Found 49 hits with Last Name = 'yim' and Initial = 'cb' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021498
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:49:48:32:53.36.35,THB:9:8:16:4.5.6| Show InChI InChI=1S/C44H54N4O8/c49-29-7-5-25-19-31-43(53)13-11-27(39-41(43,35(25)37(29)55-39)15-17-47(31)21-23-1-2-23)45-33(51)9-10-34(52)46-28-12-14-44(54)32-20-26-6-8-30(50)38-36(26)42(44,40(28)56-38)16-18-48(32)22-24-3-4-24/h5-8,23-24,27-28,31-32,39-40,49-50,53-54H,1-4,9-22H2,(H,45,51)(H,46,52)/t27-,28-,31?,32?,39+,40+,41?,42?,43-,44-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021500
(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,1...)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |r,THB:10:9:4.5.6:17| Show InChI InChI=1S/C22H28N2O4/c1-12(25)23-15-6-7-22(27)17-10-14-4-5-16(26)19-18(14)21(22,20(15)28-19)8-9-24(17)11-13-2-3-13/h4-5,13,15,17,20,26-27H,2-3,6-11H2,1H3,(H,23,25)/t15-,17-,20+,21+,22-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021495
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:65:64:48:69.52.51,THB:9:8:16:4.5.6| Show InChI InChI=1S/C52H66N8O12/c61-33-7-5-29-19-35-51(69)13-11-31(47-49(51,43(29)45(33)71-47)15-17-59(35)25-27-1-2-27)57-41(67)23-55-39(65)21-53-37(63)9-10-38(64)54-22-40(66)56-24-42(68)58-32-12-14-52(70)36-20-30-6-8-34(62)46-44(30)50(52,48(32)72-46)16-18-60(36)26-28-3-4-28/h5-8,27-28,31-32,35-36,47-48,61-62,69-70H,1-4,9-26H2,(H,53,63)(H,54,64)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t31-,32-,35?,36?,47+,48+,49?,50?,51-,52-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021493
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:73:72:56:77.60.59,THB:9:8:16:4.5.6| Show InChI InChI=1S/C56H72N10O14/c67-35-7-5-31-19-37-55(77)13-11-33(51-53(55,47(31)49(35)79-51)15-17-65(37)27-29-1-2-29)63-45(75)25-61-43(73)23-59-41(71)21-57-39(69)9-10-40(70)58-22-42(72)60-24-44(74)62-26-46(76)64-34-12-14-56(78)38-20-32-6-8-36(68)50-48(32)54(56,52(34)80-50)16-18-66(38)28-30-3-4-30/h5-8,29-30,33-34,37-38,51-52,67-68,77-78H,1-4,9-28H2,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,75)(H,64,76)/t33-,34-,37?,38?,51+,52+,53?,54?,55-,56-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021498
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:49:48:32:53.36.35,THB:9:8:16:4.5.6| Show InChI InChI=1S/C44H54N4O8/c49-29-7-5-25-19-31-43(53)13-11-27(39-41(43,35(25)37(29)55-39)15-17-47(31)21-23-1-2-23)45-33(51)9-10-34(52)46-28-12-14-44(54)32-20-26-6-8-30(50)38-36(26)42(44,40(28)56-38)16-18-48(32)22-24-3-4-24/h5-8,23-24,27-28,31-32,39-40,49-50,53-54H,1-4,9-22H2,(H,45,51)(H,46,52)/t27-,28-,31?,32?,39+,40+,41?,42?,43-,44-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021499
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:57:56:40:61.44.43,THB:9:8:16:4.5.6| Show InChI InChI=1S/C48H60N6O10/c55-31-7-5-27-19-33-47(61)13-11-29(43-45(47,39(27)41(31)63-43)15-17-53(33)23-25-1-2-25)51-37(59)21-49-35(57)9-10-36(58)50-22-38(60)52-30-12-14-48(62)34-20-28-6-8-32(56)42-40(28)46(48,44(30)64-42)16-18-54(34)24-26-3-4-26/h5-8,25-26,29-30,33-34,43-44,55-56,61-62H,1-4,9-24H2,(H,49,57)(H,50,58)(H,51,59)(H,52,60)/t29-,30-,33?,34?,43+,44+,45?,46?,47-,48-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021499
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:57:56:40:61.44.43,THB:9:8:16:4.5.6| Show InChI InChI=1S/C48H60N6O10/c55-31-7-5-27-19-33-47(61)13-11-29(43-45(47,39(27)41(31)63-43)15-17-53(33)23-25-1-2-25)51-37(59)21-49-35(57)9-10-36(58)50-22-38(60)52-30-12-14-48(62)34-20-28-6-8-32(56)42-40(28)46(48,44(30)64-42)16-18-54(34)24-26-3-4-26/h5-8,25-26,29-30,33-34,43-44,55-56,61-62H,1-4,9-24H2,(H,49,57)(H,50,58)(H,51,59)(H,52,60)/t29-,30-,33?,34?,43+,44+,45?,46?,47-,48-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021495
