Found 130 hits with Last Name = 'tallman' and Initial = 'jf' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 0.310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21397
(8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...)Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| PubMed
| 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85136
(CAS_188942 | CHEMBL103772 | NGD 94-1 | NSC_188942)Show InChI InChI=1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 3.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM85136
(CAS_188942 | CHEMBL103772 | NGD 94-1 | NSC_188942)Show InChI InChI=1S/C18H20N6/c1-2-5-15(6-3-1)17-21-13-16(22-17)14-23-9-11-24(12-10-23)18-19-7-4-8-20-18/h1-8,13H,9-12,14H2,(H,21,22) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21398
(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2 | PDB
Reactome pathway KEGG
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| PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)Show SMILES Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| DrugBank PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 | PDB
Reactome pathway KEGG
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| DrugBank PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50001885
((risperidone)3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-...)Show SMILES Cc1nc2CCCCn2c(=O)c1CCN1CCC(CC1)c1noc2cc(F)ccc12 Show InChI InChI=1S/C23H27FN4O2/c1-15-18(23(29)28-10-3-2-4-21(28)25-15)9-13-27-11-7-16(8-12-27)22-19-6-5-17(24)14-20(19)30-26-22/h5-6,14,16H,2-4,7-13H2,1H3 | PDB
Reactome pathway KEGG
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| DrugBank PubMed
| 24.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50001888
((chloropromazine) [3-(2-Chloro-phenothiazin-10-yl)...)Show InChI InChI=1S/C17H19ClN2S/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20/h3-4,6-9,12H,5,10-11H2,1-2H3 | PDB
Reactome pathway KEGG
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| DrugBank PubMed
| 34.3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)Show SMILES CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 |c:8,15| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid UniChem
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| PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Patents
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| PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM22869
(6-chloro-10-(4-methylpiperazin-1-yl)-2,9-diazatric...)Show SMILES CN1CCN(CC1)C1=c2ccccc2=Nc2ccc(Cl)cc2N1 |c:8,15| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,21H,8-11H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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PC cid PC sid UniChem
Patents
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| PubMed
| 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50001859
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM82479
(CAS_132539-06-1 | NSC_4585 | OLANZAPINE | USRE4934...)Show SMILES CN1CCN(CC1)C1=c2cc(C)sc2=Nc2ccccc2N1 |c:8,15| Show InChI InChI=1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,18H,7-10H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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PC cid PC sid UniChem
Patents
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| 102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50001859
((buspirone) 8-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)...)Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1 Show InChI InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2 | PDB
Reactome pathway KEGG
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| PubMed
| 136 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM84637
(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM79181
(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)Show SMILES CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 Show InChI InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| PubMed
| 158 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
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| DrugBank PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM79181
(10-[3-(4-methyl-1-piperazinyl)propyl]-2-(trifluoro...)Show SMILES CN1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1 Show InChI InChI=1S/C21H24F3N3S/c1-25-11-13-26(14-12-25)9-4-10-27-17-5-2-3-6-19(17)28-20-8-7-16(15-18(20)27)21(22,23)24/h2-3,5-8,15H,4,9-14H2,1H3 | PDB
Reactome pathway KEGG
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Similars
| PubMed
| 197 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM84637
(CAS_85760-74-3 | CHEMBL240773 | NSC_54562 | QUINPI...)Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 250 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM55121
(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)Show InChI InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| DrugBank PubMed
