 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109548
(3-{4-[2-(3-Bromo-carbazol-9-yl)-ethoxy]-phenyl}-2-...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccccc3c3cc(Br)ccc23)cc1)C(O)=O Show InChI InChI=1S/C25H24BrNO4/c1-2-30-24(25(28)29)15-17-7-10-19(11-8-17)31-14-13-27-22-6-4-3-5-20(22)21-16-18(26)9-12-23(21)27/h3-12,16,24H,2,13-15H2,1H3,(H,28,29)/t24-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 330 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109549
(2-Ethoxy-3-{4-[2-(9H-xanthen-9-yl)-ethoxy]-phenyl}...)Show SMILES CCOC(Cc1ccc(OCCC2c3ccccc3Oc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C26H26O5/c1-2-29-25(26(27)28)17-18-11-13-19(14-12-18)30-16-15-20-21-7-3-5-9-23(21)31-24-10-6-4-8-22(20)24/h3-14,20,25H,2,15-17H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109550
(3-[4-(2-Dibenzo[b,f]azepin-5-yl-ethoxy)-phenyl]-2-...)Show SMILES CCOC(Cc1ccc(OCCN2c3ccccc3C=Cc3ccccc23)cc1)C(O)=O |c:20| Show InChI InChI=1S/C27H27NO4/c1-2-31-26(27(29)30)19-20-11-15-23(16-12-20)32-18-17-28-24-9-5-3-7-21(24)13-14-22-8-4-6-10-25(22)28/h3-16,26H,2,17-19H2,1H3,(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109552
(2-Ethoxy-3-[4-(2-fluoren-9-ylidene-ethoxy)-phenyl]...)Show SMILES [#6]-[#6]-[#8]-[#6](-[#6]-c1ccc(-[#8]-[#6]\[#6]=[#6]-2/c3ccccc3-c3ccccc-23)cc1)-[#6](-[#8])=O Show InChI InChI=1S/C26H24O4/c1-2-29-25(26(27)28)17-18-11-13-19(14-12-18)30-16-15-24-22-9-5-3-7-20(22)21-8-4-6-10-23(21)24/h3-15,25H,2,16-17H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.21E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109551
((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)Show SMILES CCO[C@@H](Cc1ccc(OCCN2c3ccccc3Oc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C25H25NO5/c1-2-29-24(25(27)28)17-18-11-13-19(14-12-18)30-16-15-26-20-7-3-5-9-22(20)31-23-10-6-4-8-21(23)26/h3-14,24H,2,15-17H2,1H3,(H,27,28)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 3.21E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109553
(3-{4-[2-(5,7-Dioxa-dibenzo[a,d]cycloocten-12-ylide...)Show SMILES [#6]-[#6]-[#8]-[#6](-[#6]-c1ccc(-[#8]-[#6]\[#6]=[#6]-2\c3ccccc3-[#8]-[#6]-[#8]-c3ccccc-23)cc1)-[#6](-[#8])=O Show InChI InChI=1S/C27H26O6/c1-2-30-26(27(28)29)17-19-11-13-20(14-12-19)31-16-15-21-22-7-3-5-9-24(22)32-18-33-25-10-6-4-8-23(21)25/h3-15,26H,2,16-18H2,1H3,(H,28,29) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 3.40E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109547
((S)-3-(4-(2-CARBAZOL-9-YL-ETHOXY)-PHENYL)-2-ETHOXY...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccccc3c3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C25H25NO4/c1-2-29-24(25(27)28)17-18-11-13-19(14-12-18)30-16-15-26-22-9-5-3-7-20(22)21-8-4-6-10-23(21)26/h3-14,24H,2,15-17H2,1H3,(H,27,28)/t24-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
UniChem
Similars
| MMDB
PDB
PubMed
| n/a | n/a | n/a | n/a | 170 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | 
3D Structure (crystal) |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109554
(3-{4-[2-(3,6-Dibromo-carbazol-9-yl)-ethoxy]-phenyl...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccc(Br)cc3c3cc(Br)ccc23)cc1)C(O)=O Show InChI InChI=1S/C25H23Br2NO4/c1-2-31-24(25(29)30)13-16-3-7-19(8-4-16)32-12-11-28-22-9-5-17(26)14-20(22)21-15-18(27)6-10-23(21)28/h3-10,14-15,24H,2,11-13H2,1H3,(H,29,30)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 220 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM28701
(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)Show SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
| PDB
PubMed
| n/a | n/a | n/a | n/a | 1.02E+5 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transcriptional activation of hPPAR delta |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109544
