Found 3 hits in this display Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Peroxisome proliferator-activated receptor delta
(Homo sapiens (Human)) | BDBM50312420
(2-(4-((4-(4-(N-Isopropyl-N-methyl)benzamide)-5-(4-...)Show SMILES CC(C)N(C)C(=O)c1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C31H29F3N2O6S/c1-18(2)36(4)30(39)22-7-5-20(6-8-22)28-29(21-9-11-23(12-10-21)42-31(32,33)34)43-26(35-28)16-40-24-13-14-25(19(3)15-24)41-17-27(37)38/h5-15,18H,16-17H2,1-4H3,(H,37,38) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at human PPARdelta ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor gamma
(Homo sapiens (Human)) | BDBM50312420
(2-(4-((4-(4-(N-Isopropyl-N-methyl)benzamide)-5-(4-...)Show SMILES CC(C)N(C)C(=O)c1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C31H29F3N2O6S/c1-18(2)36(4)30(39)22-7-5-20(6-8-22)28-29(21-9-11-23(12-10-21)42-31(32,33)34)43-26(35-28)16-40-24-13-14-25(19(3)15-24)41-17-27(37)38/h5-15,18H,16-17H2,1-4H3,(H,37,38) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at human PPARgamma ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this Ligand-Target Pair | |
Peroxisome proliferator-activated receptor alpha
(Homo sapiens (Human)) | BDBM50312420
(2-(4-((4-(4-(N-Isopropyl-N-methyl)benzamide)-5-(4-...)Show SMILES CC(C)N(C)C(=O)c1ccc(cc1)-c1nc(COc2ccc(OCC(O)=O)c(C)c2)sc1-c1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C31H29F3N2O6S/c1-18(2)36(4)30(39)22-7-5-20(6-8-22)28-29(21-9-11-23(12-10-21)42-31(32,33)34)43-26(35-28)16-40-24-13-14-25(19(3)15-24)41-17-27(37)38/h5-15,18H,16-17H2,1-4H3,(H,37,38) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 690 | n/a | n/a | n/a | n/a |
The Genomics Institute of the Novartis Research Foundation
Curated by ChEMBL
| Assay Description Agonist activity at human PPARalpha ligand binding domain expressed in human 293T cells cotransfected with Gal4-DBD by luciferase transactivation ass... |
J Med Chem 53: 77-105 (2010)
Article DOI: 10.1021/jm9007399 BindingDB Entry DOI: 10.7270/Q28052RP |
More data for this Ligand-Target Pair | |