Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Angiotensin-converting enzyme
(Homo sapiens (Human)) | BDBM50266174
((R)-3-(biphenyl-4-ylmethylthio)-2-((S)-3-mercapto-...)Show SMILES C[C@H](CS)C(=O)N[C@@H](CSCc1ccc(cc1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO3S2/c1-14(11-25)19(22)21-18(20(23)24)13-26-12-15-7-9-17(10-8-15)16-5-3-2-4-6-16/h2-10,14,18,25H,11-13H2,1H3,(H,21,22)(H,23,24)/t14-,18+/m1/s1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of angiotensin-converting enzyme (unknown origin) in whole blood by HPLC |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042
BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this
Ligand-Target Pair | |
Leukotriene A-4 hydrolase
(Cavia porcellus) | BDBM50266174
((R)-3-(biphenyl-4-ylmethylthio)-2-((S)-3-mercapto-...)Show SMILES C[C@H](CS)C(=O)N[C@@H](CSCc1ccc(cc1)-c1ccccc1)C(O)=O |r| Show InChI InChI=1S/C20H23NO3S2/c1-14(11-25)19(22)21-18(20(23)24)13-26-12-15-7-9-17(10-8-15)16-5-3-2-4-6-16/h2-10,14,18,25H,11-13H2,1H3,(H,21,22)(H,23,24)/t14-,18+/m1/s1 | PDB
MMDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Santen Pharmaceutical Co., Ltd
Curated by ChEMBL
| Assay Description
Inhibition of LTA4 hydrolase in guinea pig lung assessed as inhibition of LTB4 production |
Bioorg Med Chem Lett 19: 442-6 (2008)
Article DOI: 10.1016/j.bmcl.2008.11.042
BindingDB Entry DOI: 10.7270/Q20K28FC |
More data for this
Ligand-Target Pair | |