Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Muscarinic acetylcholine receptor M3
(Homo sapiens (Human)) | BDBM50129384
((R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]...)Show SMILES CC(C)(N)CC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-20(2,25)14-16-9-12-26(13-10-16)19(27)22(28,17-6-4-3-5-7-17)18-8-11-21(23,24)15-18/h3-7,16,18,28H,8-15,25H2,1-2H3/t18-,22+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against human muscarinic acetylcholine receptor M3 in transfected CHO cells |
Bioorg Med Chem Lett 13: 2167-72 (2003)
BindingDB Entry DOI: 10.7270/Q29G5M68 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M1
(Homo sapiens (Human)) | BDBM50129384
((R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]...)Show SMILES CC(C)(N)CC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-20(2,25)14-16-9-12-26(13-10-16)19(27)22(28,17-6-4-3-5-7-17)18-8-11-21(23,24)15-18/h3-7,16,18,28H,8-15,25H2,1-2H3/t18-,22+/m1/s1 | UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against human Muscarinic acetylcholine receptor M1 in transfected CHO cells |
Bioorg Med Chem Lett 13: 2167-72 (2003)
BindingDB Entry DOI: 10.7270/Q29G5M68 |
More data for this Ligand-Target Pair | |
Muscarinic acetylcholine receptor M2
(Homo sapiens (Human)) | BDBM50129384
((R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]...)Show SMILES CC(C)(N)CC1CCN(CC1)C(=O)[C@@](O)([C@@H]1CCC(F)(F)C1)c1ccccc1 Show InChI InChI=1S/C22H32F2N2O2/c1-20(2,25)14-16-9-12-26(13-10-16)19(27)22(28,17-6-4-3-5-7-17)18-8-11-21(23,24)15-18/h3-7,16,18,28H,8-15,25H2,1-2H3/t18-,22+/m1/s1 | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| PubMed
| 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Banyu Tsukuba Research Institute in collaboration with Merck Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity against human muscarinic acetylcholine receptor M2 in transfected CHO cells |
Bioorg Med Chem Lett 13: 2167-72 (2003)
BindingDB Entry DOI: 10.7270/Q29G5M68 |
More data for this Ligand-Target Pair | |