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:65:64:48:69.52.51,THB:9:8:16:4.5.6| Show InChI InChI=1S/C52H66N8O12/c61-33-7-5-29-19-35-51(69)13-11-31(47-49(51,43(29)45(33)71-47)15-17-59(35)25-27-1-2-27)57-41(67)23-55-39(65)21-53-37(63)9-10-38(64)54-22-40(66)56-24-42(68)58-32-12-14-52(70)36-20-30-6-8-34(62)46-44(30)50(52,48(32)72-46)16-18-60(36)26-28-3-4-28/h5-8,27-28,31-32,35-36,47-48,61-62,69-70H,1-4,9-26H2,(H,53,63)(H,54,64)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t31-,32-,35?,36?,47+,48+,49?,50?,51-,52-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021493
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:73:72:56:77.60.59,THB:9:8:16:4.5.6| Show InChI InChI=1S/C56H72N10O14/c67-35-7-5-31-19-37-55(77)13-11-33(51-53(55,47(31)49(35)79-51)15-17-65(37)27-29-1-2-29)63-45(75)25-61-43(73)23-59-41(71)21-57-39(69)9-10-40(70)58-22-42(72)60-24-44(74)62-26-46(76)64-34-12-14-56(78)38-20-32-6-8-36(68)50-48(32)54(56,52(34)80-50)16-18-66(38)28-30-3-4-30/h5-8,29-30,33-34,37-38,51-52,67-68,77-78H,1-4,9-28H2,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,75)(H,64,76)/t33-,34-,37?,38?,51+,52+,53?,54?,55-,56-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 2.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021495
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:65:64:48:69.52.51,THB:9:8:16:4.5.6| Show InChI InChI=1S/C52H66N8O12/c61-33-7-5-29-19-35-51(69)13-11-31(47-49(51,43(29)45(33)71-47)15-17-59(35)25-27-1-2-27)57-41(67)23-55-39(65)21-53-37(63)9-10-38(64)54-22-40(66)56-24-42(68)58-32-12-14-52(70)36-20-30-6-8-34(62)46-44(30)50(52,48(32)72-46)16-18-60(36)26-28-3-4-28/h5-8,27-28,31-32,35-36,47-48,61-62,69-70H,1-4,9-26H2,(H,53,63)(H,54,64)(H,55,65)(H,56,66)(H,57,67)(H,58,68)/t31-,32-,35?,36?,47+,48+,49?,50?,51-,52-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021493
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:73:72:56:77.60.59,THB:9:8:16:4.5.6| Show InChI InChI=1S/C56H72N10O14/c67-35-7-5-31-19-37-55(77)13-11-33(51-53(55,47(31)49(35)79-51)15-17-65(37)27-29-1-2-29)63-45(75)25-61-43(73)23-59-41(71)21-57-39(69)9-10-40(70)58-22-42(72)60-24-44(74)62-26-46(76)64-34-12-14-56(78)38-20-32-6-8-36(68)50-48(32)54(56,52(34)80-50)16-18-66(38)28-30-3-4-30/h5-8,29-30,33-34,37-38,51-52,67-68,77-78H,1-4,9-28H2,(H,57,69)(H,58,70)(H,59,71)(H,60,72)(H,61,73)(H,62,74)(H,63,75)(H,64,76)/t33-,34-,37?,38?,51+,52+,53?,54?,55-,56-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021499
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:57:56:40:61.44.43,THB:9:8:16:4.5.6| Show InChI InChI=1S/C48H60N6O10/c55-31-7-5-27-19-33-47(61)13-11-29(43-45(47,39(27)41(31)63-43)15-17-53(33)23-25-1-2-25)51-37(59)21-49-35(57)9-10-36(58)50-22-38(60)52-30-12-14-48(62)34-20-28-6-8-32(56)42-40(28)46(48,44(30)64-42)16-18-54(34)24-26-3-4-26/h5-8,25-26,29-30,33-34,43-44,55-56,61-62H,1-4,9-24H2,(H,49,57)(H,50,58)(H,51,59)(H,52,60)/t29-,30-,33?,34?,43+,44+,45?,46?,47-,48-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 7.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021490
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:62:61:45:63.49.48,THB:9:8:13:4.5.6| Show InChI InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021498
(1N,4N-di[4-cyclopropylmethyl-10,17-dihydroxy-(13R,...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4CC1CC1)c56)ccc3O |TLB:49:48:32:53.36.35,THB:9:8:16:4.5.6| Show InChI InChI=1S/C44H54N4O8/c49-29-7-5-25-19-31-43(53)13-11-27(39-41(43,35(25)37(29)55-39)15-17-47(31)21-23-1-2-23)45-33(51)9-10-34(52)46-28-12-14-44(54)32-20-26-6-8-30(50)38-36(26)42(44,40(28)56-38)16-18-48(32)22-24-3-4-24/h5-8,23-24,27-28,31-32,39-40,49-50,53-54H,1-4,9-22H2,(H,45,51)(H,46,52)/t27-,28-,31?,32?,39+,40+,41?,42?,43-,44-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021502
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:62:61:45:63.49.48,THB:9:8:13:4.5.6| Show InChI InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021500
(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,1...)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |r,THB:10:9:4.5.6:17| Show InChI InChI=1S/C22H28N2O4/c1-12(25)23-15-6-7-22(27)17-10-14-4-5-16(26)19-18(14)21(22,20(15)28-19)8-9-24(17)11-13-2-3-13/h4-5,13,15,17,20,26-27H,2-3,6-11H2,1H3,(H,23,25)/t15-,17-,20+,21+,22-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021492
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:54:53:37:55.41.40,THB:9:8:13:4.5.6| Show InChI InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021497
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:70:69:53:71.57.56,THB:9:8:13:4.5.6| Show InChI InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 22 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021501
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:46:45:29:47.33.32,THB:9:8:13:4.5.6| Show InChI InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 23 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021496
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:70:69:53:71.57.56,THB:9:8:13:4.5.6| Show InChI InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021490
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:62:61:45:63.49.48,THB:9:8:13:4.5.6| Show InChI InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Compound was tested for binding affinity against delta opioid receptor in guinea pig brain membrane using [3H]-EK as the radioligand |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021496
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:70:69:53:71.57.56,THB:9:8:13:4.5.6| Show InChI InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 34 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021500
(1N-[4-cyclopropylmethyl-10,17-dihydroxy-(13R,14R,1...)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |r,THB:10:9:4.5.6:17| Show InChI InChI=1S/C22H28N2O4/c1-12(25)23-15-6-7-22(27)17-10-14-4-5-16(26)19-18(14)21(22,20(15)28-19)8-9-24(17)11-13-2-3-13/h4-5,13,15,17,20,26-27H,2-3,6-11H2,1H3,(H,23,25)/t15-,17-,20+,21+,22-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021497
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:70:69:53:71.57.56,THB:9:8:13:4.5.6| Show InChI InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021491
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:54:53:37:55.41.40,THB:9:8:13:4.5.6| Show InChI InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 44 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021502
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:62:61:45:63.49.48,THB:9:8:13:4.5.6| Show InChI InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021504
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:46:45:29:47.33.32,THB:9:8:13:4.5.6| Show InChI InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021494
(1N-[10,17-dihydroxy-4-methyl-(13R,14R,17S)-12-oxa-...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |THB:9:8:13:4.5.6| Show InChI InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14?,17+,18?,19-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021492
