Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 308.4 BDBM50051485

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50051485 ((S)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.2...) Show SMILES CC(C)(C)OC(=O)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1 |wU:14.16,(10.06,-15.21,;11.39,-15.99,;12.88,-16.39,;11.39,-17.53,;12.72,-15.22,;12.72,-13.68,;14.05,-12.91,;11.39,-12.91,;10.06,-13.67,;8.73,-12.91,;8.73,-11.37,;10.06,-10.59,;9.29,-11.92,;10.76,-11.51,;11.39,-11.37,;12.72,-10.6,;14.05,-11.37,;12.74,-9.06,;11.5,-8.15,;11.98,-6.68,;13.49,-6.67,;13.98,-8.15,)| Show InChI InChI=1S/C17H28N2O3/c1-17(2,3)22-16(21)19-13-8-6-12(7-9-13)14(19)15(20)18-10-4-5-11-18/h12-14H,4-11H2,1-3H3/t12?,13?,14-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticum				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair