Found 4 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Neuropeptide Y receptor type 1
(Homo sapiens (Human)) | BDBM50312042
((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...)Show SMILES C(Cc1ccc(cc1)N=C1N[C@@H](CCS1)c1ccccc1)Nc1nc2ccccc2s1 |r,w:8.8| Show InChI InChI=1S/C25H24N4S2/c1-2-6-19(7-3-1)21-15-17-30-25(28-21)27-20-12-10-18(11-13-20)14-16-26-24-29-22-8-4-5-9-23(22)31-24/h1-13,21H,14-17H2,(H,26,29)(H,27,28)/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]pig PPY from human NPY1 receptor expressed in CHOK1 cells by scintillation counting |
Bioorg Med Chem Lett 19: 6801-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 5
(Homo sapiens (Human)) | BDBM50312042
((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...)Show SMILES C(Cc1ccc(cc1)N=C1N[C@@H](CCS1)c1ccccc1)Nc1nc2ccccc2s1 |r,w:8.8| Show InChI InChI=1S/C25H24N4S2/c1-2-6-19(7-3-1)21-15-17-30-25(28-21)27-20-12-10-18(11-13-20)14-16-26-24-29-22-8-4-5-9-23(22)31-24/h1-13,21H,14-17H2,(H,26,29)(H,27,28)/t21-/m0/s1 | KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.98E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]pig PPY from human NPY5 receptor expressed in CHOK1 cells by scintillation counting |
Bioorg Med Chem Lett 19: 6801-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 4
(Homo sapiens (Human)) | BDBM50312042
((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...)Show SMILES C(Cc1ccc(cc1)N=C1N[C@@H](CCS1)c1ccccc1)Nc1nc2ccccc2s1 |r,w:8.8| Show InChI InChI=1S/C25H24N4S2/c1-2-6-19(7-3-1)21-15-17-30-25(28-21)27-20-12-10-18(11-13-20)14-16-26-24-29-22-8-4-5-9-23(22)31-24/h1-13,21H,14-17H2,(H,26,29)(H,27,28)/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]human PP from human NPY4 receptor expressed in CHOK1 cells by scintillation counting |
Bioorg Med Chem Lett 19: 6801-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z |
More data for this Ligand-Target Pair | |
Neuropeptide Y receptor type 2
(Homo sapiens (Human)) | BDBM50312042
((S)-N-(4-(4-phenyl-5,6-dihydro-4H-1,3-thiazin-2-yl...)Show SMILES C(Cc1ccc(cc1)N=C1N[C@@H](CCS1)c1ccccc1)Nc1nc2ccccc2s1 |r,w:8.8| Show InChI InChI=1S/C25H24N4S2/c1-2-6-19(7-3-1)21-15-17-30-25(28-21)27-20-12-10-18(11-13-20)14-16-26-24-29-22-8-4-5-9-23(22)31-24/h1-13,21H,14-17H2,(H,26,29)(H,27,28)/t21-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Schering Plough Research Institute
Curated by ChEMBL
| Assay Description Displacement of [125I]pig PPY from human NPY2 receptor expressed in CHOK1 cells by scintillation counting |
Bioorg Med Chem Lett 19: 6801-5 (2009)
Article DOI: 10.1016/j.bmcl.2009.09.048 BindingDB Entry DOI: 10.7270/Q2XP753Z |
More data for this Ligand-Target Pair | |