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:54:53:37:55.41.40,THB:9:8:13:4.5.6| Show InChI InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 86 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021490
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:62:61:45:63.49.48,THB:9:8:13:4.5.6| Show InChI InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 94 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021504
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:46:45:29:47.33.32,THB:9:8:13:4.5.6| Show InChI InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021491
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:54:53:37:55.41.40,THB:9:8:13:4.5.6| Show InChI InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50021503
(1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-...)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(C)=O)ccc3O |r,THB:10:9:14:4.5.6| Show InChI InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14+,17-,18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-naloxone from Opioid receptor mu 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021501
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:46:45:29:47.33.32,THB:9:8:13:4.5.6| Show InChI InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021492
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:54:53:37:55.41.40,THB:9:8:13:4.5.6| Show InChI InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021501
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:46:45:29:47.33.32,THB:9:8:13:4.5.6| Show InChI InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021497
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@]5(O)CC[C@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H]1CC[C@]2(O)[C@H]4Cc5ccc(O)c6O[C@@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:70:69:53:71.57.56,THB:9:8:13:4.5.6| Show InChI InChI=1S/C46H58N8O12/c1-53-15-13-43-37-23-3-5-27(55)39(37)65-41(43)25(9-11-45(43,63)29(53)17-23)51-35(61)21-49-33(59)19-47-31(57)7-8-32(58)48-20-34(60)50-22-36(62)52-26-10-12-46(64)30-18-24-4-6-28(56)40-38(24)44(46,42(26)66-40)14-16-54(30)2/h3-6,25-26,29-30,41-42,55-56,63-64H,7-22H2,1-2H3,(H,47,57)(H,48,58)(H,49,59)(H,50,60)(H,51,61)(H,52,62)/t25-,26-,29?,30?,41-,42-,43?,44?,45+,46+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021502
(1N,4N-di[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:62:61:45:63.49.48,THB:9:8:13:4.5.6| Show InChI InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021503
(1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-...)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(C)=O)ccc3O |r,THB:10:9:14:4.5.6| Show InChI InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14+,17-,18-,19+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 480 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021504
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:46:45:29:47.33.32,THB:9:8:13:4.5.6| Show InChI InChI=1S/C38H46N4O8/c1-41-15-13-35-29-19-3-5-23(43)31(29)49-33(35)21(9-11-37(35,47)25(41)17-19)39-27(45)7-8-28(46)40-22-10-12-38(48)26-18-20-4-6-24(44)32-30(20)36(38,34(22)50-32)14-16-42(26)2/h3-6,21-22,25-26,33-34,43-44,47-48H,7-18H2,1-2H3,(H,39,45)(H,40,46)/t21-,22-,25?,26?,33-,34-,35?,36?,37+,38+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 500 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021491
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:54:53:37:55.41.40,THB:9:8:13:4.5.6| Show InChI InChI=1S/C42H52N6O10/c1-47-15-13-39-33-21-3-5-25(49)35(33)57-37(39)23(9-11-41(39,55)27(47)17-21)45-31(53)19-43-29(51)7-8-30(52)44-20-32(54)46-24-10-12-42(56)28-18-22-4-6-26(50)36-34(22)40(42,38(24)58-36)14-16-48(28)2/h3-6,23-24,27-28,37-38,49-50,55-56H,7-20H2,1-2H3,(H,43,51)(H,44,52)(H,45,53)(H,46,54)/t23-,24-,27?,28?,37-,38-,39?,40?,41+,42+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 590 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(Homo sapiens (Human)) | BDBM50021494
