Found 2 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Thromboxane-A synthase
(Rattus norvegicus) | BDBM50037748
(5-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...)Show SMILES CC(C)(CCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1)C(O)=O Show InChI InChI=1S/C25H29N3O3/c1-25(2,24(29)30)14-9-17-31-27-23(21-12-7-4-8-13-21)22(28-16-15-26-19-28)18-20-10-5-3-6-11-20/h3-8,10-13,15-16,19,22H,9,14,17-18H2,1-2H3,(H,29,30)/b27-23+ | Reactome pathway
KEGG
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 760 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia-Farmitalia Carlo Erba
Curated by ChEMBL
| Assay Description
In vitro inhibition of thromboxane-A2 synthase in rat whole blood during clotting at 37 degrees centigrade |
J Med Chem 37: 3588-604 (1994)
BindingDB Entry DOI: 10.7270/Q2C24VFD |
More data for this
Ligand-Target Pair | |
Thromboxane A2 receptor
(Homo sapiens (Human)) | BDBM50037748
(5-[2-Imidazol-1-yl-1,3-diphenyl-prop-(E)-ylideneam...)Show SMILES CC(C)(CCCO\N=C(\C(Cc1ccccc1)n1ccnc1)c1ccccc1)C(O)=O Show InChI InChI=1S/C25H29N3O3/c1-25(2,24(29)30)14-9-17-31-27-23(21-12-7-4-8-13-21)22(28-16-15-26-19-28)18-20-10-5-3-6-11-20/h3-8,10-13,15-16,19,22H,9,14,17-18H2,1-2H3,(H,29,30)/b27-23+ | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| PubMed
| n/a | n/a | 4.16E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia-Farmitalia Carlo Erba
Curated by ChEMBL
| Assay Description
In vitro thromboxane-A2 receptor binding affinity to displace by 50% [3H]-SQ 29548 binding from washed human platelets |
J Med Chem 37: 3588-604 (1994)
BindingDB Entry DOI: 10.7270/Q2C24VFD |
More data for this
Ligand-Target Pair | |