Found 2 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM356888
(US10214492, Example 239)Show SMILES CC(C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1C#N)C(O)=O Show InChI InChI=1S/C24H23N3O4/c1-24(2,23(28)29)30-15-18-13-22(16-7-5-8-20(12-16)31-19-10-11-19)27(26-18)21-9-4-3-6-17(21)14-25/h3-9,12-13,19H,10-11,15H2,1-2H3,(H,28,29) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM356888
(US10214492, Example 239)Show SMILES CC(C)(OCc1cc(-c2cccc(OC3CC3)c2)n(n1)-c1ccccc1C#N)C(O)=O Show InChI InChI=1S/C24H23N3O4/c1-24(2,23(28)29)30-15-18-13-22(16-7-5-8-20(12-16)31-19-10-11-19)27(26-18)21-9-4-3-6-17(21)14-25/h3-9,12-13,19H,10-11,15H2,1-2H3,(H,28,29) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this Ligand-Target Pair | |