Found 8 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 4
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MDA-MB-231 breast cancer cells may be used to measure MCT4 activity in cells with high native levels of MCT4 and low levels of MCT1 and are known to ... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2862KNG |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2CR5ZGC |
More data for this Ligand-Target Pair | |
Malignant T-cell-amplified sequence 1
(Homo sapiens (human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10202350 (2019)
BindingDB Entry DOI: 10.7270/Q20K2BPB |
More data for this Ligand-Target Pair | |
Monocarboxylate transporter 1
(Homo sapiens (Human)) | BDBM345302
(2-([1-[(o-Chlorophenyl)methyl]-5-(m- cyanophenyl)...)Show SMILES CC(C)(OCc1cc(-c2cccc(c2)C#N)n(Cc2ccccc2Cl)n1)C(O)=O Show InChI InChI=1S/C22H20ClN3O3/c1-22(2,21(27)28)29-14-18-11-20(16-8-5-6-15(10-16)12-24)26(25-18)13-17-7-3-4-9-19(17)23/h3-11H,13-14H2,1-2H3,(H,27,28) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| US Patent
| n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Vettore, LLC
US Patent
| Assay Description MCT1 activity may be measured using BT-20 breast cancer cells that express high native levels of MCT1, but do not express MCT4 and are known to those... |
US Patent US10214492 (2019)
BindingDB Entry DOI: 10.7270/Q2Q81GC0 |
More data for this Ligand-Target Pair | |