(3-[4-(2-beta-Carbolin-9-yl-ethoxy)-phenyl]-2-ethox...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccccc3c3ccncc23)cc1)C(O)=O Show InChI InChI=1S/C24H24N2O4/c1-2-29-23(24(27)28)15-17-7-9-18(10-8-17)30-14-13-26-21-6-4-3-5-19(21)20-11-12-25-16-22(20)26/h3-12,16,23H,2,13-15H2,1H3,(H,27,28)/t23-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 140 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM28701
(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)Show SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
| DrugBank
PDB
PubMed
| n/a | n/a | n/a | n/a | 7.35E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM28681
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| n/a | n/a | n/a | n/a | 160 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109556
(3-{4-[3-(10,11-Dihydro-dibenzo[b,f]azepin-5-yl)-pr...)Show SMILES CCOC(Cc1ccc(OCCCN2c3ccccc3CCc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C28H31NO4/c1-2-32-27(28(30)31)20-21-12-16-24(17-13-21)33-19-7-18-29-25-10-5-3-8-22(25)14-15-23-9-4-6-11-26(23)29/h3-6,8-13,16-17,27H,2,7,14-15,18-20H2,1H3,(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 760 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109555
(3-{4-[3-(6H-Dibenzo[b,e]oxepin-11-ylidene)-propoxy...)Show SMILES CCOC(Cc1ccc(OCC\C=C2\c3ccccc3COc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C28H28O5/c1-2-31-27(28(29)30)18-20-13-15-22(16-14-20)32-17-7-11-24-23-9-4-3-8-21(23)19-33-26-12-6-5-10-25(24)26/h3-6,8-16,27H,2,7,17-19H2,1H3,(H,29,30)/b24-11- | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM28681
(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)Show InChI InChI=1S/C18H19N3O3S/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15/h2-9,22H,10-12H2,1H3,(H,20,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 4.10E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109554
(3-{4-[2-(3,6-Dibromo-carbazol-9-yl)-ethoxy]-phenyl...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccc(Br)cc3c3cc(Br)ccc23)cc1)C(O)=O Show InChI InChI=1S/C25H23Br2NO4/c1-2-31-24(25(29)30)13-16-3-7-19(8-4-16)32-12-11-28-22-9-5-17(26)14-20(22)21-15-18(27)6-10-23(21)28/h3-10,14-15,24H,2,11-13H2,1H3,(H,29,30)/t24-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 44 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109549
(2-Ethoxy-3-{4-[2-(9H-xanthen-9-yl)-ethoxy]-phenyl}...)Show SMILES CCOC(Cc1ccc(OCCC2c3ccccc3Oc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C26H26O5/c1-2-29-25(26(27)28)17-18-11-13-19(14-12-18)30-16-15-20-21-7-3-5-9-23(21)31-24-10-6-4-8-22(20)24/h3-14,20,25H,2,15-17H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 9.60E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM28701
(2-(4-{2-[(4-chlorophenyl)formamido]ethyl}phenoxy)-...)Show SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O Show InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
| PDB
PubMed
| n/a | n/a | n/a | n/a | 3.57E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50085045
(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)Show SMILES Cc1c(C)c2OC(C)(COc3ccc(Cc4sc(=O)[nH]c4O)cc3)CCc2c(C)c1O Show InChI InChI=1S/C24H27NO5S/c1-13-14(2)21-18(15(3)20(13)26)9-10-24(4,30-21)12-29-17-7-5-16(6-8-17)11-19-22(27)25-23(28)31-19/h5-8,26-27H,9-12H2,1-4H3,(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 980 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109541
(2-Ethoxy-3-{4-[2-(11H-5-oxa-10-thia-dibenzo[a,d]cy...)Show SMILES CCOC(Cc1ccc(OCCC2Sc3ccccc3Oc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C26H26O5S/c1-2-29-23(26(27)28)17-18-11-13-19(14-12-18)30-16-15-24-20-7-3-4-8-21(20)31-22-9-5-6-10-25(22)32-24/h3-14,23-24H,2,15-17H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109545
