BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Gamma-aminobutyric acid receptor subunit alpha-5' and Ligand = 'BDBM26266'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita di Pisa Curated by ChEMBL					Assay Description Displacement of [3H]flumazenil from rat GABA-Aalpha5beta3gamma2 receptor expressed in HEK293 cells				J Med Chem 52: 3723-34 (2009) Article DOI: 10.1021/jm9001154 BindingDB Entry DOI: 10.7270/Q2N58M89
Universita di Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synthélabo Curated by PDSP K_i Database									J Biol Chem 274: 13370-4 (1999) Article DOI: 10.1074/jbc.274.19.13370 BindingDB Entry DOI: 10.7270/Q2765CWZ
Synthélabo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	829	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synthélabo Curated by PDSP K_i Database									J Biol Chem 274: 13370-4 (1999) Article DOI: 10.1074/jbc.274.19.13370 BindingDB Entry DOI: 10.7270/Q2765CWZ
Synthélabo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synthélabo Curated by PDSP K_i Database									J Biol Chem 274: 13370-4 (1999) Article DOI: 10.1074/jbc.274.19.13370 BindingDB Entry DOI: 10.7270/Q2765CWZ
Synthélabo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synthélabo Curated by PDSP K_i Database									J Biol Chem 274: 13370-4 (1999) Article DOI: 10.1074/jbc.274.19.13370 BindingDB Entry DOI: 10.7270/Q2765CWZ
Synthélabo Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Research Laboratories Curated by PDSP K_i Database									Mol Pharmacol 43: 970-5 (1993) BindingDB Entry DOI: 10.7270/Q2ZS2V1S
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (RAT)	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of KwaZulu-Natal Curated by ChEMBL					Assay Description Displacement of [3H]RO15-1788 from recombinant rat GABAalpha5 receptor expressed in HEK293 cells after 1 hr				Eur J Med Chem 126: 298-352 (2017) Article DOI: 10.1016/j.ejmech.2016.11.019 BindingDB Entry DOI: 10.7270/Q2S184RN
University of KwaZulu-Natal Curated by ChEMBL					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM26266 (Ambien \| CHEMBL911 \| Dalparan \| N,N-dimethyl-2-[6-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+3	n/a	n/a	n/a	n/a
Neurogen Corporation Curated by ChEMBL					Assay Description Effective concentration against Gamma-aminobutyric acid A receptor, alpha 5				J Med Chem 45: 5043-51 (2002) BindingDB Entry DOI: 10.7270/Q2DR2TTC
Neurogen Corporation Curated by ChEMBL					More data for this Ligand-Target Pair