(1N-[10,17-dihydroxy-4-methyl-(13R,14R,17S)-12-oxa-...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |THB:9:8:13:4.5.6| Show InChI InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14?,17+,18?,19-/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-EK from Opioid receptor delta 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021496
(1N,4N-di[10,17-dihydroxy-4-methyl-(13S,14R,17R)-12...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(=O)CNC(=O)CNC(=O)CNC(=O)CCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@H]1CC[C@@]2(O)[C@H]4Cc5ccc(O)c6O[C@]1([H])[C@]2(CCN4C)c56)ccc3O |TLB:70:69:53:71.57.56,THB:9:8:13:4.5.6| Show InChI InChI=1S/C50H64N10O14/c1-59-15-13-47-41-25-3-5-29(61)43(41)73-45(47)27(9-11-49(47,71)31(59)17-25)57-39(69)23-55-37(67)21-53-35(65)19-51-33(63)7-8-34(64)52-20-36(66)54-22-38(68)56-24-40(70)58-28-10-12-50(72)32-18-26-4-6-30(62)44-42(26)48(50,46(28)74-44)14-16-60(32)2/h3-6,27-28,31-32,45-46,61-62,71-72H,7-24H2,1-2H3,(H,51,63)(H,52,64)(H,53,65)(H,54,66)(H,55,67)(H,56,68)(H,57,69)(H,58,70)/t27-,28-,31?,32?,45-,46-,47?,48?,49+,50+/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021494
(1N-[10,17-dihydroxy-4-methyl-(13R,14R,17S)-12-oxa-...)Show SMILES [H][C@@]12Oc3c4c(C[C@H]5N(C)CC[C@@]14[C@@]5(O)CC[C@H]2NC(C)=O)ccc3O |THB:9:8:13:4.5.6| Show InChI InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14?,17+,18?,19-/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 4.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig)) | BDBM50021503
(1N-[10,17-dihydroxy-4-methyl-(13R,14S,17S)-12-oxa-...)Show SMILES [H][C@@]12Oc3c4c(C[C@@]5([H])N(C)CC[C@@]14[C@@]5(O)CC[C@@H]2NC(C)=O)ccc3O |r,THB:10:9:14:4.5.6| Show InChI InChI=1S/C19H24N2O4/c1-10(22)20-12-5-6-19(24)14-9-11-3-4-13(23)16-15(11)18(19,17(12)25-16)7-8-21(14)2/h3-4,12,14,17,23-24H,5-9H2,1-2H3,(H,20,22)/t12-,14+,17-,18-,19+/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 6.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description
Displacement of [3H]-DADLE from Opioid receptor kappa 1 in guinea pig brain membrane |
J Med Chem 29: 1855-61 (1986)
BindingDB Entry DOI: 10.7270/Q21Z43DQ |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50318385
(2-(4-{[(2-{[(3-{[1-(5-{[(1R)-1-{[(4R,7S,10S,13R,16...)Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CCCCCn2cc(COc3cccc(c3)C(=O)NS(=O)(=O)CCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)nn2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r| Show InChI InChI=1S/C83H115N19O23S3/c1-52(104)67(48-103)91-82(121)69-51-127-126-50-68(81(120)89-65(39-55-22-24-59(106)25-23-55)79(118)90-66(41-57-42-86-62-19-9-8-18-61(57)62)80(119)88-63(20-10-11-26-84)77(116)94-75(53(2)105)83(122)93-69)92-78(117)64(38-54-14-5-3-6-15-54)87-70(107)21-7-4-12-28-102-43-58(95-97-102)49-125-60-17-13-16-56(40-60)76(115)96-128(123,124)37-27-85-71(108)44-98-29-31-99(45-72(109)110)33-35-101(47-74(113)114)36-34-100(32-30-98)46-73(111)112/h3,5-6,8-9,13-19,22-25,40,42-43,52-53,63-69,75,86,103-106H,4,7,10-12,20-21,26-39,41,44-51,84H2,1-2H3,(H,85,108)(H,87,107)(H,88,119)(H,89,120)(H,90,118)(H,91,121)(H,92,117)(H,93,122)(H,94,116)(H,96,115)(H,109,110)(H,111,112)(H,113,114)/t52-,53-,63+,64-,65+,66-,67-,68+,69+,75+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.32 | n/a | n/a | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Displacement of [111In-DOTA0,Tyr3]octreotide from SSTR2 receptor in rat AR42J cells |
