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Compile Data Set for Download or QSAR

Found 31 hits with Last Name = 'wyffels' and Initial = 'l'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414266
PNG
(CHEMBL569596)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1ccc(OC)cc1
Show InChI InChI=1S/C27H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-27(29)28-24-23-25-19-21-26(30-2)22-20-25/h7-8,10-11,19-22H,3-6,9,12-18,23-24H2,1-2H3,(H,28,29)/b8-7-,11-10-
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n/an/a 2.29E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50175105
PNG
((5Z,8Z,11Z,14Z)-N-(4-methoxyphenethyl)icosa-5,8,11...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccc(OC)cc1
Show InChI InChI=1S/C29H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-29(31)30-26-25-27-21-23-28(32-2)24-22-27/h7-8,10-11,13-14,16-17,21-24H,3-6,9,12,15,18-20,25-26H2,1-2H3,(H,30,31)/b8-7-,11-10-,14-13-,17-16-
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n/an/a 2.75E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254201
PNG
(CHEMBL509376 | N-(2-iodethyl)arachidonylamide)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCI
Show InChI InChI=1S/C22H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 3.14E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254201
PNG
(CHEMBL509376 | N-(2-iodethyl)arachidonylamide)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCI
Show InChI InChI=1S/C22H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 4.31E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414268
PNG
(CHEMBL550631)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1cccc(OC)c1
Show InChI InChI=1S/C29H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-29(31)30-25-24-27-21-20-22-28(26-27)32-2/h7-8,10-11,13-14,16-17,20-22,26H,3-6,9,12,15,18-19,23-25H2,1-2H3,(H,30,31)/b8-7-,11-10-,14-13-,17-16-
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n/an/a 4.47E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM29083
PNG
(Impulsin | MimyX | Palmidrol | Palmityoletanolamid...)
Show SMILES CCCCCCCCCCCCCCCC(=O)NCCO
Show InChI InChI=1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)19-16-17-20/h20H,2-17H2,1H3,(H,19,21)
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n/an/a 5.01E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414267
PNG
(CHEMBL550549)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1cccc(OC)c1
Show InChI InChI=1S/C27H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-27(29)28-23-22-25-19-18-20-26(24-25)30-2/h7-8,10-11,18-20,24H,3-6,9,12-17,21-23H2,1-2H3,(H,28,29)/b8-7-,11-10-
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n/an/a 5.62E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254200
PNG
(CHEMBL448660 | N-(2-iodoethyl)linoleoylamide)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCI
Show InChI InChI=1S/C20H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,22,23)/b7-6-,10-9-
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n/an/a 5.78E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254200
PNG
(CHEMBL448660 | N-(2-iodoethyl)linoleoylamide)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCI
Show InChI InChI=1S/C20H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,22,23)/b7-6-,10-9-
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n/an/a 6.20E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254200
PNG
(CHEMBL448660 | N-(2-iodoethyl)linoleoylamide)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCI
Show InChI InChI=1S/C20H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,22,23)/b7-6-,10-9-
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n/an/a 6.66E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated 15 mins before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254200
PNG
(CHEMBL448660 | N-(2-iodoethyl)linoleoylamide)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCI
Show InChI InChI=1S/C20H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,22,23)/b7-6-,10-9-
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n/an/a 7.33E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated 60 mins before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50056471
PNG
((9Z,12Z)-Octadeca-9,12-dienoic acid (2-hydroxy-eth...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h6-7,9-10,22H,2-5,8,11-19H2,1H3,(H,21,23)/b7-6-,10-9-
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n/an/a 7.58E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50056471
PNG
((9Z,12Z)-Octadeca-9,12-dienoic acid (2-hydroxy-eth...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCO
Show InChI InChI=1S/C20H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)21-18-19-22/h6-7,9-10,22H,2-5,8,11-19H2,1H3,(H,21,23)/b7-6-,10-9-
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n/an/a 7.59E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254200
PNG
(CHEMBL448660 | N-(2-iodoethyl)linoleoylamide)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCI
Show InChI InChI=1S/C20H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(23)22-19-18-21/h6-7,9-10H,2-5,8,11-19H2,1H3,(H,22,23)/b7-6-,10-9-
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n/an/a 7.64E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated 30 mins before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254201
PNG
(CHEMBL509376 | N-(2-iodethyl)arachidonylamide)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCI
Show InChI InChI=1S/C22H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 7.93E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated 15 mins before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254201
PNG
(CHEMBL509376 | N-(2-iodethyl)arachidonylamide)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCI
Show InChI InChI=1S/C22H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 9.89E+3n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated 30 mins before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50254201
PNG
(CHEMBL509376 | N-(2-iodethyl)arachidonylamide)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCI
Show InChI InChI=1S/C22H36INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)24-21-20-23/h6-7,9-10,12-13,15-16H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 1.01E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH assessed as [3H]AEA hydrolysis preincubated 60 mins before [3H]AEA substrate addition


Bioorg Med Chem 17: 49-56 (2008)


