Compile Data Set for Download or QSAR

Found 427 hits with Last Name = 'tsuchiya' and Initial = 's'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM597927 (US11608347, Example 55 | [(7R,9aR)-7-(3-chloro-4- ...) Show SMILES COc1cccc(C(=O)N2CCN3C[C@H](CC[C@@H]3C2)c2ccc(F)c(Cl)c2)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597939 ((4-chlorothieno[2,3- b]pyridin-5-yl)-[rac- (7R,9aR...) Show SMILES Fc1ccc(cc1Cl)[C@H]1CC[C@@H]2CN(CCN2C1)C(=O)c1cnc2sccc2c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597917 (US11608347, Example 46 | [(7R,9aR)-7-(3,4- dichlor...) Show SMILES COc1cccc(C(=O)N2CCN3C[C@H](CC[C@@H]3C2)c2ccc(Cl)c(Cl)c2)c1Br |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561384 (US11390610, Example 213) Show SMILES CCC1(CC)CCN(C1)c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597939 ((4-chlorothieno[2,3- b]pyridin-5-yl)-[rac- (7R,9aR...) Show SMILES Fc1ccc(cc1Cl)[C@H]1CC[C@@H]2CN(CCN2C1)C(=O)c1cnc2sccc2c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561025 (US11390610, Example 67) Show SMILES CC(C)(C)Cc1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561355 (US11390610, Example 184) Show SMILES Clc1cccc(OCc2ccc(cc2Cl)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561217 (US11390610, Example 116) Show SMILES Clc1ccc(cc1Cl)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597977 ((2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-ch...) Show SMILES COc1cccc(C(=O)N2CCN3C[C@](F)(CC[C@@H]3C2)c2ccc(Cl)cc2)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561381 (US11390610, Example 210) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CCC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597953 ((4-chloro-3-methyl-1H- indazol-5-yl)-[rac-(7R,9aR)...) Show SMILES Cc1n[nH]c2ccc(C(=O)N3CCN4C[C@H](CC[C@@H]4C3)c3ccc(F)c(Cl)c3)c(Cl)c12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561367 (US11390610, Example 196) Show SMILES CC(C)(C)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccc(Cl)cc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561341 (US11390610, Example 170) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CCC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597969 ((2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-ch...) Show SMILES COc1cccc(C(=O)N2CCN3C[C@](O)(CC[C@@H]3C2)c2ccc(Cl)cc2)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561328 (US11390610, Example 157) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CC2(C1)CCCC2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561382 (US11390610, Example 211) Show SMILES CC(C)(COCc1ccccc1)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597949 ((4-chloro-1H-indazol-5-yl)- [rac-(7R,9aR)-7-(3-chl...) Show SMILES Fc1ccc(cc1Cl)[C@H]1CC[C@@H]2CN(CCN2C1)C(=O)c1ccc2[nH]ncc2c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561368 (US11390610, Example 197) Show SMILES CC1(C)CCN(C1)c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597950 (US11608347, Example 66 | US11608347, Example 66-B ...) Show SMILES FC(F)Oc1cccc(C(=O)N2CCN3C[C@H](CC[C@@H]3C2)c2ccc(F)c(Cl)c2)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561363 (US11390610, Example 192) Show SMILES Clc1cc(ccc1C#N)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561375 (US11390610, Example 204) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc2nc(oc2c1)N1CC2(CCC2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597945 (US11608347, Example 63-B | [(7S,9aS)-7-(3-chloro-4...) Show SMILES Fc1ccc(cc1Cl)[C@@H]1CC[C@H]2CN(CCN2C1)C(=O)c1cnc2sccc2c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597969 ((2-chloro-3- methoxyphenyl)-[rac- (7R,9aS)-7-(4-ch...) Show SMILES COc1cccc(C(=O)N2CCN3C[C@](O)(CC[C@@H]3C2)c2ccc(Cl)cc2)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561019 (US11390610, Example 61) Show SMILES Clc1cccc(c1)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561038 (US11390610, Example 75) Show SMILES CC(C)(C)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560942 (US11390610, Example 1 | US11390610, Example 160) Show SMILES CC(=O)N(CCc1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)Cc1cccc(c1)C(F)(F)F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561299 (US11390610, Example 128) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1ccc(cc1)N1CC2(C1)CCCC2 