Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine protease 1 (Bos taurus (bovine)) | BDBM50124947 (CHEMBL453539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Inhibition of bovine beta-trypsin type-3 using L-BAPNA as substrate preincubated for 5 mins followed by substrate addition measured over 60 mins | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50124947 (CHEMBL453539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Inhibition of bovine beta-trypsin using N-t-Boc Gln-Ala-Arg-AMC as substrate preincubated with enzyme followed by substrate addition by Dixon plot an... | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50124947 (CHEMBL453539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Inhibition of bovine beta-trypsin using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by Dixon plo... | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50233907 (CHEMBL4102547) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Inhibition of bovine beta-trypsin using BAPNA as substrate preincubated for 15 mins followed by substrate addition measured over 60 mins by Dixon plo... | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease 1 (Bos taurus (bovine)) | BDBM50124947 (CHEMBL453539) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Inhibition of bovine beta-trypsin | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261301 (CHEMBL4072422) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261322 (CHEMBL4060424) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261327 (CHEMBL4083286) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261309 (CHEMBL4091125) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 63 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261311 (CHEMBL4076718) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261321 (CHEMBL4061450) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 157 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261308 (CHEMBL4099864) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 174 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261307 (CHEMBL4081862) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 177 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261326 (CHEMBL4064091) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 5 (Homo sapiens (Human)) | BDBM50261300 (CHEMBL4084362) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 403 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Negative allosteric modulation of human recombinant mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium mobilization... | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B1 bradykinin receptor (Homo sapiens (Human)) | BDBM50233905 (CHEMBL384721) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 990 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Antagonist activity against bradykinin B1 receptor in human HeLa cells assessed as inhibition of Des-Arg9-BK-induced increase in intracellular Ca2+ l... | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B1 bradykinin receptor (Homo sapiens (Human)) | BDBM50233907 (CHEMBL4102547) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Antagonist activity against bradykinin B1 receptor in human HeLa cells assessed as inhibition of Des-Arg9-BK-induced increase in intracellular Ca2+ l... | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
B1 bradykinin receptor (Homo sapiens (Human)) | BDBM50233906 (CHEMBL4074308) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4.04E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Technological University Curated by ChEMBL | Assay Description Antagonist activity against bradykinin B1 receptor in human HeLa cells assessed as inhibition of Des-Arg9-BK-induced increase in intracellular Ca2+ l... | J Med Chem 60: 504-510 (2017) Article DOI: 10.1021/acs.jmedchem.6b01011 BindingDB Entry DOI: 10.7270/Q2RJ4MRS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of human ERG | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2A6 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50261324 (CHEMBL4098822) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 3A4 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C19 in human liver microsomes using (S)-mephenytoin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C8 in human liver microsomes using amodiaquine as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 1A2 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2C9 (Homo sapiens (Human)) | BDBM50261310 (CHEMBL4102181) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2C9 in human liver microsomes using diclofenac as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2A6 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2A6 (Homo sapiens (Human)) | BDBM50261325 (CHEMBL4060556) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50261323 (CHEMBL4087545) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >5.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Sumitomo Dainippon Pharma Curated by ChEMBL | Assay Description Inhibition of CYP2D6 in human liver microsomes using bufuralol as substrate after 10 mins by LC-MS/MS analysis | Bioorg Med Chem Lett 27: 4331-4335 (2017) Article DOI: 10.1016/j.bmcl.2017.08.030 BindingDB Entry DOI: 10.7270/Q2C53P8R | |||||||||||
More data for this Ligand-Target Pair |
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