Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 248.3 BDBM50240829Purchase

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 20 hits in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.0631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Effect on pancreatic polypeptide-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Effect on peptide YY-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell mem...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Effect on neuropeptide Y-mediated displacement of 125I-pancreatic polypeptide from human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cell...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	443	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0398	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.398	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 1 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0398	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-fused human NY1 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 2 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0631	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-fused human NY2 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 5 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3.20	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-fused human NY5 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	845	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of peptide YY-induced ...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.501	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	398	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of neuropeptide Y-indu...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-tagged NY4 receptor expressed in HEK293 cells assessed as potentiation of pancreatic polypept...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human C-terminal eYFP-fused human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Gal...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair
Neuropeptide Y receptor type 4 (Homo sapiens (Human))	BDBM50240829 (CHEMBL3559801) Show SMILES CC(C)(C)c1ccc(OC2CCCCC2O)cc1 Show InChI InChI=1S/C16H24O2/c1-16(2,3)12-8-10-13(11-9-12)18-15-7-5-4-6-14(15)17/h8-11,14-15,17H,4-7H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.5	n/a	n/a	n/a	n/a
Leipzig University Curated by ChEMBL					Assay Description Positive allosteric modulation of human NY4 receptor expressed in African green monkey COS7 cells co-expressing delta6Galphaqi4-myr assessed as poten...				J Med Chem 60: 7605-7612 (2017) Article DOI: 10.1021/acs.jmedchem.7b00976 BindingDB Entry DOI: 10.7270/Q22B915R
					More data for this Ligand-Target Pair