Found 5 hits with Last Name = 'tomaszewska' and Initial = 'a' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Bis(5'-adenosyl)-triphosphatase
(Homo sapiens (Human)) | BDBM50350512
(CHEMBL1812070)Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OCC(COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)OP(O)(S)=O)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C23H33N10O15P3S3/c24-18-12-20(28-5-26-18)32(7-30-12)22-16(36)14(34)10(46-22)3-44-50(40,53)42-1-9(48-49(38,39)52)2-43-51(41,54)45-4-11-15(35)17(37)23(47-11)33-8-31-13-19(25)27-6-29-21(13)33/h5-11,14-17,22-23,34-37H,1-4H2,(H,40,53)(H,41,54)(H2,24,26,28)(H2,25,27,29)(H2,38,39,52)/t9?,10-,11-,14-,15-,16-,17-,22-,23-,50?,51?/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Fragile histidine triad prorein hydrolytic activity |
Bioorg Med Chem 19: 5053-60 (2011)
Article DOI: 10.1016/j.bmc.2011.06.028
BindingDB Entry DOI: 10.7270/Q28K79GM |
More data for this
Ligand-Target Pair | |
Bis(5'-adenosyl)-triphosphatase
(Homo sapiens (Human)) | BDBM50350513
(CHEMBL1812069)Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OCC(COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)OP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C33H44N15O18P3S3/c34-25-16-28(40-6-37-25)46(9-43-16)31-22(52)19(49)13(63-31)3-60-67(55,70)58-1-12(66-69(57,72)62-5-15-21(51)24(54)33(65-15)48-11-45-18-27(36)39-8-42-30(18)48)2-59-68(56,71)61-4-14-20(50)23(53)32(64-14)47-10-44-17-26(35)38-7-41-29(17)47/h6-15,19-24,31-33,49-54H,1-5H2,(H,55,70)(H,56,71)(H,57,72)(H2,34,37,40)(H2,35,38,41)(H2,36,39,42)/t12?,13-,14-,15-,19-,20-,21-,22-,23-,24-,31-,32-,33-,67?,68?,69?/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Fragile histidine triad prorein hydrolytic activity |
Bioorg Med Chem 19: 5053-60 (2011)
Article DOI: 10.1016/j.bmc.2011.06.028
BindingDB Entry DOI: 10.7270/Q28K79GM |
More data for this
Ligand-Target Pair | |
Bis(5'-adenosyl)-triphosphatase
(Homo sapiens (Human)) | BDBM50350516
(CHEMBL1812066)Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OCC(O)COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C23H32N10O13P2S2/c24-18-12-20(28-5-26-18)32(7-30-12)22-16(37)14(35)10(45-22)3-43-47(39,49)41-1-9(34)2-42-48(40,50)44-4-11-15(36)17(38)23(46-11)33-8-31-13-19(25)27-6-29-21(13)33/h5-11,14-17,22-23,34-38H,1-4H2,(H,39,49)(H,40,50)(H2,24,26,28)(H2,25,27,29)/t9?,10-,11-,14-,15-,16-,17-,22-,23-,47?,48?/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Fragile histidine triad prorein hydrolytic activity |
Bioorg Med Chem 19: 5053-60 (2011)
Article DOI: 10.1016/j.bmc.2011.06.028
BindingDB Entry DOI: 10.7270/Q28K79GM |
More data for this
Ligand-Target Pair | |
Bis(5'-adenosyl)-triphosphatase
(Homo sapiens (Human)) | BDBM50350515
(CHEMBL1812067)Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OCC(COP(O)(S)=O)(COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C35H49N15O21P4S4/c36-26-17-29(42-8-39-26)48(11-45-17)32-23(54)20(51)14(69-32)1-62-73(59,77)66-5-35(4-65-72(57,58)76,6-67-74(60,78)63-2-15-21(52)24(55)33(70-15)49-12-46-18-27(37)40-9-43-30(18)49)7-68-75(61,79)64-3-16-22(53)25(56)34(71-16)50-13-47-19-28(38)41-10-44-31(19)50/h8-16,20-25,32-34,51-56H,1-7H2,(H,59,77)(H,60,78)(H,61,79)(H2,36,39,42)(H2,37,40,43)(H2,38,41,44)(H2,57,58,76)/t14-,15-,16-,20-,21-,22-,23-,24-,25-,32-,33-,34-,35?,73?,74?,75?/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Fragile histidine triad prorein hydrolytic activity |
Bioorg Med Chem 19: 5053-60 (2011)
Article DOI: 10.1016/j.bmc.2011.06.028
BindingDB Entry DOI: 10.7270/Q28K79GM |
More data for this
Ligand-Target Pair | |
Bis(5'-adenosyl)-triphosphatase
(Homo sapiens (Human)) | BDBM50350514
(CHEMBL1812068)Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(S)(=O)OCC(COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)(COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)COP(S)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| Show InChI InChI=1S/C45H60N20O24P4S4/c46-33-21-37(54-9-50-33)62(13-58-21)41-29(70)25(66)17(86-41)1-78-90(74,94)82-5-45(6-83-91(75,95)79-2-18-26(67)30(71)42(87-18)63-14-59-22-34(47)51-10-55-38(22)63,7-84-92(76,96)80-3-19-27(68)31(72)43(88-19)64-15-60-23-35(48)52-11-56-39(23)64)8-85-93(77,97)81-4-20-28(69)32(73)44(89-20)65-16-61-24-36(49)53-12-57-40(24)65/h9-20,25-32,41-44,66-73H,1-8H2,(H,74,94)(H,75,95)(H,76,96)(H,77,97)(H2,46,50,54)(H2,47,51,55)(H2,48,52,56)(H2,49,53,57)/t17-,18-,19-,20-,25-,26-,27-,28-,29-,30-,31-,32-,41-,42-,43-,44-,45?,90?,91?,92?,93?/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 35 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Polish Academy of Sciences
Curated by ChEMBL
| Assay Description
Inhibition of Fragile histidine triad prorein hydrolytic activity |
Bioorg Med Chem 19: 5053-60 (2011)
Article DOI: 10.1016/j.bmc.2011.06.028
BindingDB Entry DOI: 10.7270/Q28K79GM |
More data for this
Ligand-Target Pair | |
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