(3-[4-(2-beta-Carbolin-9-yl-ethoxy)-phenyl]-2-ethox...)Show SMILES CCOC(Cc1ccc(OCCn2c3ccccc3c3ccncc23)cc1)C(O)=O Show InChI InChI=1S/C24H24N2O4/c1-2-29-23(24(27)28)15-17-7-9-18(10-8-17)30-14-13-26-21-6-4-3-5-19(21)20-11-12-25-16-22(20)26/h3-12,16,23H,2,13-15H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 91 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50049240
((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)Show InChI InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,22H,2,9-11H2,1H3,(H,21,23) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 6.68E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109557
(3-{4-[2-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-y...)Show SMILES [#6]-[#6]-[#8]-[#6](-[#6]-c1ccc(-[#8]-[#6]\[#6]=[#6]-2/c3ccccc3-[#6]-[#6]-c3ccccc-23)cc1)-[#6](-[#8])=O Show InChI InChI=1S/C28H28O4/c1-2-31-27(28(29)30)19-20-11-15-23(16-12-20)32-18-17-26-24-9-5-3-7-21(24)13-14-22-8-4-6-10-25(22)26/h3-12,15-17,27H,2,13-14,18-19H2,1H3,(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109551
((2S)-2-ETHOXY-3-{4-[2-(10H-PHENOXAZIN-10-YL)ETHOXY...)Show SMILES CCO[C@@H](Cc1ccc(OCCN2c3ccccc3Oc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C25H25NO5/c1-2-29-24(25(27)28)17-18-11-13-19(14-12-18)30-16-15-26-20-7-3-5-9-22(20)31-23-10-6-4-8-21(23)26/h3-14,24H,2,15-17H2,1H3,(H,27,28)/t24-/m0/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
DrugBank
MCE
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| MMDB
PDB
PubMed
| n/a | n/a | n/a | n/a | 570 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM24566
(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| n/a | n/a | n/a | n/a | 2.93E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50049240
((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...)Show InChI InChI=1S/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,22H,2,9-11H2,1H3,(H,21,23) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 970 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109546
(5-[(3aS,4R,5R,6aS)-5-Hydroxy-4-((S)-3-hydroxy-oct-...)Show SMILES CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)C[C@@H]2C\C(C[C@H]12)=C\CCCC(O)=O Show InChI InChI=1S/C21H34O4/c1-2-3-4-8-17(22)10-11-18-19-13-15(7-5-6-9-21(24)25)12-16(19)14-20(18)23/h7,10-11,16-20,22-23H,2-6,8-9,12-14H2,1H3,(H,24,25)/b11-10+,15-7-/t16-,17-,18+,19-,20+/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 340 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109558
(3-(4-{2-[(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten...)Show SMILES CCOC(Cc1ccc(OCCN(C)C2c3ccccc3CCc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C29H33NO4/c1-3-33-27(29(31)32)20-21-12-16-24(17-13-21)34-19-18-30(2)28-25-10-6-4-8-22(25)14-15-23-9-5-7-11-26(23)28/h4-13,16-17,27-28H,3,14-15,18-20H2,1-2H3,(H,31,32) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109555
(3-{4-[3-(6H-Dibenzo[b,e]oxepin-11-ylidene)-propoxy...)Show SMILES CCOC(Cc1ccc(OCC\C=C2\c3ccccc3COc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C28H28O5/c1-2-31-27(28(29)30)18-20-13-15-22(16-14-20)32-17-7-11-24-23-9-4-3-8-21(23)19-33-26-12-6-5-10-25(24)26/h3-6,8-16,27H,2,7,17-19H2,1H3,(H,29,30)/b24-11- | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.24E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109559
(3-{4-[2-(Dibenzo[b,f][1,4]thiazepin-11-ylamino)-et...)Show SMILES CCOC(Cc1ccc(OCCNC2=Nc3ccccc3Sc3ccccc23)cc1)C(O)=O |t:13| Show InChI InChI=1S/C26H26N2O4S/c1-2-31-22(26(29)30)17-18-11-13-19(14-12-18)32-16-15-27-25-20-7-3-5-9-23(20)33-24-10-6-4-8-21(24)28-25/h3-14,22H,2,15-17H2,1H3,(H,27,28)(H,29,30) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 9.80E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109550
