Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 439.5 BDBM24237

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A-4 hydrolase (Homo sapiens (Human))	BDBM24237 (Benzthiazole compound, 33o | [(1-{[4-(1,3-benzothi...) Show SMILES CC(=O)OCC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C23H25N3O4S/c1-16(27)29-15-22(28)24-18-10-12-26(13-11-18)14-17-6-8-19(9-7-17)30-23-25-20-4-2-3-5-21(20)31-23/h2-9,18H,10-15H2,1H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	25
Johnson & Johnson Pharmaceutical					Assay Description Recombinant human LTA4H was incubated with various concentrations of test compound for 10 min at room temperature in assay buffer, and the substrate,...				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM24237 (Benzthiazole compound, 33o | [(1-{[4-(1,3-benzothi...) Show SMILES CC(=O)OCC(=O)NC1CCN(Cc2ccc(Oc3nc4ccccc4s3)cc2)CC1 Show InChI InChI=1S/C23H25N3O4S/c1-16(27)29-15-22(28)24-18-10-12-26(13-11-18)14-17-6-8-19(9-7-17)30-23-25-20-4-2-3-5-21(20)31-23/h2-9,18H,10-15H2,1H3,(H,24,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical					Assay Description Compounds were assessed for their ability to displace [3H]astemizole using membranes from HEK-293 cells expressing the hERG K+ channel.				J Med Chem 51: 4150-69 (2008) Article DOI: 10.1021/jm701575k BindingDB Entry DOI: 10.7270/Q2GB22CX
					More data for this Ligand-Target Pair