Found 19 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Steroidogenic factor 1
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
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| PCBioAssay
| n/a | n/a | 2.82E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2PR7TCX |
More data for this Ligand-Target Pair | |
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
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Similars
| PCBioAssay
| n/a | n/a | 2.95E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2TH8K3N |
More data for this Ligand-Target Pair | |
Steroidogenic factor 1
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q2319T8T |
More data for this Ligand-Target Pair | |
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | 1.71E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center
Curated by PubChem BioAssay
| Assay Description Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ... |
PubChem Bioassay (2007)
BindingDB Entry DOI: 10.7270/Q26Q1VNZ |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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| Article PubMed
| n/a | n/a | 2.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Displacement of [125I]-CCL3 from human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr after 3 hrs |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
Intestinal-type alkaline phosphatase 1
(Rattus norvegicus (Rat)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q25Q4TJ1 |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.16E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun... |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 5
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.90E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Allosteric modulation at human CCR5 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as [3H]IP3 turnover by liquid scintillation coun... |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
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Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.40E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun... |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 8
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.01E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 8
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Allosteric modulation at human CCR8 transfected in COS7 cells assessed as [3H]IP3 turnover by liquid scintillation counting analysis |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
C-C chemokine receptor type 1
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.31E+4 | n/a | n/a | n/a | n/a |
University of Copenhagen
Curated by ChEMBL
| Assay Description Allosteric modulation at human CCR1 transfected in COS7 cells coexpressing chimeric Gqi4myr assessed as {3H]IP3 turnover by liquid scintillation coun... |
J Med Chem 55: 8164-77 (2012)
Article DOI: 10.1021/jm301121j BindingDB Entry DOI: 10.7270/Q2Q81F7S |
More data for this Ligand-Target Pair | |
Intestinal-type alkaline phosphatase
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 2.53E+4 | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2CF9NKD |
More data for this Ligand-Target Pair | |
Alkaline phosphatase, tissue-nonspecific isozyme
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 2.75E+4 | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q24Q7SF3 |
More data for this Ligand-Target Pair | |
Intestinal-type alkaline phosphatase
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 1.68E+4 | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q2ST7N9K |
More data for this Ligand-Target Pair | |
ATP-dependent molecular chaperone HSP82
(Candida albicans) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
UniProtKB/TrEMBL
B.MOAD GoogleScholar AffyNet
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MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 521 | n/a | n/a | n/a | n/a |
Broad Institute
Curated by PubChem BioAssay
| Assay Description Broad Institute: Reversing Antifungal Drug Resistance Project ID: 2037 Keywords: Candida albicans, drug resistance, Fluconazole, Hsp90, Calcineurin, ... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q26M358G |
More data for this Ligand-Target Pair | |
Vacuolar aminopeptidase 1
(Saccharomyces cerevisiae) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a |
NMMLSC
Curated by PubChem BioAssay
| Assay Description University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q21R6P02 |
More data for this Ligand-Target Pair | |
Alkaline phosphatase, germ cell type
(Homo sapiens (Human)) | BDBM38924
(2,6-bis(2-pyridinyl)pyridine | 2,6-bis(2-pyridyl)p...)Show InChI InChI=1S/C15H11N3/c1-3-10-16-12(6-1)14-8-5-9-15(18-14)13-7-2-4-11-17-13/h1-11H | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE PC cid PC sid UniChem
Patents
Similars
| PCBioAssay
| n/a | n/a | n/a | n/a | 2.71E+4 | n/a | n/a | n/a | n/a |
Burnham Center for Chemical Genomics
Curated by PubChem BioAssay
| Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C... |
PubChem Bioassay (2010)
BindingDB Entry DOI: 10.7270/Q20Z71R6 |
More data for this Ligand-Target Pair | |