Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Muscarinic acetylcholine receptor M2
(RAT) | BDBM50453900
(CHEMBL3084866)Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccc(cc1)C(C)(C)C)N2C |TLB:9:7:27:3.2| Show InChI InChI=1S/C25H33NO/c1-25(2,3)20-12-10-19(11-13-20)24(18-8-6-5-7-9-18)27-23-16-21-14-15-22(17-23)26(21)4/h5-13,21-24H,14-17H2,1-4H3/t21-,22+,23+,24? | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description
Affinity for rat M1 acetylcholine receptor using [3H]-AF DX 384 displacement. |
J Med Chem 38: 3933-40 (1995)
BindingDB Entry DOI: 10.7270/Q20V8DF2 |
More data for this
Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(RAT) | BDBM50453900
(CHEMBL3084866)Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccc(cc1)C(C)(C)C)N2C |TLB:9:7:27:3.2| Show InChI InChI=1S/C25H33NO/c1-25(2,3)20-12-10-19(11-13-20)24(18-8-6-5-7-9-18)27-23-16-21-14-15-22(17-23)26(21)4/h5-13,21-24H,14-17H2,1-4H3/t21-,22+,23+,24? | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 148 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description
Affinity for rat M1 acetylcholine receptor using [3H]pirenzepine displacement. |
J Med Chem 38: 3933-40 (1995)
BindingDB Entry DOI: 10.7270/Q20V8DF2 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50453900
(CHEMBL3084866)Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccc(cc1)C(C)(C)C)N2C |TLB:9:7:27:3.2| Show InChI InChI=1S/C25H33NO/c1-25(2,3)20-12-10-19(11-13-20)24(18-8-6-5-7-9-18)27-23-16-21-14-15-22(17-23)26(21)4/h5-13,21-24H,14-17H2,1-4H3/t21-,22+,23+,24? | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| 1.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description
Affinity for rat dopamine transporter using [3H]WIN-35428 displacement. |
J Med Chem 38: 3933-40 (1995)
BindingDB Entry DOI: 10.7270/Q20V8DF2 |
More data for this
Ligand-Target Pair | |
Sodium-dependent dopamine transporter
(Rattus norvegicus (rat)) | BDBM50453900
(CHEMBL3084866)Show SMILES [H][C@]12CC[C@]([H])(C[C@@H](C1)OC(c1ccccc1)c1ccc(cc1)C(C)(C)C)N2C |TLB:9:7:27:3.2| Show InChI InChI=1S/C25H33NO/c1-25(2,3)20-12-10-19(11-13-20)24(18-8-6-5-7-9-18)27-23-16-21-14-15-22(17-23)26(21)4/h5-13,21-24H,14-17H2,1-4H3/t21-,22+,23+,24? | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.46E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
National Institutes of Health
Curated by ChEMBL
| Assay Description
Inhibition of [3H]dopamine uptake in rat caudate putamen. |
J Med Chem 38: 3933-40 (1995)
BindingDB Entry DOI: 10.7270/Q20V8DF2 |
More data for this
Ligand-Target Pair | |