Compile Data Set for Download or QSAR

Found 184 hits with Last Name = 'tsuzuki' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151765 (US8987445, 201) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(c(Cl)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H23ClF2N2O4S/c1-17-23-5-3-2-4-20(23)15-32-26(17)33(38(36,37)22-11-7-19(8-12-22)27(34)35)16-18-6-13-24(25(29)14-18)28(30,31)21-9-10-21/h2-8,11-15,21H,9-10,16H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151774 (US8987445, 210) Show SMILES Fc1cc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])ccc1C(F)(F)C1CC1 Show InChI InChI=1S/C30H25F3N2O4S.Na/c31-26-15-18(5-14-25(26)30(32,33)22-10-11-22)17-35(40(38,39)23-12-8-20(9-13-23)29(36)37)28-27(19-6-7-19)24-4-2-1-3-21(24)16-34-28;/h1-5,8-9,12-16,19,22H,6-7,10-11,17H2,(H,36,37);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151797 (US8987445, 233) Show SMILES FC(F)(F)c1c(ncc2ccccc12)N(Cc1ccc(c(Cl)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na] Show InChI InChI=1S/C28H20ClF5N2O4S.Na/c29-23-13-16(5-12-22(23)27(30,31)19-8-9-19)15-36(41(39,40)20-10-6-17(7-11-20)26(37)38)25-24(28(32,33)34)21-4-2-1-3-18(21)14-35-25;/h1-7,10-14,19H,8-9,15H2,(H,37,38);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151677 (US8987445, 104) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C27H21F3N2O5S/c28-27(29,30)37-21-11-5-17(6-12-21)16-32(38(35,36)22-13-9-19(10-14-22)26(33)34)25-24(18-7-8-18)23-4-2-1-3-20(23)15-31-25/h1-6,9-15,18H,7-8,16H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	MCE PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151773 (US8987445, 209) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(cc1)C(F)(F)C1(C)CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H26F2N2O4S/c1-19-25-6-4-3-5-22(25)17-32-26(19)33(38(36,37)24-13-9-21(10-14-24)27(34)35)18-20-7-11-23(12-8-20)29(30,31)28(2)15-16-28/h3-14,17H,15-16,18H2,1-2H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151745 (US8987445, 181) Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(c(Cl)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C31H27ClF2N2O4S/c1-18-24-4-2-3-5-25(24)28(20-7-8-20)35-29(18)36(41(39,40)23-13-9-21(10-14-23)30(37)38)17-19-6-15-26(27(32)16-19)31(33,34)22-11-12-22/h2-6,9-10,13-16,20,22H,7-8,11-12,17H2,1H3,(H,37,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151748 (US8987445, 184) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1cc2c(F)cc(F)cc2s1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C28H20F2N2O4S2/c29-19-11-24(30)23-13-20(37-25(23)12-19)15-32(38(35,36)21-9-7-17(8-10-21)28(33)34)27-26(16-5-6-16)22-4-2-1-3-18(22)14-31-27/h1-4,7-14,16H,5-6,15H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151749 (US8987445, 185) Show SMILES FC(F)(C1CC1)c1ccc(CN(c2ncc3ccccc3c2C2CC2)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])cc1Cl Show InChI InChI=1S/C30H25ClF2N2O4S.Na/c31-26-15-18(5-14-25(26)30(32,33)22-10-11-22)17-35(40(38,39)23-12-8-20(9-13-23)29(36)37)28-27(19-6-7-19)24-4-2-1-3-21(24)16-34-28;/h1-5,8-9,12-16,19,22H,6-7,10-11,17H2,(H,36,37);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151655 (US8987445, 61) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc2c(CCC2(C)C)c1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H28N2O4S/c1-19-25-7-5-4-6-23(25)17-30-27(19)31(36(34,35)24-11-9-21(10-12-24)28(32)33)18-20-8-13-26-22(16-20)14-15-29(26,2)3/h4-13,16-17H,14-15,18H2,1-3H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151758 (US8987445, 194) Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2c(F)cc(F)cc2s1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H18F2N2O4S2/c1-15-21-5-3-2-4-17(21)13-29-25(15)30(36(33,34)20-8-6-16(7-9-20)26(31)32)14-19-12-22-23(28)10-18(27)11-24(22)35-19/h2-13H,14H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151766 (US8987445, 202) Show SMILES Cc1cc2ccccc2nc1N(Cc1ccc(c(Cl)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H23ClF2N2O4S/c1-17-14-20-4-2-3-5-25(20)32-26(17)33(38(36,37)22-11-7-19(8-12-22)27(34)35)16-18-6-13-23(24(29)15-18)28(30,31)21-9-10-21/h2-8,11-15,21H,9-10,16H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151767 (US8987445, 203) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(c(F)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H23F3N2O4S/c1-17-23-5-3-2-4-20(23)15-32-26(17)33(38(36,37)22-11-7-19(8-12-22)27(34)35)16-18-6-13-24(25(29)14-18)28(30,31)21-9-10-21/h2-8,11-15,21H,9-10,16H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151786 (US8987445, 222) Show SMILES COC(C)(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1Cl)C(F)(F)F Show InChI InChI=1S/C28H24ClF3N2O5S/c1-17-22-7-5-4-6-20(22)15-33-25(17)34(40(37,38)21-11-9-19(10-12-21)26(35)36)16-18-8-13-23(24(29)14-18)27(2,39-3)28(30,31)32/h4-15H,16H2,1-3H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151799 (US8987445, 235) Show SMILES Fc1cc(CN(c2ncc3ccccc3c2C(F)(F)F)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])ccc1C(F)(F)C1CC1 Show InChI InChI=1S/C28H20F6N2O4S.Na/c29-23-13-16(5-12-22(23)27(30,31)19-8-9-19)15-36(41(39,40)20-10-6-17(7-11-20)26(37)38)25-24(28(32,33)34)21-4-2-1-3-18(21)14-35-25;/h1-7,10-14,19H,8-9,15H2,(H,37,38);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151785 (US8987445, 221) Show SMILES COC(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C28H22F6N2O5S/c1-17-23-6-4-3-5-20(23)15-35-24(17)36(42(39,40)22-13-9-19(10-14-22)25(37)38)16-18-7-11-21(12-8-18)26(41-2,27(29,30)31)28(32,33)34/h3-15H,16H2,1-2H3,(H,37,38)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151753 (US8987445, 189) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(cc1)C(F)(F)C1CCC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H26F2N2O4S/c1-19-26-8-3-2-5-22(26)17-32-27(19)33(38(36,37)25-15-11-21(12-16-25)28(34)35)18-20-9-13-24(14-10-20)29(30,31)23-6-4-7-23/h2-3,5,8-17,23H,4,6-7,18H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151636 (US8987445, 23) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(cc1)C(C)(C)C)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H28N2O4S/c1-19-25-8-6-5-7-22(25)17-29-26(19)30(18-20-9-13-23(14-10-20)28(2,3)4)35(33,34)24-15-11-21(12-16-24)27(31)32/h5-17H,18H2,1-4H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151630 (US8987445, 10) Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na] Show InChI InChI=1S/C28H23F3N2O5S.Na/c1-17-23-4-2-3-5-24(23)25(19-8-9-19)32-26(17)33(16-18-6-12-21(13-7-18)38-28(29,30)31)39(36,37)22-14-10-20(11-15-22)27(34)35;/h2-7,10-15,19H,8-9,16H2,1H3,(H,34,35);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151678 (US8987445, 106) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1C(F)(F)F Show InChI InChI=1S/C25H16F6N2O5S/c26-24(27,28)21-20-4-2-1-3-17(20)13-32-22(21)33(14-15-5-9-18(10-6-15)38-25(29,30)31)39(36,37)19-11-7-16(8-12-19)23(34)35/h1-13H,14H2,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151743 (US8987445, 179) Show SMILES Cc1c(ncc2ccccc12)N(C1CCc2cc(OC(F)(F)F)ccc12)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C27H21F3N2O5S/c1-16-22-5-3-2-4-19(22)15-31-25(16)32(38(35,36)21-10-6-17(7-11-21)26(33)34)24-13-8-18-14-20(9-12-23(18)24)37-27(28,29)30/h2-7,9-12,14-15,24H,8,13H2,1H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151760 (US8987445, 196) Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2c(Cl)cccc2s1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H19ClN2O4S2/c1-16-21-6-3-2-5-18(21)14-28-25(16)29(15-19-13-22-23(27)7-4-8-24(22)34-19)35(32,33)20-11-9-17(10-12-20)26(30)31/h2-14H,15H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151716 (US8987445, 151) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cn1)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C26H20F3N3O5S/c27-26(28,29)37-20-10-9-19(30-14-20)15-32(38(35,36)21-11-7-17(8-12-21)25(33)34)24-23(16-5-6-16)22-4-2-1-3-18(22)13-31-24/h1-4,7-14,16H,5-6,15H2,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151718 (US8987445, 154) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(Cc1ccc(OC(F)(F)F)cc1)c1ncc2ccccc2c1Br Show InChI InChI=1S/C24H16BrF3N2O5S/c25-21-20-4-2-1-3-17(20)13-29-22(21)30(14-15-5-9-18(10-6-15)35-24(26,27)28)36(33,34)19-11-7-16(8-12-19)23(31)32/h1-13H,14H2,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151643 (US8987445, 34) Show SMILES COc1nc(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])c(C)c2ccccc12 Show InChI InChI=1S/C26H21F3N2O6S.Na/c1-16-21-5-3-4-6-22(21)24(36-2)30-23(16)31(15-17-7-11-19(12-8-17)37-26(27,28)29)38(34,35)20-13-9-18(10-14-20)25(32)33;/h3-14H,15H2,1-2H3,(H,32,33);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151783 (US8987445, 219) Show SMILES COC(C)(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1F)C(F)(F)F Show InChI InChI=1S/C28H24F4N2O5S/c1-17-22-7-5-4-6-20(22)15-33-25(17)34(40(37,38)21-11-9-19(10-12-21)26(35)36)16-18-8-13-23(24(29)14-18)27(2,39-3)28(30,31)32/h4-15H,16H2,1-3H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151626 (US8987445, 2) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na] Show InChI InChI=1S/C25H19F3N2O5S.Na/c1-16-22-5-3-2-4-19(22)14-29-23(16)30(15-17-6-10-20(11-7-17)35-25(26,27)28)36(33,34)21-12-8-18(9-13-21)24(31)32;/h2-14H,15H2,1H3,(H,31,32);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151789 (US8987445, 225) Show SMILES CC(C)c1nc(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(cc2)C(O)=O)c(C)c2ccccc12 Show InChI InChI=1S/C28H25F3N2O5S/c1-17(2)25-24-7-5-4-6-23(24)18(3)26(32-25)33(16-19-8-12-21(13-9-19)38-28(29,30)31)39(36,37)22-14-10-20(11-15-22)27(34)35/h4-15,17H,16H2,1-3H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151734 (US8987445, 170) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(CC2CC2)c(F)c1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H25FN2O4S/c1-18-25-5-3-2-4-23(25)16-30-27(18)31(36(34,35)24-12-10-21(11-13-24)28(32)33)17-20-8-9-22(26(29)15-20)14-19-6-7-19/h2-5,8-13,15-16,19H,6-7,14,17H2,1H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151768 (US8987445, 204) Show SMILES Cc1cc2ccccc2nc1N(Cc1ccc(c(F)c1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H23F3N2O4S/c1-17-14-20-4-2-3-5-25(20)32-26(17)33(38(36,37)22-11-7-19(8-12-22)27(34)35)16-18-6-13-23(24(29)15-18)28(30,31)21-9-10-21/h2-8,11-15,21H,9-10,16H2,1H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151644 (US8987445, 35) Show SMILES FC(F)(F)Oc1ccc(CN(c2ncc3ccccc3c2Cl)S(=O)(=O)c2ccc(cc2)C(=O)O[Na])cc1 Show InChI InChI=1S/C24H16ClF3N2O5S.Na/c25-21-20-4-2-1-3-17(20)13-29-22(21)30(14-15-5-9-18(10-6-15)35-24(26,27)28)36(33,34)19-11-7-16(8-12-19)23(31)32;/h1-13H,14H2,(H,31,32);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151666 (US8987445, 84) Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2ccccc2s1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na] Show