Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154254 (CHEMBL3775705) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p... | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154253 (CHEMBL3775377) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p... | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154252 (CHEMBL3774934) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Competitive inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by Lineweaver-Burk p... | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-7 (Homo sapiens (Human)) | BDBM50355086 (CHEMBL1834753) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.22E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 7 using Abz-KLYSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355088 (CHEMBL1834754) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355086 (CHEMBL1834753) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.44E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-7 (Homo sapiens (Human)) | BDBM50355088 (CHEMBL1834754) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.72E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 7 using Abz-KLYSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355087 (CHEMBL1833982) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-7 (Homo sapiens (Human)) | BDBM50355087 (CHEMBL1833982) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 7 using Abz-KLYSSKQ-EDDnp as substrate by Lineweaver-Burk plot analysis | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154254 (CHEMBL3775705) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysis | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154253 (CHEMBL3775377) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 115 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysis | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50154252 (CHEMBL3774934) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 122 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal Fluminense Curated by ChEMBL | Assay Description Inhibition of human KLK5 using Abz-KLRSSKQ-EDDnp as substrate preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysis | Eur J Med Chem 112: 39-47 (2016) Article DOI: 10.1016/j.ejmech.2016.01.060 BindingDB Entry DOI: 10.7270/Q2445PBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355088 (CHEMBL1834754) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.37E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by spectrofluorimetric assay | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355086 (CHEMBL1834753) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.29E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by spectrofluorimetric assay | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-7 (Homo sapiens (Human)) | BDBM50355086 (CHEMBL1834753) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 7 using Abz-KLYSSKQ-EDDnp as substrate by spectrofluorimetric assay | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-7 (Homo sapiens (Human)) | BDBM50355088 (CHEMBL1834754) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 7 using Abz-KLYSSKQ-EDDnp as substrate by spectrofluorimetric assay | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-7 (Homo sapiens (Human)) | BDBM50355087 (CHEMBL1833982) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.66E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 7 using Abz-KLYSSKQ-EDDnp as substrate by spectrofluorimetric assay | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kallikrein-5 [D153N] (Homo sapiens (Human)) | BDBM50355087 (CHEMBL1833982) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.67E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Tri£ngulo Mineiro Curated by ChEMBL | Assay Description Inhibition of human kallikrein 5 using Abz-KLRSSKQ-EDDnp as substrate by spectrofluorimetric assay | Bioorg Med Chem Lett 21: 6112-5 (2011) Article DOI: 10.1016/j.bmcl.2011.08.044 BindingDB Entry DOI: 10.7270/Q24M94ZP | |||||||||||
More data for this Ligand-Target Pair |