J Med Chem 53: 3944-53 (2010)
Article DOI: 10.1021/jm100246m
BindingDB Entry DOI: 10.7270/Q2PG1RX7 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50318388
((4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2R,3...)Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CCCCCn2cc(CO)nn2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r| Show InChI InChI=1S/C58H79N13O13S2/c1-34(74)47(31-73)65-57(83)49-33-86-85-32-48(66-53(79)44(25-36-13-5-3-6-14-36)61-50(77)18-7-4-12-24-71-29-39(30-72)69-70-71)56(82)63-45(26-37-19-21-40(76)22-20-37)54(80)64-46(27-38-28-60-42-16-9-8-15-41(38)42)55(81)62-43(17-10-11-23-59)52(78)68-51(35(2)75)58(84)67-49/h3,5-6,8-9,13-16,19-22,28-29,34-35,43-49,51,60,72-76H,4,7,10-12,17-18,23-27,30-33,59H2,1-2H3,(H,61,77)(H,62,81)(H,63,82)(H,64,80)(H,65,83)(H,66,79)(H,67,84)(H,68,78)/t34-,35-,43+,44-,45+,46-,47-,48+,49+,51+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.45 | n/a | n/a | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Displacement of [111In-DOTA0,Tyr3]octreotide from SSTR2 receptor in rat AR42J cells |
J Med Chem 53: 3944-53 (2010)
Article DOI: 10.1021/jm100246m
BindingDB Entry DOI: 10.7270/Q2PG1RX7 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50318386
(2-[7-({[2-({[3,5-bis({[1-(5-{[(1R)-1-{[(4R,7S,10S,...)Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CCCCCn2cc(COc3cc(OCc4cn(CCCCCC(=O)N[C@H](Cc5ccccc5)C(=O)N[C@H]5CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc6c[nH]c7ccccc67)NC(=O)[C@H](Cc6ccc(O)cc6)NC5=O)[C@@H](C)O)C(=O)N[C@H](CO)[C@@H](C)O)nn4)cc(c3)C(=O)NS(=O)(=O)CCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)nn2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r| Show InChI InChI=1S/C141H192N32O36S5/c1-84(176)113(76-174)155-138(202)117-82-212-210-80-115(136(200)151-109(61-90-37-41-97(180)42-38-90)132(196)153-111(65-93-68-145-103-31-17-15-29-101(93)103)134(198)149-105(33-19-21-45-142)128(192)161-125(86(3)178)140(204)159-117)157-130(194)107(59-88-25-9-5-10-26-88)147-119(182)35-13-7-23-48-172-70-95(163-166-172)78-208-99-63-92(127(191)165-214(206,207)58-47-144-121(184)72-168-50-52-169(73-122(185)186)54-56-171(75-124(189)190)57-55-170(53-51-168)74-123(187)188)64-100(67-99)209-79-96-71-173(167-164-96)49-24-8-14-36-120(183)148-108(60-89-27-11-6-12-28-89)131(195)158-116-81-211-213-83-118(139(203)156-114(77-175)85(2)177)160-141(205)126(87(4)179)162-129(193)106(34-20-22-46-143)150-135(199)112(66-94-69-146-104-32-18-16-30-102(94)104)154-133(197)110(152-137(116)201)62-91-39-43-98(181)44-40-91/h5-6,9-12,15-18,25-32,37-44,63-64,67-71,84-87,105-118,125-126,145-146,174-181H,7-8,13-14,19-24,33-36,45-62,65-66,72-83,142-143H2,1-4H3,(H,144,184)(H,147,182)(H,148,183)(H,149,198)(H,150,199)(H,151,200)(H,152,201)(H,153,196)(H,154,197)(H,155,202)(H,156,203)(H,157,194)(H,158,195)(H,159,204)(H,160,205)(H,161,192)(H,162,193)(H,165,191)(H,185,186)(H,187,188)(H,189,190)/t84-,85-,86-,87-,105+,106+,107-,108-,109+,110+,111-,112-,113-,114-,115+,116+,117+,118+,125+,126+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.45 | n/a | n/a | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Displacement of [111In-DOTA0,Tyr3]octreotide from SSTR2 receptor in rat AR42J cells |
J Med Chem 53: 3944-53 (2010)
Article DOI: 10.1021/jm100246m
BindingDB Entry DOI: 10.7270/Q2PG1RX7 |
More data for this
Ligand-Target Pair | |
Somatostatin receptor type 2
(RAT) | BDBM50318387