(3-[4-(2-Dibenzo[b,f]azepin-5-yl-ethoxy)-phenyl]-2-...)Show SMILES CCOC(Cc1ccc(OCCN2c3ccccc3C=Cc3ccccc23)cc1)C(O)=O |c:20| Show InChI InChI=1S/C27H27NO4/c1-2-31-26(27(29)30)19-20-11-15-23(16-12-20)32-18-17-28-24-9-5-3-7-21(24)13-14-22-8-4-6-10-25(22)28/h3-16,26H,2,17-19H2,1H3,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109559
(3-{4-[2-(Dibenzo[b,f][1,4]thiazepin-11-ylamino)-et...)Show SMILES CCOC(Cc1ccc(OCCNC2=Nc3ccccc3Sc3ccccc23)cc1)C(O)=O |t:13| Show InChI InChI=1S/C26H26N2O4S/c1-2-31-22(26(29)30)17-18-11-13-19(14-12-18)32-16-15-27-25-20-7-3-5-9-23(20)33-24-10-6-4-8-21(24)28-25/h3-14,22H,2,15-17H2,1H3,(H,27,28)(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 7.50E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM24566
(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)Show InChI InChI=1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
KEGG
MMDB
PC cid
PC sid
PDB
UniChem
Patents
Similars
| PDB
PubMed
| n/a | n/a | n/a | n/a | 1.26E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair |
3D Structure (crystal) |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109552
(2-Ethoxy-3-[4-(2-fluoren-9-ylidene-ethoxy)-phenyl]...)Show SMILES [#6]-[#6]-[#8]-[#6](-[#6]-c1ccc(-[#8]-[#6]\[#6]=[#6]-2/c3ccccc3-c3ccccc-23)cc1)-[#6](-[#8])=O Show InChI InChI=1S/C26H24O4/c1-2-29-25(26(27)28)17-18-11-13-19(14-12-18)30-16-15-24-22-9-5-3-7-20(22)21-8-4-6-10-23(21)24/h3-15,25H,2,16-17H2,1H3,(H,27,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109560
(3-{4-[3-(10,11-Dihydro-dibenzo[a,d]cyclohepten-5-y...)Show SMILES [#6]-[#6]-[#8]-[#6](-[#6]-c1ccc(-[#8]-[#6]-[#6]\[#6]=[#6]-2/c3ccccc3-[#6]-[#6]-c3ccccc-23)cc1)-[#6](-[#8])=O Show InChI InChI=1S/C29H30O4/c1-2-32-28(29(30)31)20-21-13-17-24(18-14-21)33-19-7-12-27-25-10-5-3-8-22(25)15-16-23-9-4-6-11-26(23)27/h3-6,8-14,17-18,28H,2,7,15-16,19-20H2,1H3,(H,30,31) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.67E+4 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109542
(2-Ethoxy-3-{4-[2-(9H-fluoren-9-yl)-ethoxy]-phenyl}...)Show SMILES CCOC(Cc1ccc(OCCC2c3ccccc3-c3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C26H26O4/c1-2-29-25(26(27)28)17-18-11-13-19(14-12-18)30-16-15-24-22-9-5-3-7-20(22)21-8-4-6-10-23(21)24/h3-14,24-25H,2,15-17H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 490 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109540
(3-{4-[3-(5,7-Dioxa-12-aza-dibenzo[a,d]cycloocten-1...)Show SMILES CCOC(Cc1ccc(OCCCN2c3ccccc3OCOc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C27H29NO6/c1-2-31-26(27(29)30)18-20-12-14-21(15-13-20)32-17-7-16-28-22-8-3-5-10-24(22)33-19-34-25-11-6-4-9-23(25)28/h3-6,8-15,26H,2,7,16-19H2,1H3,(H,29,30) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50109548
(3-{4-[2-(3-Bromo-carbazol-9-yl)-ethoxy]-phenyl}-2-...)Show SMILES CCO[C@@H](Cc1ccc(OCCn2c3ccccc3c3cc(Br)ccc23)cc1)C(O)=O Show InChI InChI=1S/C25H24BrNO4/c1-2-30-24(25(28)29)15-17-7-10-19(11-8-17)31-14-13-27-22-6-4-3-5-20(22)21-16-18(26)9-12-23(21)27/h3-12,16,24H,2,13-15H2,1H3,(H,28,29)/t24-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 2.40E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR alpha |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50376464
(CHEMBL261639)Show InChI InChI=1S/C13H6Cl2F3N3S2/c1-5-4-19-12(22-5)23-11-10(13(16,17)18)20-8-2-6(14)7(15)3-9(8)21-11/h2-4H,1H3 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk Als
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1 receptor expressed in BHK cells assessed as cAMP accumulation |
Proc Natl Acad Sci USA 104: 937-42 (2007)
Article DOI: 10.1073/pnas.0605701104
