Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50004952 (3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 1.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by homologous competition binding assay in presence o... | ACS Med Chem Lett 5: 326-30 (2014) Article DOI: 10.1021/ml400399f BindingDB Entry DOI: 10.7270/Q2445P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50010475 (GAVESTINEL | GV-150526X) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem | Article PubMed | 1.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay | ACS Med Chem Lett 5: 326-30 (2014) Article DOI: 10.1021/ml400399f BindingDB Entry DOI: 10.7270/Q2445P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50004952 (3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 2.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by competition binding assay | ACS Med Chem Lett 5: 326-30 (2014) Article DOI: 10.1021/ml400399f BindingDB Entry DOI: 10.7270/Q2445P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50023198 (8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 4.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay | ACS Med Chem Lett 5: 326-30 (2014) Article DOI: 10.1021/ml400399f BindingDB Entry DOI: 10.7270/Q2445P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50052024 (CHEMBL787 | montelukast) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 6.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assay | ACS Med Chem Lett 5: 326-30 (2014) Article DOI: 10.1021/ml400399f BindingDB Entry DOI: 10.7270/Q2445P0D | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Uracil nucleotide/cysteinyl leukotriene receptor (Homo sapiens (Human)) | BDBM50004952 (3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.26E+3 | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Binding affinity to human GPR17 expressed in CHO-K1 cell membranes after 60 mins by saturation curve study | ACS Med Chem Lett 5: 326-30 (2014) Article DOI: 10.1021/ml400399f BindingDB Entry DOI: 10.7270/Q2445P0D | |||||||||||
More data for this Ligand-Target Pair |