Article DOI: 10.1016/j.bmc.2008.11.019
BindingDB Entry DOI: 10.7270/Q20C4VMB
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM22988
PNG
((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
Show InChI InChI=1S/C22H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(25)23-20-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-21H2,1H3,(H,23,25)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 1.17E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414261
PNG
(CHEMBL550431)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCc1ccc(I)cc1
Show InChI InChI=1S/C25H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-25(28)27-22-23-18-20-24(26)21-19-23/h6-7,9-10,18-21H,2-5,8,11-17,22H2,1H3,(H,27,28)/b7-6-,10-9-
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n/an/a 1.45E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414271
PNG
(CHEMBL561235)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1cccc(I)c1
Show InChI InChI=1S/C27H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-27(30)29-24-25-20-19-21-26(28)23-25/h6-7,9-10,12-13,15-16,19-21,23H,2-5,8,11,14,17-18,22,24H2,1H3,(H,29,30)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 2.40E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414263
PNG
(CHEMBL560697)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCc1cccc(I)c1
Show InChI InChI=1S/C25H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-25(28)27-22-23-18-17-19-24(26)21-23/h6-7,9-10,17-19,21H,2-5,8,11-16,20,22H2,1H3,(H,27,28)/b7-6-,10-9-
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n/an/a 2.88E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414270
PNG
(CHEMBL550833)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccccc1OC
Show InChI InChI=1S/C29H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-24-29(31)30-26-25-27-22-20-21-23-28(27)32-2/h7-8,10-11,13-14,16-17,20-23H,3-6,9,12,15,18-19,24-26H2,1-2H3,(H,30,31)/b8-7-,11-10-,14-13-,17-16-
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n/an/a 3.47E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414269
PNG
(CHEMBL550831)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1ccccc1OC
Show InChI InChI=1S/C27H43NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22-27(29)28-24-23-25-20-18-19-21-26(25)30-2/h7-8,10-11,18-21H,3-6,9,12-17,22-24H2,1-2H3,(H,28,29)/b8-7-,11-10-
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n/an/a 4.57E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414262
PNG
(CHEMBL560500)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1ccc(I)cc1
Show InChI InChI=1S/C27H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-27(30)29-24-25-20-22-26(28)23-21-25/h6-7,9-10,12-13,15-16,20-23H,2-5,8,11,14,17-19,24H2,1H3,(H,29,30)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 6.17E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414264
PNG
(CHEMBL561236)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCc1ccccc1I
Show InChI InChI=1S/C25H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-25(28)27-22-23-19-17-18-20-24(23)26/h6-7,9-10,17-20H,2-5,8,11-16,21-22H2,1H3,(H,27,28)/b7-6-,10-9-
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n/an/a 8.91E+4n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414260
PNG
(CHEMBL560499)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccccc1I
Show InChI InChI=1S/C28H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-28(31)30-25-24-26-21-19-20-22-27(26)29/h6-7,9-10,12-13,15-16,19-22H,2-5,8,11,14,17-18,23-25H2,1H3,(H,30,31)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 2.51E+5n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414258
PNG
(CHEMBL564039)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1cccc(I)c1
Show InChI InChI=1S/C28H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-28(31)30-24-23-26-20-19-21-27(29)25-26/h6-7,9-10,12-13,15-16,19-21,25H,2-5,8,11,14,17-18,22-24H2,1H3,(H,30,31)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 3.89E+5n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414257
PNG
(CHEMBL550428)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1cccc(I)c1
Show InChI InChI=1S/C26H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-26(29)28-22-21-24-18-17-19-25(27)23-24/h6-7,9-10,17-19,23H,2-5,8,11-16,20-22H2,1H3,(H,28,29)/b7-6-,10-9-
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n/an/a 4.07E+5n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414256
PNG
(CHEMBL550149)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCc1ccc(I)cc1
Show InChI InChI=1S/C28H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(31)30-25-24-26-20-22-27(29)23-21-26/h6-7,9-10,12-13,15-16,20-23H,2-5,8,11,14,17-19,24-25H2,1H3,(H,30,31)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 1.07E+6n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414259
PNG
(CHEMBL561628)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCCc1ccccc1I
Show InChI InChI=1S/C26H40INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-26(29)28-23-22-24-19-17-18-20-25(24)27/h6-7,9-10,17-20H,2-5,8,11-16,21-23H2,1H3,(H,28,29)/b7-6-,10-9-
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n/an/a 1.95E+6n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579]


(Rattus norvegicus (rat))
BDBM50414265
PNG
(CHEMBL565224)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCc1ccccc1I
Show InChI InChI=1S/C27H38INO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23-27(30)29-24-25-21-19-20-22-26(25)28/h6-7,9-10,12-13,15-16,19-22H,2-5,8,11,14,17-18,23-24H2,1H3,(H,29,30)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 6.46E+6n/an/an/an/an/an/a



Ghent University

Curated by ChEMBL


Assay Description
Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEA


J Med Chem 52: 4613-22 (2009)


Article DOI: 10.1021/jm900324e
BindingDB Entry DOI: 10.7270/Q25X2B5M
More data for this
Ligand-Target Pair