| 407 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM78576
(CIS-THIOTHIXENE | MLS000028463 | SMR000058396 | TH...)Show SMILES CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 Show InChI InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM78576
(CIS-THIOTHIXENE | MLS000028463 | SMR000058396 | TH...)Show SMILES CN(C)S(=O)(=O)c1ccc2Sc3ccccc3\C(=C\CCN3CCN(C)CC3)c2c1 Show InChI InChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8- | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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Similars
| PubMed
| 685 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM11638
(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| 800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM11638
(CHEMBL26 | Compound 7 | N-[(1-ethylpyrrolidin-2-yl...)Show InChI InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50020222
((+/-)-7-(dipropylamino)-5,6,7,8-tetrahydronaphthal...)Show InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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| PubMed
| 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM82247
(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| PubMed
| 2.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50005118
((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)Show InChI InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 2.86E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM50005118
((S)-3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)...)Show InChI InChI=1S/C15H20Cl2N2O3/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2/h7,9,20H,3-6,8H2,1-2H3,(H,18,21)/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 2.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM82247
(8-Chloro-3-methyl-5-phenyl-2,3,4,5-tetrahydro-1H-b...)Show InChI InChI=1S/C17H18ClNO/c1-19-8-7-13-9-16(18)17(20)10-14(13)15(11-19)12-5-3-2-4-6-12/h2-6,9-10,15,20H,7-8,11H2,1H3/t15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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| 3.17E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21393
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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Similars
| PubMed
| 6.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
D(4) dopamine receptor
(Homo sapiens (Human)) | BDBM21393
(7-(dipropylamino)-5,6,7,8-tetrahydronaphthalen-1-o...)Show InChI InChI=1S/C16H25NO/c1-3-10-17(11-4-2)14-9-8-13-6-5-7-16(18)15(13)12-14/h5-7,14,18H,3-4,8-12H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
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| PubMed
| 7.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 282: 1011-9 (1997)
BindingDB Entry DOI: 10.7270/Q2CC0Z63 |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-5
(Homo sapiens (Human)) | BDBM50120777
(8-(3-Fluoro-benzoyl)-2-(2-fluoro-phenyl)-6,7,8,9-t...)Show SMILES Fc1cccc(c1)C(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C22H16F2N4O2/c23-14-5-3-4-13(10-14)21(29)27-9-8-18-16(11-27)20-25-19(12-28(20)22(30)26-18)15-6-1-2-7-17(15)24/h1-7,10,12H,8-9,11H2,(H,26,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 38 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50120783
(8-Benzyl-2-(2-fluoro-phenyl)-6,7,8,9-tetrahydro-5H...)Show SMILES Fc1ccccc1-c1cn2c(n1)c1CN(Cc3ccccc3)CCc1[nH]c2=O Show InChI InChI=1S/C22H19FN4O/c23-18-9-5-4-8-16(18)20-14-27-21(24-20)17-13-26(11-10-19(17)25-22(27)28)12-15-6-2-1-3-7-15/h1-9,14H,10-13H2,(H,25,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-3
(Homo sapiens (Human)) | BDBM26266
(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
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Similars
| DrugBank PDB PubMed
| n/a | n/a | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Gamma-aminobutyric acid receptor subunit alpha-3
(Homo sapiens (Human)) | BDBM50120799
(8-(3,4-Difluoro-benzoyl)-2-(2-fluoro-phenyl)-6,7,8...)Show SMILES Fc1ccc(cc1F)C(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C22H15F3N4O2/c23-15-4-2-1-3-13(15)19-11-29-20(26-19)14-10-28(8-7-18(14)27-22(29)31)21(30)12-5-6-16(24)17(25)9-12/h1-6,9,11H,7-8,10H2,(H,27,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 148 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-2
(Homo sapiens (Human)) | BDBM50120805
(2-(2-Fluoro-phenyl)-8-propenyl-6,7,8,9-tetrahydro-...)Show InChI InChI=1S/C18H17FN4O/c1-2-8-22-9-7-15-13(10-22)17-20-16(11-23(17)18(24)21-15)12-5-3-4-6-14(12)19/h2-6,11H,1,7-10H2,(H,21,24) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 284 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-5
(Homo sapiens (Human)) | BDBM50120798
(2-(2-Fluoro-phenyl)-8-(3H-imidazol-4-ylmethyl)-6,7...)Show SMILES Fc1ccccc1-c1cn2c(n1)c1CN(Cc3cnc[nH]3)CCc1[nH]c2=O Show InChI InChI=1S/C19H17FN6O/c20-15-4-2-1-3-13(15)17-10-26-18(23-17)14-9-25(8-12-7-21-11-22-12)6-5-16(14)24-19(26)27/h1-4,7,10-11H,5-6,8-9H2,(H,21,22)(H,24,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 439 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-5
