Found 11 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MCT4 may be stably expressed in MDA-MB-453 breast cancer cells that do not express native MCT1 or MCT4. MCT4 activity may be assessed by monitoring t... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
NCI-H358 lung adenocarcinoma cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this
Ligand-Target Pair | |
Malignant T-cell-amplified sequence 1
(Homo sapiens (human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this
Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345266
(2-[[1-[(2-Chlorophenyl)methyl]-5-(3- fluorophenyl...)Show SMILES CC(C)(OCc1cc(-c2cccc(F)c2)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C21H20ClFN2O3/c1-21(2,20(26)27)28-13-17-11-19(14-7-5-8-16(23)10-14)25(24-17)12-15-6-3-4-9-18(15)22/h3-11H,12-13H2,1-2H3,(H,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description
MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this
Ligand-Target Pair | |