InChI InChI=1S/C26H20N2O4S2.Na/c1-17-23-8-4-2-7-20(23)15-27-25(17)28(16-21-14-19-6-3-5-9-24(19)33-21)34(31,32)22-12-10-18(11-13-22)26(29)30;/h2-15H,16H2,1H3,(H,29,30);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151702 (US8987445, 137) Show SMILES Cc1cccc2cnc(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(cc3)C(O)=O)c(C)c12 Show InChI InChI=1S/C26H21F3N2O5S/c1-16-4-3-5-20-14-30-24(17(2)23(16)20)31(15-18-6-10-21(11-7-18)36-26(27,28)29)37(34,35)22-12-8-19(9-13-22)25(32)33/h3-14H,15H2,1-2H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151787 (US8987445, 223) Show SMILES COC1(CCc2cc(CN(c3ncc4ccccc4c3C)S(=O)(=O)c3ccc(cc3)C(O)=O)ccc12)C(F)(F)F Show InChI InChI=1S/C29H25F3N2O5S/c1-18-24-6-4-3-5-22(24)16-33-26(18)34(40(37,38)23-10-8-20(9-11-23)27(35)36)17-19-7-12-25-21(15-19)13-14-28(25,39-2)29(30,31)32/h3-12,15-16H,13-14,17H2,1-2H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151627 (US8987445, 4) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(OC(F)(F)F)c(F)c1)S(=O)(=O)c1ccc(cc1)C(=O)O[Na] Show InChI InChI=1S/C25H18F4N2O5S.Na/c1-15-20-5-3-2-4-18(20)13-30-23(15)31(37(34,35)19-9-7-17(8-10-19)24(32)33)14-16-6-11-22(21(26)12-16)36-25(27,28)29;/h2-13H,14H2,1H3,(H,32,33);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151697 (US8987445, 132) Show SMILES Cc1c(nc(C2CC2)c2ccccc12)N(Cc1ccc(F)c(c1)C(F)(F)F)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H22F4N2O4S/c1-16-21-4-2-3-5-22(21)25(18-7-8-18)33-26(16)34(15-17-6-13-24(29)23(14-17)28(30,31)32)39(37,38)20-11-9-19(10-12-20)27(35)36/h2-6,9-14,18H,7-8,15H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151757 (US8987445, 193) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(CC2(CC2)C(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C29H25F3N2O4S/c1-19-25-5-3-2-4-23(25)17-33-26(19)34(39(37,38)24-12-10-22(11-13-24)27(35)36)18-21-8-6-20(7-9-21)16-28(14-15-28)29(30,31)32/h2-13,17H,14-16,18H2,1H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151714 (US8987445, 149) Show SMILES COc1c(ncc2ccccc12)N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H19F3N2O6S/c1-35-22-21-5-3-2-4-18(21)14-29-23(22)30(15-16-6-10-19(11-7-16)36-25(26,27)28)37(33,34)20-12-8-17(9-13-20)24(31)32/h2-14H,15H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151763 (US8987445, 199) Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2cccc(Cl)c2s1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H19ClN2O4S2/c1-16-22-7-3-2-5-19(22)14-28-25(16)29(15-20-13-18-6-4-8-23(27)24(18)34-20)35(32,33)21-11-9-17(10-12-21)26(30)31/h2-14H,15H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151746 (US8987445, 182) Show SMILES Cc1cc2ccccc2nc1N(Cc1ccc(cc1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H24F2N2O4S/c1-18-16-21-4-2-3-5-25(21)31-26(18)32(37(35,36)24-14-8-20(9-15-24)27(33)34)17-19-6-10-22(11-7-19)28(29,30)23-12-13-23/h2-11,14-16,23H,12-13,17H2,1H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151750 (BDBM151751 | US8987445, 186) Show SMILES OC(=O)c1ccc(cc1)S(=O)(=O)N(C1CCc2cc(OC(F)(F)F)ccc12)c1ncc2ccccc2c1C1CC1 Show InChI InChI=1S/C29H23F3N2O5S/c30-29(31,32)39-21-10-13-23-19(15-21)9-14-25(23)34(40(37,38)22-11-7-18(8-12-22)28(35)36)27-26(17-5-6-17)24-4-2-1-3-20(24)16-33-27/h1-4,7-8,10-13,15-17,25H,5-6,9,14H2,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151698 (US8987445, 133) Show SMILES Cc1cc2cccc(Cl)c2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H18ClF3N2O5S/c1-15-13-18-3-2-4-21(26)22(18)30-23(15)31(14-16-5-9-19(10-6-16)36-25(27,28)29)37(34,35)20-11-7-17(8-12-20)24(32)33/h2-13H,14H2,1H3,(H,32,33)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151739 (US8987445, 175) Show SMILES Cc1c(ncc2ccccc12)N(Cc1cc2CCCc2c(F)c1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C27H23FN2O4S/c1-17-23-7-3-2-5-21(23)15-29-26(17)30(16-18-13-20-6-4-8-24(20)25(28)14-18)35(33,34)22-11-9-19(10-12-22)27(31)32/h2-3,5,7,9-15H,4,6,8,16H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151761 (US8987445, 197) Show SMILES Cc1c(ncc2ccccc12)N(Cc1sc2ccccc2c1Cl)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C26H19ClN2O4S2/c1-16-20-7-3-2-6-18(20)14-28-25(16)29(15-23-24(27)21-8-4-5-9-22(21)34-23)35(32,33)19-12-10-17(11-13-19)26(30)31/h2-14H,15H2,1H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151637 (US8987445, 24) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(CC2CC2)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H26N2O4S/c1-19-26-5-3-2-4-24(26)17-29-27(19)30(18-22-10-8-21(9-11-22)16-20-6-7-20)35(33,34)25-14-12-23(13-15-25)28(31)32/h2-5,8-15,17,20H,6-7,16,18H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151755 (US8987445, 191) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(cc1)C(F)(F)C1CC1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H24F2N2O4S/c1-18-25-5-3-2-4-21(25)16-31-26(18)32(37(35,36)24-14-8-20(9-15-24)27(33)34)17-19-6-10-22(11-7-19)28(29,30)23-12-13-23/h2-11,14-16,23H,12-13,17H2,1H3,(H,33,34)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151632 (US8987445, 14) Show SMILES CCOC(C)(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C29H27F3N2O5S/c1-4-39-28(3,29(30,31)32)23-13-9-20(10-14-23)18-34(26-19(2)25-8-6-5-7-22(25)17-33-26)40(37,38)24-15-11-21(12-16-24)27(35)36/h5-17H,4,18H2,1-3H3,(H,35,36)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151653 (US8987445, 56) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc2CCCCc2c1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C28H26N2O4S/c1-19-26-9-5-4-8-24(26)17-29-27(19)30(18-20-10-11-21-6-2-3-7-23(21)16-20)35(33,34)25-14-12-22(13-15-25)28(31)32/h4-5,8-17H,2-3,6-7,18H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151672 (US8987445, 96) Show SMILES COC(C)(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(cc2)C(O)=O)cc1)C(F)(F)F Show InChI InChI=1S/C28H25F3N2O5S/c1-18-24-7-5-4-6-21(24)16-32-25(18)33(39(36,37)23-14-10-20(11-15-23)26(34)35)17-19-8-12-22(13-9-19)27(2,38-3)28(29,30)31/h4-16H,17H2,1-3H3,(H,34,35)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151640 (US8987445, 30) Show SMILES Cc1c(ncc2ccccc12)N(Cc1ccc(F)c(c1)C(F)(F)F)S(=O)(=O)c1ccc(cc1)C(=O)O[Na] Show InChI InChI=1S/C25H18F4N2O4S.Na/c1-15-20-5-3-2-4-18(20)13-30-23(15)31(14-16-6-11-22(26)21(12-16)25(27,28)29)36(34,35)19-9-7-17(8-10-19)24(32)33;/h2-13H,14H2,1H3,(H,32,33);/q;+1/p-1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Homo sapiens (Human))	BDBM151633 (US8987445, 17) Show SMILES Cc1cc2ccccc2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(cc1)C(O)=O Show InChI InChI=1S/C25H19F3N2O5S/c1-16-14-19-4-2-3-5-22(19)29-23(16)30(15-17-6-10-20(11-7-17)35-25(26,27)28)36(33,34)21-12-8-18(9-13-21)24(31)32/h2-14H,15H2,1H3,(H,31,32)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	37
Mitsubishi Tanabe Pharma Corporation US Patent					Assay Description The functional activity of compounds was determined by measuring changes in intracellular calcium concentration using a Ca2+ sensitive fluorescent dy...				US Patent US8987445 (2015) BindingDB Entry DOI: 10.7270/Q2BZ64R5
					More data for this Ligand-Target Pair

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