Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 499.5 BDBM367491

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitotic checkpoint serine/threonine-protein kinase BUB1 (Homo sapiens (Human))	BDBM367491 (N-4-[(6RS)-6-Methyl-6-(2-oxa-6-azaspiro[3.3]hept-6...) Show SMILES CC(=O)Nc1cc(ccn1)-c1[nH]c2CC(C)(CC(=O)c2c1Nc1ccccc1)C(=O)N1CC2(COC2)C1 |w:14.31,14.15| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	932	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer					Assay Description Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...				J Med Chem 51: 1377-84 (2008) BindingDB Entry DOI: 10.7270/Q2QN6931
					More data for this Ligand-Target Pair