BindingDB PrimarySearch

Found 24 hits with Last Name = 'venkatraman' and Initial = 'ms'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123054 (US8742134, (1)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.160	-55.3	0.230	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123056 (US8742134, (3) \| US8742134, (8)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.180	-55.1	0.25	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123055 (US8742134, (2) \| US8742134, (7)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.180	-55.1	0.25	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123057 (US8742134, (4) \| US8742134, (5) \| US8742134, (6)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.220	-54.6	0.300	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123057 (US8742134, (4) \| US8742134, (5) \| US8742134, (6)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.5	-49.9	2.10	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123057 (US8742134, (4) \| US8742134, (5) \| US8742134, (6)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	2.10	-49.0	2.90	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123055 (US8742134, (2) \| US8742134, (7)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	14	-44.4	19	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM123056 (US8742134, (3) \| US8742134, (8)) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	26	-42.9	36	n/a	n/a	n/a	n/a	n/a	22
Theron Pharmaceuticals, Inc. US Patent					Assay Description Radioligand binding studies were carried out with M3 receptor cell homogenates as described (Peralta et al., The EMBO Journal 6, 3923-3929, (1987)). ...				US Patent US8742134 (2014) BindingDB Entry DOI: 10.7270/Q20000SX
Theron Pharmaceuticals, Inc. US Patent					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190422 (2,2'-[{8-[(2-{4-[(2,4-dDioxo-1,3-thiazolidin-5-yl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	60	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190421 (5-[(4-{2-[5-(1,2-dithiolan-3-yl)pentylmethylamino]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190421 (5-[(4-{2-[5-(1,2-dithiolan-3-yl)pentylmethylamino]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.80E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190430 (4-({3-(acetylthio)-8-[(2-{4-[(2,4-dioxo-1,3-thiazo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	150	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190427 (CHEMBL208601 \| N-(2-{4-[(2,4-dioxo-1,3-thiazolidin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190432 (CHEMBL211237 \| [3-chloro-4-(3-{[5-(1,2-dithiolan-3...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50049240 ((+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)m...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	550	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190428 (CHEMBL379050 \| N-(2-{4-[(2,4-dioxo-1,3-thiazolidin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190425 (CHEMBL209364 \| N-(2-{4-[(2,4-dioxa-1,3-thiazolidin...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190424 (2-({3-(acetylthio)-8-[(2-{4-[(2,4-dioxo-1,3-thiazo...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM28681 (5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	76	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190426 (CHEMBL448790 \| methyl [3-chloro-4-(3-{[5-(1,2-dith...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190421 (5-[(4-{2-[5-(1,2-dithiolan-3-yl)pentylmethylamino]...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190420 (CHEMBL212737 \| S,S'-{8-[(2-{4-[(2,4-dioxo-1,3-thia...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	39	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190419 (4-({8-[(2-{4-[(2,4-dioxo-1,3-thiazolidin-5-yl)meth...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair
Peroxisome proliferator-activated receptor gamma (Homo sapiens (Human))	BDBM50190423 (4,4'-[{8-[(2-{4-[(2,4-dioxo-1,3-thiazolidin-5-yl)m...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
University of Mississippi Curated by ChEMBL					Assay Description Transactivation of PPARgamma in CV1 cells				J Med Chem 49: 4072-84 (2006) Article DOI: 10.1021/jm0510880 BindingDB Entry DOI: 10.7270/Q2PZ59M5
University of Mississippi Curated by ChEMBL					More data for this Ligand-Target Pair