Marvin 2D Structure

The following exact ligands are found in BindingDB

Wt: 487.6 BDBM50111324

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 1 hit in this display   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M2 (Homo sapiens (Human))	BDBM50111324 (CHEMBL12542 | [4-(4-Isopropylsulfanyl-benzyl)-[1,4...) Show SMILES CC(C)Sc1ccc(CC2CCN(CC2)C2CCN(CC2)C(=O)c2nccc3ccccc23)cc1 Show InChI InChI=1S/C30H37N3OS/c1-22(2)35-27-9-7-23(8-10-27)21-24-12-17-32(18-13-24)26-14-19-33(20-15-26)30(34)29-28-6-4-3-5-25(28)11-16-31-29/h3-11,16,22,24,26H,12-15,17-21H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Binding affinity against muscarinic acetylcholine receptor M2 stably expressed in CHO-K1 cells using [3H]-QNB as radioligand.				Bioorg Med Chem Lett 12: 1087-91 (2002) BindingDB Entry DOI: 10.7270/Q2MS3S2P
					More data for this Ligand-Target Pair