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561046 (US11390610, Example 83) Show SMILES FC(F)(F)Oc1cccc(c1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561034 (US11390610, Example 73) Show SMILES Cc1cc(ccc1OCc1cccc(Cl)c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561373 (US11390610, Example 202) Show SMILES FC1(F)CC2(CN(C2)c2nc3ccc(cc3o2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561068 (US11390610, Example 96) Show SMILES Fc1cc(ccc1-c1cccc(c1)C(F)(F)F)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561362 (US11390610, Example 191) Show SMILES CC(C)(CF)c1nc(no1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561020 (US11390610, Example 62) Show SMILES FC(F)(F)c1cccc(c1)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561364 (US11390610, Example 193) Show SMILES CC(C)(C)c1noc(n1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597950 (US11608347, Example 66 | US11608347, Example 66-B ...) Show SMILES FC(F)Oc1cccc(C(=O)N2CCN3C[C@H](CC[C@@H]3C2)c2ccc(F)c(Cl)c2)c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561099 (US11390610, Example 112) Show SMILES CC1(C)CCN(CC1)c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597864 (US11608347, Example 3 | [(7R,9aR)-7-(4- chlorophen...) Show SMILES COc1cccc(C(=O)N2CCN3C[C@H](CC[C@@H]3C2)c2ccc(Cl)cc2)c1Br |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair				3D Structure (crystal)
Monoglyceride lipase (Homo sapiens (Human))	BDBM561024 (US11390610, Example 66) Show SMILES Clc1cccc(COc2ccc(cc2Cl)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597957 ((4-chloro-3-methyl-1H- indazol-5-yl)-[rac-(7R,9aS)...) Show SMILES Cc1n[nH]c2ccc(C(=O)N3CCN4C[C@](O)(CC[C@@H]4C3)c3ccc(Cl)cc3)c(Cl)c12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30.1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597931 ((4-chloro-1H-pyrazolo[3,4- b]pyridin-5-yl)-[rac- (...) Show SMILES Fc1ccc(cc1Cl)[C@H]1CC[C@@H]2CN(CCN2C1)C(=O)c1cnc2[nH]ncc2c1Cl |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561327 (US11390610, Example 156) Show SMILES O=C(N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1)c1cc(N2CCOCC2)c2nc(oc2c1)-c1ccccc1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561033 (US11390610, Example 72) Show SMILES FC(F)(F)c1cc(ccc1OCc1cccc(Cl)c1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561039 (US11390610, Example 76) Show SMILES Clc1cccc(COc2ccc(cc2-c2ncc[nH]2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561366 (2-[4-[3-(3-Chlorophenyl)sulfonyl-3,9-diazaspiro[5....) Show SMILES Clc1cccc(c1)S(=O)(=O)N1CCC2(CCN(CC2)C(=O)N2CCN(CC2)c2nc3ccccc3c(=O)[nH]2)CC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561302 (US11390610, Example 131) Show SMILES Fc1ccc(cc1F)-c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560969 (US11390610, Example 17) Show SMILES FC(F)(F)c1cccc(c1)-c1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM560956 (US11390610, Example 12) Show SMILES Ic1ccccc1CNc1ccc(cc1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597957 ((4-chloro-3-methyl-1H- indazol-5-yl)-[rac-(7R,9aS)...) Show SMILES Cc1n[nH]c2ccc(C(=O)N3CCN4C[C@](O)(CC[C@@H]4C3)c3ccc(Cl)cc3)c(Cl)c12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	38.2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM561329 (US11390610, Example 158) Show SMILES FC1(F)CCC11CN(C1)c1nc2ccc(cc2o1)C(=O)N1CCN(CC1)c1nc2ccccc2c(=O)[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Compounds of the present invention are MAGL inhibitors. Thus, in one aspect, the present invention provides the use of compounds of Formula (I) or a ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2W0994M
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM597946 ((4-chloro-3-methyl- [1,2]oxazolo[5,4-b]pyridin-5- ...) Show SMILES Cc1noc2ncc(C(=O)N3CCN4C[C@H](CC[C@@H]4C3)c3ccc(F)c(Cl)c3)c(Cl)c12 |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39.3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description In one embodiment, the present invention provides compounds of formula (Ie) and their pharmaceutically acceptable salts as described herein, wherein ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2HX1HKS
					More data for this Ligand-Target Pair

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