Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 339.3 BDBM24211

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24211 (4-{2-[4-(1H-1,3-benzodiazol-2-yloxy)phenoxy]ethyl}...) Show SMILES C(CN1CCOCC1)Oc1ccc(Oc2nc3ccccc3[nH]2)cc1 Show InChI InChI=1S/C19H21N3O3/c1-2-4-18-17(3-1)20-19(21-18)25-16-7-5-15(6-8-16)24-14-11-22-9-12-23-13-10-22/h1-8H,9-14H2,(H,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	7.4	22
Johnson & Johnson Pharmaceutical					Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair