Found 4 hits in this display Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human)) | BDBM585271
(US11530197, Compound 99)Show SMILES CC(C)n1cnc(c1-c1nc(c[nH]1)C(=O)Nc1ccc(cc1)N1CCN(CC1)C(N)=O)-c1ccc(F)cc1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
TNIK(h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM RLGRDKYKTLRQIRQ, 10 mM Magnesium Acetate and [gamma-33P-ATP](specific activity a... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2GF0ZCZ |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human)) | BDBM585271
(US11530197, Compound 99)Show SMILES CC(C)n1cnc(c1-c1nc(c[nH]1)C(=O)Nc1ccc(cc1)N1CCN(CC1)C(N)=O)-c1ccc(F)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The required volume of the 50× stock of test compound was added to the assay before a reaction mix containing the enzyme and substrate was added. The... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q270858G |
More data for this
Ligand-Target Pair | |
TRAF2 and NCK-interacting protein kinase
(Homo sapiens (Human)) | BDBM585271
(US11530197, Compound 99)Show SMILES CC(C)n1cnc(c1-c1nc(c[nH]1)C(=O)Nc1ccc(cc1)N1CCN(CC1)C(N)=O)-c1ccc(F)cc1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
The required volume of the 50× stock of test compound was added to the assay before a reaction mix containing the enzyme and substrate was added. The... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q270858G |
More data for this
Ligand-Target Pair | |
Mitogen-activated protein kinase kinase kinase kinase 4
(Homo sapiens (Human)) | BDBM585271
(US11530197, Compound 99)Show SMILES CC(C)n1cnc(c1-c1nc(c[nH]1)C(=O)Nc1ccc(cc1)N1CCN(CC1)C(N)=O)-c1ccc(F)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | >120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description
MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM RLGRDKYKTLRQIRQ, 10 mM Magnesium Acetate and [gamma-33P-ATP](specific activit... |
Citation and Details
BindingDB Entry DOI: 10.7270/Q2GF0ZCZ |
More data for this
Ligand-Target Pair | |