BindingDB Entry DOI: 10.7270/Q21R6RD8 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50202222
(CHEMBL398714 | N-tert-butyl-6,7-dichloro-3-(methyl...)Show InChI InChI=1S/C13H15Cl2N3O2S/c1-13(2,3)18-11-12(21(4,19)20)17-10-6-8(15)7(14)5-9(10)16-11/h5-6H,1-4H3,(H,16,18) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
MCE
PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 101 | n/a | n/a | n/a | n/a |
Novo Nordisk Als
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1 receptor expressed in BHK cells assessed as cAMP accumulation |
Proc Natl Acad Sci USA 104: 937-42 (2007)
Article DOI: 10.1073/pnas.0605701104
BindingDB Entry DOI: 10.7270/Q21R6RD8 |
More data for this
Ligand-Target Pair | |
Glucagon-like peptide 1 receptor
(Homo sapiens (Human)) | BDBM50087746
(CHEMBL428139 | GLP-1(7-37) | Glucagon like peptide...)Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1cnc[nH]1)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(O)=O Show InChI InChI=1S/C151H228N40O47/c1-17-77(10)121(148(236)169-81(14)127(215)177-105(60-87-63-160-92-36-25-24-35-90(87)92)138(226)179-101(56-74(4)5)139(227)188-119(75(6)7)146(234)176-94(37-26-28-52-152)130(218)161-65-111(199)170-93(39-30-54-159-151(156)157)129(217)164-68-118(210)211)190-140(228)103(57-84-31-20-18-21-32-84)180-135(223)99(47-51-116(206)207)175-134(222)95(38-27-29-53-153)172-125(213)79(12)166-124(212)78(11)168-133(221)98(44-48-110(155)198)171-112(200)66-162-132(220)97(46-50-115(204)205)174-136(224)100(55-73(2)3)178-137(225)102(59-86-40-42-89(197)43-41-86)181-143(231)107(69-192)184-145(233)109(71-194)185-147(235)120(76(8)9)189-142(230)106(62-117(208)209)182-144(232)108(70-193)186-150(238)123(83(16)196)191-141(229)104(58-85-33-22-19-23-34-85)183-149(237)122(82(15)195)187-113(201)67-163-131(219)96(45-49-114(202)203)173-126(214)80(13)167-128(216)91(154)61-88-64-158-72-165-88/h18-25,31-36,40-43,63-64,72-83,91,93-109,119-123,160,192-197H,17,26-30,37-39,44-62,65-71,152-154H2,1-16H3,(H2,155,198)(H,158,165)(H,161,218)(H,162,220)(H,163,219)(H,164,217)(H,166,212)(H,167,216)(H,168,221)(H,169,236)(H,170,199)(H,171,200)(H,172,213)(H,173,214)(H,174,224)(H,175,222)(H,176,234)(H,177,215)(H,178,225)(H,179,226)(H,180,223)(H,181,231)(H,182,232)(H,183,237)(H,184,233)(H,185,235)(H,186,238)(H,187,201)(H,188,227)(H,189,230)(H,190,228)(H,191,229)(H,202,203)(H,204,205)(H,206,207)(H,208,209)(H,210,211)(H4,156,157,159)/t77-,78-,79-,80-,81-,82+,83+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,119-,120-,121-,122-,123-/m0/s1 | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| Purchase
CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | n/a | n/a | 0.00800 | n/a | n/a | n/a | n/a |
Novo Nordisk Als
Curated by ChEMBL
| Assay Description
Agonist activity at human GLP1 receptor expressed in BHK cells assessed as cAMP accumulation |
Proc Natl Acad Sci USA 104: 937-42 (2007)
Article DOI: 10.1073/pnas.0605701104
BindingDB Entry DOI: 10.7270/Q21R6RD8 |
More data for this
Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50109541
(2-Ethoxy-3-{4-[2-(11H-5-oxa-10-thia-dibenzo[a,d]cy...)Show SMILES CCOC(Cc1ccc(OCCC2Sc3ccccc3Oc3ccccc23)cc1)C(O)=O Show InChI InChI=1S/C26H26O5S/c1-2-29-23(26(27)28)17-18-11-13-19(14-12-18)30-16-15-24-20-7-3-4-8-21(20)31-22-9-5-6-10-25(22)32-24/h3-14,23-24H,2,15-17H2,1H3,(H,27,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Patents
| PubMed
| n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Novo Nordisk A/S
Curated by ChEMBL
| Assay Description
In vitro transactivation using receptor transactivation assay against hPPAR gamma |
J Med Chem 45: 789-804 (2002)
BindingDB Entry DOI: 10.7270/Q2445KSG |
More data for this
Ligand-Target Pair | |
Search and Browse