(Homo sapiens (Human)) | BDBM50120799
(8-(3,4-Difluoro-benzoyl)-2-(2-fluoro-phenyl)-6,7,8...)Show SMILES Fc1ccc(cc1F)C(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C22H15F3N4O2/c23-15-4-2-1-3-13(15)19-11-29-20(26-19)14-10-28(8-7-18(14)27-22(29)31)21(30)12-5-6-16(24)17(25)9-12/h1-6,9,11H,7-8,10H2,(H,27,31) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 491 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-3
(Homo sapiens (Human)) | BDBM50001728
(8-Chloro-1-methyl-6-phenyl-4H-s-triazolo(4,3-a)(1,...)Show SMILES Cc1nnc2CN=C(c3ccccc3)c3cc(Cl)ccc3-n12 |t:6| Show InChI InChI=1S/C17H13ClN4/c1-11-20-21-16-10-19-17(12-5-3-2-4-6-12)14-9-13(18)7-8-15(14)22(11)16/h2-9H,10H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PubMed
| n/a | n/a | n/a | n/a | 69 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-5
(Homo sapiens (Human)) | BDBM26266
(Ambien | CHEMBL911 | Dalparan | N,N-dimethyl-2-[6-...)Show InChI InChI=1S/C19H21N3O/c1-13-5-8-15(9-6-13)19-16(11-18(23)21(3)4)22-12-14(2)7-10-17(22)20-19/h5-10,12H,11H2,1-4H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | >3.00E+3 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-2
(Homo sapiens (Human)) | BDBM50120790
(8-Benzyl-2-(2,5-difluoro-phenyl)-6,7,8,9-tetrahydr...)Show SMILES Fc1ccc(F)c(c1)-c1cn2c(n1)c1CN(Cc3ccccc3)CCc1[nH]c2=O Show InChI InChI=1S/C22H18F2N4O/c23-15-6-7-18(24)16(10-15)20-13-28-21(25-20)17-12-27(9-8-19(17)26-22(28)29)11-14-4-2-1-3-5-14/h1-7,10,13H,8-9,11-12H2,(H,26,29) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 188 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-2
(Homo sapiens (Human)) | BDBM50120799
(8-(3,4-Difluoro-benzoyl)-2-(2-fluoro-phenyl)-6,7,8...)Show SMILES Fc1ccc(cc1F)C(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C22H15F3N4O2/c23-15-4-2-1-3-13(15)19-11-29-20(26-19)14-10-28(8-7-18(14)27-22(29)31)21(30)12-5-6-16(24)17(25)9-12/h1-6,9,11H,7-8,10H2,(H,27,31) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 238 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-2
(Homo sapiens (Human)) | BDBM50120781
(8-Benzyl-2-(3-fluoro-phenyl)-6,7,8,9-tetrahydro-5H...)Show SMILES Fc1cccc(c1)-c1cn2c(n1)c1CN(Cc3ccccc3)CCc1[nH]c2=O Show InChI InChI=1S/C22H19FN4O/c23-17-8-4-7-16(11-17)20-14-27-21(24-20)18-13-26(10-9-19(18)25-22(27)28)12-15-5-2-1-3-6-15/h1-8,11,14H,9-10,12-13H2,(H,25,28) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 154 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-3
(Homo sapiens (Human)) | BDBM50120772
(2-(2-Fluoro-phenyl)-8-propionyl-6,7,8,9-tetrahydro...)Show SMILES CCC(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C18H17FN4O2/c1-2-16(24)22-8-7-14-12(9-22)17-20-15(10-23(17)18(25)21-14)11-5-3-4-6-13(11)19/h3-6,10H,2,7-9H2,1H3,(H,21,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 116 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-5
(Homo sapiens (Human)) | BDBM50120795
(2-(2-Fluoro-phenyl)-8-(2-methyl-benzoyl)-6,7,8,9-t...)Show SMILES Cc1ccccc1C(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C23H19FN4O2/c1-14-6-2-3-7-15(14)22(29)27-11-10-19-17(12-27)21-25-20(13-28(21)23(30)26-19)16-8-4-5-9-18(16)24/h2-9,13H,10-12H2,1H3,(H,26,30) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| n/a | n/a | n/a | n/a | 111 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-3
(Homo sapiens (Human)) | BDBM50120785
(8-Acetyl-2-(2-fluoro-phenyl)-6,7,8,9-tetrahydro-5H...)Show SMILES CC(=O)N1CCc2[nH]c(=O)n3cc(nc3c2C1)-c1ccccc1F Show InChI InChI=1S/C17H15FN4O2/c1-10(23)21-7-6-14-12(8-21)16-19-15(9-22(16)17(24)20-14)11-4-2-3-5-13(11)18/h2-5,9H,6-8H2,1H3,(H,20,24) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 3 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-1
(Homo sapiens (Human)) | BDBM50120794
(2-(2-Fluoro-phenyl)-8-thiophen-2-ylmethyl-6,7,8,9-...)Show SMILES Fc1ccccc1-c1cn2c(n1)c1CN(Cc3cccs3)CCc1[nH]c2=O Show InChI InChI=1S/C20H17FN4OS/c21-16-6-2-1-5-14(16)18-12-25-19(22-18)15-11-24(10-13-4-3-9-27-13)8-7-17(15)23-20(25)26/h1-6,9,12H,7-8,10-11H2,(H,23,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 107 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 1 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |
Gamma-aminobutyric acid receptor subunit alpha-2
(Homo sapiens (Human)) | BDBM50120794
(2-(2-Fluoro-phenyl)-8-thiophen-2-ylmethyl-6,7,8,9-...)Show SMILES Fc1ccccc1-c1cn2c(n1)c1CN(Cc3cccs3)CCc1[nH]c2=O Show InChI InChI=1S/C20H17FN4OS/c21-16-6-2-1-5-14(16)18-12-25-19(22-18)15-11-24(10-13-4-3-9-27-13)8-7-17(15)23-20(25)26/h1-6,9,12H,7-8,10-11H2,(H,23,26) | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| PubMed
| n/a | n/a | n/a | n/a | 67 | n/a | n/a | n/a | n/a |
Neurogen Corporation
Curated by ChEMBL
| Assay Description Effective concentration against gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
J Med Chem 45: 5043-51 (2002)
BindingDB Entry DOI: 10.7270/Q2DR2TTC |
More data for this Ligand-Target Pair | |