(CHEMBL1099306)Show SMILES C[C@@H](O)[C@@H](CO)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)CCCCCn2cc(COc3cc(OCc4cn(CCCCCC(=O)N[C@H](Cc5ccccc5)C(=O)N[C@H]5CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc6c[nH]c7ccccc67)NC(=O)[C@H](Cc6ccc(O)cc6)NC5=O)[C@@H](C)O)C(=O)N[C@H](CO)[C@@H](C)O)nn4)cc(c3)C(=O)NCCOc3cc(OCCNC(=O)c4cc(OCc5cn(CCCCCC(=O)N[C@H](Cc6ccccc6)C(=O)N[C@H]6CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc7c[nH]c8ccccc78)NC(=O)[C@H](Cc7ccc(O)cc7)NC6=O)[C@@H](C)O)C(=O)N[C@H](CO)[C@@H](C)O)nn5)cc(OCc5cn(CCCCCC(=O)N[C@H](Cc6ccccc6)C(=O)N[C@H]6CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc7c[nH]c8ccccc78)NC(=O)[C@H](Cc7ccc(O)cc7)NC6=O)[C@@H](C)O)C(=O)N[C@H](CO)[C@@H](C)O)nn5)c4)cc(c3)C(=O)NS(=O)(=O)CCNC(=O)CN3CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC3)nn2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@H](Cc2c[nH]c3ccccc23)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 |r| Show InChI InChI=1S/C275H364N60O66S9/c1-160(340)221(144-336)303-268(386)229-156-406-402-152-225(264(382)295-213(115-172-73-81-187(348)82-74-172)256(374)299-217(125-179-132-283-201-61-33-29-57-197(179)201)260(378)291-205(65-37-41-89-276)248(366)315-241(164(5)344)272(390)311-229)307-252(370)209(111-168-49-17-9-18-50-168)287-233(352)69-25-13-45-96-332-136-183(319-324-332)148-398-193-119-176(120-194(130-193)399-149-184-137-333(325-320-184)97-46-14-26-70-234(353)288-210(112-169-51-19-10-20-52-169)253(371)308-226-153-403-407-157-230(269(387)304-222(145-337)161(2)341)312-273(391)242(165(6)345)316-249(367)206(66-38-42-90-277)292-261(379)218(126-180-133-284-202-62-34-30-58-198(180)202)300-257(375)214(296-265(226)383)116-173-75-83-188(349)84-76-173)245(363)281-93-108-396-191-123-178(247(365)323-410(394,395)110-95-280-237(356)140-328-100-102-329(141-238(357)358)104-106-331(143-240(361)362)107-105-330(103-101-328)142-239(359)360)124-192(129-191)397-109-94-282-246(364)177-121-195(400-150-185-138-334(326-321-185)98-47-15-27-71-235(354)289-211(113-170-53-21-11-22-54-170)254(372)309-227-154-404-408-158-231(270(388)305-223(146-338)162(3)342)313-274(392)243(166(7)346)317-250(368)207(67-39-43-91-278)293-262(380)219(127-181-134-285-203-63-35-31-59-199(181)203)301-258(376)215(297-266(227)384)117-174-77-85-189(350)86-78-174)131-196(122-177)401-151-186-139-335(327-322-186)99-48-16-28-72-236(355)290-212(114-171-55-23-12-24-56-171)255(373)310-228-155-405-409-159-232(271(389)306-224(147-339)163(4)343)314-275(393)244(167(8)347)318-251(369)208(68-40-44-92-279)294-263(381)220(128-182-135-286-204-64-36-32-60-200(182)204)302-259(377)216(298-267(228)385)118-175-79-87-190(351)88-80-175/h9-12,17-24,29-36,49-64,73-88,119-124,129-139,160-167,205-232,241-244,283-286,336-351H,13-16,25-28,37-48,65-72,89-118,125-128,140-159,276-279H2,1-8H3,(H,280,356)(H,281,363)(H,282,364)(H,287,352)(H,288,353)(H,289,354)(H,290,355)(H,291,378)(H,292,379)(H,293,380)(H,294,381)(H,295,382)(H,296,383)(H,297,384)(H,298,385)(H,299,374)(H,300,375)(H,301,376)(H,302,377)(H,303,386)(H,304,387)(H,305,388)(H,306,389)(H,307,370)(H,308,371)(H,309,372)(H,310,373)(H,311,390)(H,312,391)(H,313,392)(H,314,393)(H,315,366)(H,316,367)(H,317,368)(H,318,369)(H,323,365)(H,357,358)(H,359,360)(H,361,362)/t160-,161-,162-,163-,164-,165-,166-,167-,205+,206+,207+,208+,209-,210-,211-,212-,213+,214+,215+,216+,217-,218-,219-,220-,221-,222-,223-,224-,225+,226+,227+,228+,229+,230+,231+,232+,241+,242+,243+,244+/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Utrecht University
Curated by ChEMBL
| Assay Description
Displacement of [111In-DOTA0,Tyr3]octreotide from SSTR2 receptor in rat AR42J cells |
J Med Chem 53: 3944-53 (2010)
Article DOI: 10.1021/jm100246m
BindingDB Entry DOI: 10.7270/Q2PG1RX7 |
More data for this
Ligand-Target Pair | |
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