Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 368.4 BDBM24241

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24241 (2-{4-[3-(piperidin-1-yl)propoxy]phenoxy}-1,3-benzo...) Show SMILES C(COc1ccc(Oc2nc3ccccc3s2)cc1)CN1CCCCC1 Show InChI InChI=1S/C21H24N2O2S/c1-4-13-23(14-5-1)15-6-16-24-17-9-11-18(12-10-17)25-21-22-19-7-2-3-8-20(19)26-21/h2-3,7-12H,1,4-6,13-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	25
Johnson & Johnson Pharmaceutical					Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair