Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Leukotriene A-4 hydrolase
(Cavia porcellus) | BDBM50266315
((2R)-3-((4-cyclohexylphenyl)(phenyl)methylthio)-2-...)Show SMILES C[C@H](CS)C(=O)N[C@@H](CSC(c1ccccc1)c1ccc(cc1)C1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C26H33NO3S2/c1-18(16-31)25(28)27-23(26(29)30)17-32-24(21-10-6-3-7-11-21)22-14-12-20(13-15-22)19-8-4-2-5-9-19/h3,6-7,10-15,18-19,23-24,31H,2,4-5,8-9,16-17H2,1H3,(H,27,28)(H,29,30)/t18-,23+,24?/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this Ligand-Target Pair | |
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50266315
((2R)-3-((4-cyclohexylphenyl)(phenyl)methylthio)-2-...)Show SMILES C[C@H](CS)C(=O)N[C@@H](CSC(c1ccccc1)c1ccc(cc1)C1CCCCC1)C(O)=O |r| Show InChI InChI=1S/C26H33NO3S2/c1-18(16-31)25(28)27-23(26(29)30)17-32-24(21-10-6-3-7-11-21)22-14-12-20(13-15-22)19-8-4-2-5-9-19/h3,6-7,10-15,18-19,23-24,31H,2,4-5,8-9,16-17H2,1H3,(H,27,28)(H,29,30)/t18-,23+,24?/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLC |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042 BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this Ligand-Target Pair | |