Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 540.0 BDBM50142810

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50142810 (4-{2-[1'-(2-Chloro-benzoyl)-[1,4']bipiperidinyl-4-...) Show SMILES CC(C)NC(=O)c1ccc(cc1)C1(OCCO1)C1CCN(CC1)C1CCN(CC1)C(=O)c1ccccc1Cl Show InChI InChI=1S/C30H38ClN3O4/c1-21(2)32-28(35)22-7-9-23(10-8-22)30(37-19-20-38-30)24-11-15-33(16-12-24)25-13-17-34(18-14-25)29(36)26-5-3-4-6-27(26)31/h3-10,21,24-25H,11-20H2,1-2H3,(H,32,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against cloned human muscarinic acetylcholine receptor M2.				Bioorg Med Chem Lett 14: 1791-4 (2004) Article DOI: 10.1016/j.bmcl.2004.01.033 BindingDB Entry DOI: 10.7270/Q22N51QH
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