Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Melanocortin receptor 5
(Mus musculus (Mouse)) | BDBM50537083
(CHEMBL4550976)Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C32H42IN9O6/c1-18(43)39-23(7-4-14-38-32(36)37)29(46)40-24(12-13-27(34)44)30(47)41-25(15-19-8-10-22(33)11-9-19)31(48)42-17-21-6-3-2-5-20(21)16-26(42)28(35)45/h2-3,5-6,8-11,23-26H,4,7,12-17H2,1H3,(H2,34,44)(H2,35,45)(H,39,43)(H,40,46)(H,41,47)(H4,36,37,38)/t23-,24-,25+,26+/m0/s1 | UniProtKB/SwissProt
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.60 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Full agonist activity at mouse MC5R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cA... |
J Med Chem 62: 2738-2749 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00053
BindingDB Entry DOI: 10.7270/Q2HT2SWG |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 4
(Mus musculus) | BDBM50537083
(CHEMBL4550976)Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C32H42IN9O6/c1-18(43)39-23(7-4-14-38-32(36)37)29(46)40-24(12-13-27(34)44)30(47)41-25(15-19-8-10-22(33)11-9-19)31(48)42-17-21-6-3-2-5-20(21)16-26(42)28(35)45/h2-3,5-6,8-11,23-26H,4,7,12-17H2,1H3,(H2,34,44)(H2,35,45)(H,39,43)(H,40,46)(H,41,47)(H4,36,37,38)/t23-,24-,25+,26+/m0/s1 | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Agonist activity at mouse MC4R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cAMP as... |
J Med Chem 62: 2738-2749 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00053
BindingDB Entry DOI: 10.7270/Q2HT2SWG |
More data for this
Ligand-Target Pair | |
Melanocortin receptor 3
(Mus musculus) | BDBM50537083
(CHEMBL4550976)Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C32H42IN9O6/c1-18(43)39-23(7-4-14-38-32(36)37)29(46)40-24(12-13-27(34)44)30(47)41-25(15-19-8-10-22(33)11-9-19)31(48)42-17-21-6-3-2-5-20(21)16-26(42)28(35)45/h2-3,5-6,8-11,23-26H,4,7,12-17H2,1H3,(H2,34,44)(H2,35,45)(H,39,43)(H,40,46)(H,41,47)(H4,36,37,38)/t23-,24-,25+,26+/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 15 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Agonist activity at mouse MC3R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cAMP as... |
J Med Chem 62: 2738-2749 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00053
BindingDB Entry DOI: 10.7270/Q2HT2SWG |
More data for this
Ligand-Target Pair | |
Melanocyte-stimulating hormone receptor
(Mus musculus) | BDBM50537083
(CHEMBL4550976)Show SMILES CC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccc(I)cc1)C(=O)N1Cc2ccccc2C[C@@H]1C(N)=O |r| Show InChI InChI=1S/C32H42IN9O6/c1-18(43)39-23(7-4-14-38-32(36)37)29(46)40-24(12-13-27(34)44)30(47)41-25(15-19-8-10-22(33)11-9-19)31(48)42-17-21-6-3-2-5-20(21)16-26(42)28(35)45/h2-3,5-6,8-11,23-26H,4,7,12-17H2,1H3,(H2,34,44)(H2,35,45)(H,39,43)(H,40,46)(H,41,47)(H4,36,37,38)/t23-,24-,25+,26+/m0/s1 | KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | n/a | n/a | 10 | n/a | n/a | n/a | n/a |
University of Minnesota
Curated by ChEMBL
| Assay Description
Full agonist activity at mouse MC1R expressed in HEK293 cells co-expressing CRE/beta-galactosidase reporter gene after 6 hrs by beta-galactosidase cA... |
J Med Chem 62: 2738-2749 (2019)
Article DOI: 10.1021/acs.jmedchem.9b00053
BindingDB Entry DOI: 10.7270/Q2HT2SWG |
More data for this
Ligand-Target Pair | |