Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 458.5 BDBM308835

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM308835 (4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)s...) Show SMILES CC(C)Oc1cccc(NC2CN(CC2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)c1 Show InChI InChI=1S/C23H27FN4O3S/c1-16(2)31-20-6-4-5-19(11-20)26-22-13-28(32(29,30)23-14-27(3)15-25-23)12-21(22)17-7-9-18(24)10-8-17/h4-11,14-16,21-22,26H,12-13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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