Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 512.6 BDBM435264

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 2 (Homo sapiens (Human))	BDBM435264 (N-(tert-butyl)-5-(5- (hydroxymethyl)pyridin-3-yl)-...) Show SMILES CC(C)(C)NC(=O)N1CCc2c(C1)c(CNC(=O)C1C[C@H]1c1ccccc1)ccc2-c1cncc(CO)c1 |r| Show InChI InChI=1S/C31H36N4O3/c1-31(2,3)34-30(38)35-12-11-25-24(23-13-20(19-36)15-32-16-23)10-9-22(28(25)18-35)17-33-29(37)27-14-26(27)21-7-5-4-6-8-21/h4-10,13,15-16,26-27,36H,11-12,14,17-19H2,1-3H3,(H,33,37)(H,34,38)/t26-,27?/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	992	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...				US Patent US10568876 (2020) BindingDB Entry DOI: 10.7270/Q22B91FB
					More data for this Ligand-Target Pair